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D10R

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Rabbit fibroma virus (strain Kasza)
Length
260 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
30.46 kDa
Sequence
MNERLQYSHLMNYITKHNRKLSKTYTWNDDSQRVSATGFSNQRLRWSNKTSICLILSTLDNKFIACSRKHSFLYSEIVRCRSVFRKKRLFLTYTRFLKKKERPFLSSKLNVPLDDPGTEHNDIIFPGGLPKNEEDPIMCLSREIKEEINIDSKDIYIDSRFFVHLFIEDLLSNRVYETILFLGNTTLTSNEILNNFLANREIKSLVFLDALEKGLMCDVLRYVLAISQLKCFGSTGDKTELLYDKVTESEKKMAPRYGFD

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Rabbit fibroma virus (strain Kasza)
Length
260 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
30.46 kDa
Sequence
MNERLQYSHLMNYITKHNRKLSKTYTWNDDSQRVSATGFSNQRLRWSNKTSICLILSTLDNKFIACSRKHSFLYSEIVRCRSVFRKKRLFLTYTRFLKKKERPFLSSKLNVPLDDPGTEHNDIIFPGGLPKNEEDPIMCLSREIKEEINIDSKDIYIDSRFFVHLFIEDLLSNRVYETILFLGNTTLTSNEILNNFLANREIKSLVFLDALEKGLMCDVLRYVLAISQLKCFGSTGDKTELLYDKVTESEKKMAPRYGFD

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Vaccinia virus (strain Copenhagen)
Length
248 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
28.934 kDa
Sequence
MNFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMFRKKRLFLNYSNYLSKQERSILSSFFSLYPATADNDRIDAIYPGGIPKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Variola virus (isolate Human/India/Ind3/1967)
Length
248 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
28.911 kDa
Sequence
MNFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMSRKKRLFLNYSNYLNKQERSILSSFFSLDPATIDNDRIDAIYPGGILKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Vaccinia virus (strain Copenhagen)
Length
248 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
28.934 kDa
Sequence
MNFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMFRKKRLFLNYSNYLSKQERSILSSFFSLYPATADNDRIDAIYPGGIPKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD

Gene
D10R
Protein
mRNA-decapping protein D10
Organism
Variola virus (isolate Human/India/Ind3/1967)
Length
248 amino acids
Function
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
Similarity
Belongs to the Nudix hydrolase family.
Mass
28.911 kDa
Sequence
MNFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMSRKKRLFLNYSNYLNKQERSILSSFFSLDPATIDNDRIDAIYPGGILKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD