Protein
dTTP/UTP pyrophosphatase
Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Sequence
MVKIVLASGSPRRSELLKQIGLDFEIVLSDIDESNEENLKANELVQHLAYKKAYDVAKKVANRENGKERYLVVGADTVVVKDRIMGKPKDRDDAVRMLKHLSGSWHEVMTGIALIDTKDFRSVTSVEITKVKMKELTDDTILAYVDTKEPMDKAGAYGIQEKGAILVERIEGCYFNVVGLPLGRLSDLLKDFGVSVLKKI