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Cpin_4730

Gene
Cpin_4730
Protein
(-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
Organism
Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)
Length
321 amino acids
Function
Catalyzes the conversion of (2Z,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpene (1S,6S,7R)-(-)-gamma-cadinene via a 1,10-cyclization, which requires the abstraction of the pyrophosphate from FPP to yield a germacradienyl cation (PubMed:23307484, PubMed:27666571, PubMed:27829890). The only accepted substrate is (2Z,6E)-farnesyl diphosphate (FPP) (PubMed:27829890).
Similarity
Belongs to the terpene synthase family.
Mass
37.087 kDa
Sequence
MPTITLPRIIYPFPSLINQFVTAAHEQNRQWVADFGFITTPEAMARFDRSRFAWLAARAFPHAGFHELCTIANFNTWLFMLDDQCDEAQLGKKAVYLEHVTDGFMNILKHNTPVDTVLGRSFTDIWERMQALGDTAWQTRFIRSMEEYFTSCHWEAGNRAADIVPTVAEYVTMRPYTGALFADVEAIEIIEKVYLPAHILQHFIVQRLVLACNNIVCWANDIFSCAKEARQGDVHNLVLVLQHERNSTLQEAVNETARMHNEEVKLFTALEKLLPSFGAEMDRELERFMAVLRSWITANYDWSYHDTGRYQVKEVEVVINS