Protein
CMRF35-like molecule 3
Function
Acts as an activating receptor inducing cytokine production in mast cells. Can act as a positive regulator of TLR9 signaling in macrophages, leading to enhanced production of proinflammatory cytokines.
Similarity
Belongs to the CD300 family.
Sequence
MWQFPALLFLFLPGCCTAQDPVTGPEEVSGQEQGSLTVQCRYDSGWKDYKKYWCRGAYWKSCEILVETDASEQLVKENRVSIRDDQTDFIFTVTMEDLRMSDADIYWCGITKAGTDPMFKVNVNIDPEISTTIMTTTATVLPSTVLTSTVLTSTVLTPTTPTTESIGTENIGQVTQNSLFIWSLLSSISFLLMVFVVVPLLLSMLSAVLWVNRPQRHYGGGEIGLVETHRSDALDGEKHFPGDEK