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Cd200r1

Gene
CD200R1
Protein
Cell surface glycoprotein CD200 receptor 1
Organism
Bos taurus
Length
355 amino acids
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli (By similarity).
Similarity
Belongs to the CD200R family.
Mass
39.22 kDa
Sequence
MPCTWITSDLQLRLILTLFFVAECLSAGMEGTKTSNNSMQQLDNGNHSSVSTTSSTERKQSTVTLYAEVKTSLSVLVDTKAVLTCPPVLWPSVLVVTWEIVLRDKPPCFGAYRRDTNQTTRGNCTDKRITWASRPDENPALQVDPVAITHDGNYTCQIVTSDGNFHHEYHLQVLVPPEVTLIQTEKGTAVCKAAAGKPAAQISWTPEGDCDTEQGPYWGDGTVTVQSTCRWGSRHVLNVSCSVSHLAGNKSLSIQLSQGAEIPAHLKNLYITAPIFIILIVVGSIWLLKISGCRKCKLKKTEHTPVVQEDEMEPYASYTEKNNPLYDITNRVKTSQVLQSEVDGMNLHTIYVPRV

Gene
Cd200r1
Protein
Cell surface glycoprotein CD200 receptor 1
Organism
Rattus norvegicus
Length
327 amino acids
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli (By similarity).
Similarity
Belongs to the CD200R family.
Mass
35.534 kDa
Sequence
MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVNTTVFVQMGKKALLCCPSISLTKVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSNGTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGCICLLKISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCLTLSAMGI

Gene
Cd200r1
Protein
Cell surface glycoprotein CD200 receptor 1
Organism
Mus musculus
Length
326 amino acids
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli.
Similarity
Belongs to the CD200R family.
Mass
35.505 kDa
Sequence
MFCFWRTSALAVLLIWGVFVAGSSCTDKNQTTQNNSSSPLTQVNTTVSVQIGTKALLCCFSIPLTKAVLITWIIKLRGLPSCTIAYKVDTKTNETSCLGRNITWASTPDHSPELQISAVTLQHEGTYTCETVTPEGNFEKNYDLQVLVPPEVTYFPEKNRSAVCEAMAGKPAAQISWSPDGDCVTTSESHSNGTVTVRSTCHWEQNNVSDVSCIVSHLTGNQSLSIELSRGGNQSLRPYIPYIIPSIIILIIIGCICLLKISGFRKCKLPKLEATSAIEEDEMQPYASYTEKSNPLYDTVTKVEAFPVSQGEVNGTDCLTLSAIGI

Gene
CD200R1
Protein
Cell surface glycoprotein CD200 receptor 1
Organism
Homo sapiens
Length
325 amino acids
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Similarity
Belongs to the CD200R family.
Mass
36.62 kDa
Sequence
MLCPWRTANLGLLLILTIFLVAASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYRKETNETKETNCTDERITWVSRPDQNSDLQIRPVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAQISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL