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Capa

Gene
capA
Protein
Capsule biosynthesis protein CapA
Organism
Bacillus anthracis
Length
411 amino acids
Function
Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC.
Similarity
Belongs to the CapA family.
Mass
46.453 kDa
Sequence
MRRKLTFQEKLLIFIKKTKKKNPRYVAIVLPLIAVILIAATWVQRTEAVAPVKHRENEKLTMTMVGDIMMGRHVKEIVNRYGTDYVFRHVSPYLKNSDYVSGNFEHPVLLEDKKNYQKADKNIHLSAKEETVKAVKEAGFTVLNLANNHMTDYGAKGTKDTIKAFKEADLDYVGAGENFKDVKNIVYQNVNGVRVATLGFTDAFVAGAIATKEQPGSLSMNPDVLLKQISKAKDPKKGNADLVVVNTHWGEEYDNKPSPRQEALAKAMVDAGADIIVGHHPHVLQSFDVYKQGIIFYSLGNFVFDQGWTRTKDSALVQYHLRDNGTAILDVVPLNIQEGSPKPVTSALDKNRVYRQLTKDTSKGALWSKKDDKLEIKLNHKHVIEKMKKREKQEHQDKQEKENQVSVETTT

Gene
capA
Protein
PGA biosynthesis protein CapA
Organism
Bacillus subtilis (strain 168)
Length
380 amino acids
Function
Seems to be required for maximum PGA (gamma-polyglutamic acid) production.
Similarity
Belongs to the CapA family.
Mass
42.76 kDa
Sequence
MKKELSFHEKLLKLTKQQKKKTNKHVFIAIPIVFVLMFAFMWAGKAETPKVKTYSDDVLSASFVGDIMMGRYVEKVTEQKGADSIFQYVEPIFRASDYVAGNFENPVTYQKNYKQADKEIHLQTNKESVKVLKDMNFTVLNSANNHAMDYGVQGMKDTLGEFAKQNLDIVGAGYSLSDAKKKISYQKVNGVTIATLGFTDVSGKGFAAKKNTPGVLPADPEIFIPMISEAKKHADIVVVQSHWGQEYDNDPNDRQRQLARAMSDAGADIIVGHHPHVLEPIEVYNGTVIFYSLGNFVFDQGWTRTRDSALVQYHLKKNGTGRFEVTPIDIHEATPAPVKKDSLKQKTIIRELTKDSNFAWKVEDGKLTFDIDHSDKLKSK

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus
Length
221 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.496 kDa
Sequence
MESTIDLSELLGRVRKNMKLLIILPLLGLLISAIISFFFLDVKYQASTQILVNQKGNDSQIMAQEVQSNIQLVNTYSEIVKSPRILDKVSKELDDKYSRSEISSMLTVTNQAESQVLNIDVESKSGSNSEKIANKIAEVFSDEVPDIMNVDNVSVLSTADNTGKQVAPKPMVNLVVGLVIGLVIALLIIFIKEVFDKRIKTEEEVENELVIPVLGSIQKFD

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain MRSA252)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.368 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain MSSA476)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.34 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain MW2)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.34 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain COL)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.34 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.398 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSTALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capA
Protein
Capsular polysaccharide biosynthesis protein CapA
Organism
Staphylococcus aureus (strain N315)
Length
220 amino acids
Function
Required for the biosynthesis of type 1 capsular polysaccharide.
Similarity
Belongs to the CpsC/CapA family.
Mass
24.398 kDa
Sequence
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSTALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF

Gene
capa
Protein
Cardio acceleratory peptide 2b
Organism
Drosophila pseudoobscura pseudoobscura
Length
155 amino acids
Function
CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor. CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (By similarity).
Similarity
Belongs to the pyrokinin family.
Mass
16.958 kDa
Sequence
MKAIFSLYNIVSAILLLVLLAEFSTAELNHDKNRRGANMGLYAFPRVGRSDPSLANSLRDASDAAVFDGLYGDASQEDYNEADYQKRAGLVAFPRVGRSDAELRKFAHLLALQQVLDKRTGPSASSGLWFGPRLGKRSVDAKAFSDASKGQQEFN

Gene
capa
Protein
Cardio acceleratory peptide 2b
Organism
Drosophila pseudoobscura pseudoobscura
Length
155 amino acids
Function
CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor. CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (By similarity).
Similarity
Belongs to the pyrokinin family.
Mass
16.958 kDa
Sequence
MKAIFSLYNIVSAILLLVLLAEFSTAELNHDKNRRGANMGLYAFPRVGRSDPSLANSLRDASDAAVFDGLYGDASQEDYNEADYQKRAGLVAFPRVGRSDAELRKFAHLLALQQVLDKRTGPSASSGLWFGPRLGKRSVDAKAFSDASKGQQEFN

Gene
Capa
Protein
Cardio acceleratory peptide 2b
Organism
Drosophila melanogaster
Length
151 amino acids
Function
CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor (PubMed:12177421, PubMed:12459185). CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (PubMed:11959669). CAP-3 is a ligand for the PK1-R G-protein coupled receptor (PubMed:16054112).
Similarity
Belongs to the pyrokinin family.
Mass
16.507 kDa
Sequence
MKSMLVHIVLVIFIIAEFSTAETDHDKNRRGANMGLYAFPRVGRSDPSLANSLRDGLEAGVLDGIYGDASQEDYNEADFQKKASGLVAFPRVGRGDAELRKWAHLLALQQVLDKRTGPSASSGLWFGPRLGKRSVDAKSFADISKGQKELN

Gene
Capa
Protein
Cardio acceleratory peptide 2b
Organism
Drosophila melanogaster
Length
151 amino acids
Function
CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor (PubMed:12177421, PubMed:12459185). CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (PubMed:11959669). CAP-3 is a ligand for the PK1-R G-protein coupled receptor (PubMed:16054112).
Similarity
Belongs to the pyrokinin family.
Mass
16.507 kDa
Sequence
MKSMLVHIVLVIFIIAEFSTAETDHDKNRRGANMGLYAFPRVGRSDPSLANSLRDGLEAGVLDGIYGDASQEDYNEADFQKKASGLVAFPRVGRGDAELRKWAHLLALQQVLDKRTGPSASSGLWFGPRLGKRSVDAKSFADISKGQKELN

Gene
capA
Protein
Cold shock protein CapA
Organism
Pseudomonas fragi
Length
64 amino acids
Function
Affects cell viability at low temperatures.
Mass
7.016 kDa
Fragment
single
Sequence
MSQRQSGTVKWFNDEKGFGFITPQGGGDDLFVHFKAIESDGFKSLKEGQTVSFVAEKGQKGMQA