Function
Highly active in 7-ethoxycoumarin O-deethylation, and benzphetamine N-demethylation; moderately active in testosterone 7-alpha-hydroxylation, ethylmorphine N-demethylation, p-nitroanisole O-demethylation; and only slightly active in benzopyrene 3-hydroxylation, 7-ethoxyresorufin O-deethylation, testosterone 2-alpha-hydroxylation and testosterone 17-oxidation. Competent in the metabolic activation of aflatoxin B1.
Sequence
MLVSGMLLVVVLTCLSVMIIMSVWRQRRLLRKMPPGPTPLPFIGNFLELDTEKFYDCLSKMRERYGPVFTIHLGPRPAVMLWGYDAVKEALIDQAEELSDRGEQAFFDWFFKGYGVVFSSGERAKQLRRFSIATLRDFGFGKRGIEERTIEETSFLIQALRDTNGATIDPTFYMSRTVSNVISSIVFGNRFEYDDKEFLSLLGMIMRSFQFMSTSTGQLFEMFYSVMKHLPGCQHQAYKEMQGLEDFIARKVEENQRTLDPNSPRDFIDSFLIRMQEEKKNPRTQFHMRNLLMTTLNLFFAGTETVSTTTRYGFLLLMKYPHIAAKMHEEIDQVIGRNRQPKYEDHLKMPYTEAVIYEIQRFVDVVPLGLPRSTTKDIKFRDFLIPKGTDVFPVLSSVLKDPKFFSNPNDFNPQHFSDDKGQFKKSNAFMPFSVGKRYCFGESLAKMELFIFFTTIMQNFCFKSPQAPQDIDVTPQYFSFAAIPPKFTMSFLPR