CX3CR1

Gene

CX3CR1

Protein

CX3C chemokine receptor 1

Organism

Bos taurus

Length

358 amino acids

Function

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

40.849 kDa

Sequence

MHTTLPESTSENFEYYDLAEACDMGDIVALGTVFVVILYSLVFAFGLVGNLLVVFALINSQRSKSITDIYLLNLALSDLLFVATLPFWTHYVINEQGLHHATCKLITAFFFIGFFGGIFFITVISVDRFLAIVLAANSMSNRTVQHGVTTSLGVWAAAILVATPQFMFTREKENECFGDYPEILQEIWPVILNTEINFLGFLLPLLIMSYCYFRIMQTLFSCKNHKKAKAIRLIFLVVVVFFLFWTPYNVMIFLQTLNLYDFFPKCDVKRDLKLAISVTETIAFSHCCLNPLIYAFAGEKFRRYLYRLYRKCLAVLCCHPDHLSFSSSLSESQRSRRESVLSSNFTHYTSDGDASILL

Protein

CX3C chemokine receptor 1: CX3CR1

Gene

CX3CR1

Protein

CX3C chemokine receptor 1

Organism

Oryctolagus cuniculus

Length

356 amino acids

Function

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

40.234 kDa

Sequence

MTTLYSDWATESFEYDESSEACFIGDIVAFGTIFLSIFYSLVFAFGLVGNLLVVCALTSSRKPKSITDIYLLNLALSDLLFVATLPFWTHYVISEQGFHNAVCKLTTALFFIGFFGGIFFITVISIDRYMAIVLAANSINNRTVQHGVTTSLGVWAAAILVAAPQFMFTKQKGNECLGDYPEVLQDIWPVLRNTEANFLGFLLPVLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYGFFPNCDMKRDLRLALSVTETVAFSHCCLNPLIYAFAGQKFRRYLRHLSRKCQAVLCGRPVHVSFSPSESQRSRQESIVSSNFTHYTSDGDASLLL

Protein

CX3C chemokine receptor 1: CX3CR1

Gene

CX3CR1

Protein

CX3C chemokine receptor 1

Organism

Homo sapiens

Length

355 amino acids

Function

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed:14607932).

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

40.396 kDa

Sequence

MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL

Protein

CX3C chemokine receptor 1: CX3CR1

Gene

Cx3cr1

Protein

CX3C chemokine receptor 1

Organism

Mus musculus

Length

354 amino acids

Function

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

40.266 kDa

Sequence

MSTSFPELDLENFEYDDSAEACYLGDIVAFGTIFLSVFYALVFTFGLVGNLLVVLALTNSRKPKSITDIYLLNLALSDLLFVATLPFWTHYLISHEGLHNAMCKLTTAFFFIGFFGGIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVASPQFMFTKRKDNECLGDYPEVLQEMWPVLRNSEVNILGFALPLLIMSFCYFRIIQTLFSCKNRKKARAVRLILLVVFAFFLFWTPYNIMIFLETLKFYNFFPSCDMKRDLRLALSVTETVAFSHCCLNPFIYAFAGEKFRRYLGHLYRKCLAVLCGHPVHTGFSPESQRSRQDSILSSFTHYTSEGDGSLLL

Protein

CX3C chemokine receptor 1: Cx3cr1

Gene

Cx3cr1

Protein

CX3C chemokine receptor 1

Organism

Rattus norvegicus

Length

354 amino acids

Function

Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

40.327 kDa

Sequence

MPTSFPELDLENFEYDDSAEACYLGDIVAFGTIFLSIFYSLVFTFGLVGNLLVVLALTNSRKSKSITDIYLLNLALSDLLFVATLPFWTHYLISHEGLHNAMCKLTTAFFFIGFFGGIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVASPQFMFTKRKDNECLGDYPEVLQEIWPVLRNSEVNILGFVLPLLIMSFCYFRIVRTLFSCKNRKKARAIRLILLVVVVFFLFWTPYNIVIFLETLKFYNFFPSCGMKRDLRWALSVTETVAFSHCCLNPFIYAFAGEKFRRYLRHLYNKCLAVLCGRPVHAGFSTESQRSRQDSILSSLTHYTSEGEGSLLL

Protein

CX3C chemokine receptor 1: Cx3cr1