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CUSTOS

Gene
Custos
Protein
Protein CUSTOS
Organism
Rattus norvegicus
Length
277 amino acids
Function
Plays a role in the regulation of Wnt signaling pathway during early development.
Similarity
Belongs to the CUSTOS family.
Mass
30.056 kDa
Sequence
MVAPSGAMSDSESSSSDSSDAEELARCREAATPAWGLEQRPREAERPAAGTADTQAPAPQPSRRREVNQHDEDGNELQTTPEFRAYVAKKLGALLDSSIAIAEVWKKTQQARLQQEAKEQQEAKEQQAAKEEQAAKKEEDGFRLFFTSVPGGHEKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKVEKEAEKKKLKKKAKKKADADLAAATGLEQVKEAGSVNGDPVLSGTKKKKKKKAKKAREASLCPPAECAAAEPKN
Protein
Protein CUSTOS: Custos

Gene
CUSTOS
Protein
Protein CUSTOS
Organism
Homo sapiens
Length
262 amino acids
Function
Plays a role in the regulation of Wnt signaling pathway during early development.
Similarity
Belongs to the CUSTOS family.
Mass
28.171 kDa
Sequence
MAAPSGTVSDSESSNSSSDAEELERCREAAMPAWGLEQRPHVAGKPRAGAANSQLSTSQPSLRHKVNEHEQDGNELQTTPEFRAHVAKKLGALLDSFITISEAAKEPAKAKVQKVALEDDGFRLFFTSVPGGREKEESPQPRRKRQPSSSSEDSDEEWRRCREAAVSASDILQESAIHSPGTVEKEAKKKRKLKKKAKKVASVDSAVAATTPTSMATVQKQKSGELNGDQVSLGTKKKKKAKKASETSPFPPAKSATAIPAN
Protein
Protein CUSTOS: CUSTOS

Gene
CUSTOS
Protein
Protein CUSTOS
Organism
Bos taurus
Length
257 amino acids
Function
Plays a role in the regulation of Wnt signaling pathway during early development.
Similarity
Belongs to the CUSTOS family.
Mass
27.813 kDa
Sequence
MSDLESSSSSSSDEEELERCREAALPAWGLEQRPRGPEKPGVDATNAKLPANQPSLMHKVDEHEQDGNELQTTPEFRAHVAKKLGALLDSSITISEIVKEPRKSEVQQGALEDDGFRLFFTSIPGGPEKEAAPQPCRKRLPSSSSSDDGDEELRRCREAAVSASDILQESAIHGHVSVEKKKKRKLKKKAKKEDSADVAATATSKAEVGRQEKESAQLNGDQAPPGTKKKKRKKKTKKASEASLSPPTKSAAAVPSN
Protein
Protein CUSTOS: CUSTOS

Gene
Custos
Protein
Protein CUSTOS
Organism
Mus musculus
Length
256 amino acids
Function
Plays a role in the regulation of Wnt signaling pathway during early development.
Similarity
Belongs to the CUSTOS family.
Mass
27.631 kDa
Sequence
MVAPSGAMSDSENSSSSSSDAEELARCREAATPAWGLEQRPGAAERPEAGAADKQAPTPQPSRRHEVNQHEEDGNDLRTTPEFRAHVAKKLGALLDSSIAIAEVWKKSQKAKMQQVAKEEDGFRLFFTSIPGGHKKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKAEEKKKLKKKAKKKVDNADLAAAPGLEQVKEAGVVNGDPVSLGIQKKRKKKAKKSREAPLCPPAECAAAKPEN
Protein
Protein CUSTOS: Custos

Gene
custos
Protein
Protein CUSTOS
Organism
Xenopus laevis
Length
237 amino acids
Function
Essential for Spemann-Mangold organizer formation and subsequent anterior head development in the embryo. Inhibits canonical Wnt signaling pathway by antagonizing nuclear import of beta-catenin (ctnnb1) during embryogenesis.
Similarity
Belongs to the CUSTOS family.
Mass
26.515 kDa
Sequence
MAAPRRGTQKSDSDSSDEDLDRFREAAWVPPGAHQKVSDEQNEKIALPSLRVRPDCHEHDGNELQTTPEFRSHVAKKLAAILDSSIREVSQNEAVHISKAGNGDSEDEGFRLFRTSLPGEAGIVTSTIPRRKLASSSSEDSEEEQQRCREAAVSACDILRHSTLQQEPQSTPSNVCDNQPPKKKRKKKKKDRGDTSQINSVEETMHIEPGKNELQAKRKKKKKQKLEMAHCDELGNE
Protein
Protein CUSTOS: custos

Gene
custos
Protein
Protein CUSTOS
Organism
Danio rerio
Length
236 amino acids
Function
Essential for Spemann-Mangold organizer formation and subsequent anterior head development in the embryo. Inhibits canonical Wnt signaling pathway by antagonizing nuclear import of beta-catenin (ctnnb1) during embryogenesis.
Similarity
Belongs to the CUSTOS family.
Mass
26.81 kDa
Sequence
MSESSSEDENTARLKEAVWSFKPEDVKINGKENNGRQSHRADVSKHEHDGNELGTTPEFRSHVAKKLGTYLDGCISEVCSDTVEPAQSENREDEEGFRLFSSSTPGKWMEQSPPPPPKRRPVPSSSDSDSEMEMRFREAAVSLSDILGPVAQNLSEKTEEKSTKEETEDTVTKMKKKKKRKTSSEESQDKVNHQTEKQSNVEGNQEQTTAGERLKKKKKKKKKKRKKLEKDIKKDE
Protein
Protein CUSTOS: custos