Protein
dTTP/UTP pyrophosphatase
Organism
Clostridium tetani (strain Massachusetts / E88)
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Sequence
MNFILASSSERRKELLKRIVENFEVIPSDYDEKEVAFNGNCSEYVMELSKGKALNVASKLKRDSGIIIASDTIVYFNGEVLGKPSSKEHAYEMLKSLSGEVHEVYSGIVIYDLSSKKIKADYSCSKVKFSNLDDKMIREYIKTGEPMDKAGSYGIQGYGGIFVEKIHGCYYNIVGLPINKLYFLLKEMGVNL