CRK

CDPK-related protein kinase

602 amino acids

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

67.184 kDa

MGICVSKPSPEPDLHNHHTSIPVNDTSLPPQDNSIPPKDIAIPAQDNNKPPGKKSPFLPFYSPSPAHFLFSKKSPAVGSPAAGSSNSTPKRLFPFPPPSPAKHIKAAWARRHGSVKPNEAAIPENNEVDGGAGLDKSFGFSKKFGSKFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRALTGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFCHLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLSDYVKPDERLNDIVGSAYYVAPEVLHRSYSTEADVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSSEAKDFVKRLLNKDPRKRMTAAQALCHSWIKNSNDIKFPLDILVFKLMKVYMRSSPLRKAALRALSKTLTVDELFYLKEQFVLLEPTKNGTISLENIKQALMRNSTDAMKDSRVLDLLVSLNALQYRRMDFEEFCAAALSVHQLEALDRWEQHARCAYDLFEKDGNRAIMIEELASELGLGPSIPVHAVLHDWIRHTDGKLSFLGYVKLLHGVSTRAIAKAQ

CRK

Cell division control protein 2 homolog

474 amino acids

Probably involved in the control of the cell cycle.

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

53.473 kDa

MSTLGRYRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKELRHNNVVELFEVLFDPPKITMIFELCDCDLKRYMESRPQRLLDANTEMRPILKQIFLGLEYLHGRCVVHRDMKPQNIFVNVRGPDFAAMTALPSSPQQSMRVPHAGGTNGEAGRASANGNEHAPRPTAAEGSVSPWEEAANTKDAPNQLIIKIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMSSALYSYPVDIWSMGAIFFEMATSKVLFSGRNEDEQLLRMFWLLGSPTKETWPSMMTYTGTMERLERSSRAAAERQDLTVNGDVYVQQQQLQAQQQQPQQGSSPSHSSSRAPDLLTQLAHKRFYHSESAMQQRRESASSAANSYRLPVELWFDRPLFKEYMAATRCDVSVSPEGIDLLRRCLMYEPNQRITAAEAVHHPYLERVPVPTAGSLDVLISSLMQTMETIHLL

CRK

Adapter molecule crk

305 amino acids

May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).

Belongs to the CRK family.

33.806 kDa

MAGQFDSEDRGSWYWGRLSRGDAVSLLQGQRHGTFLVRDSGSIPGDFVLSVSESSRVSHYIVNSLGPAGGRRAGGEGPGAPGLNPTRFRIGDQEFDSLPSLLEFYKIHYLDTTTLIEPVSRSRQNSGVILRQEEVEYVRALFDFNGNDDEDLPFKKGDILKIRDKPEEQWWNAEDMDGKRGMIPVPYVEKCRPSSASVSTLTGGNQDSSHPQPLGGPEPGPYAQPSINTPLPNLQNGPFYARVIQKRVPNAYDKTALALEVGELVKVTKINMSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS

Crk

Adapter molecule crk

304 amino acids

Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Belongs to the CRK family.

33.845 kDa

MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPEEDFS

CRK

Adapter molecule crk

304 amino acids

Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Belongs to the CRK family.

33.831 kDa

MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS

Crk

Adapter molecule crk

304 amino acids

Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Belongs to the CRK family.

33.815 kDa

MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVARSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS

crk

Adapter molecule crk

296 amino acids

Required for apoptosis in Xenopus egg extracts. May mediate attachment-induced mapk8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the efna5-epha3 signaling (By similarity).

Belongs to the CRK family.

33.409 kDa

MAGNFDSEDRASWYWGKQNRQEAVNLLQGQRHGVFLVRDSTTIPGDYVLSVSENSKVSHYIINSVTNNRQSSTAGMVQSRFRIGDQEFDSLPTLLEFYKIHYLDTTTLIEPVSKSKQSGVIQRQEEVEYLRALFDFIGNDDEDLPFKKGDILRIREKPEEQWWNAEDSDGRRGMIPVPYVEKYRPPSSPGSALIGGNQENSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIFARVIQKRVPNAYDKTALALEVGDLVKVTKINVSGQWEGECNGKYGHFPFTHVRLLEQNPEEDFS

Crk

Adapter molecule Crk

271 amino acids

Adapter protein which interacts with C-terminal portion of mbc, homolog of human DOCK180. May play a role in cellular processes throughout development.

Belongs to the CRK family.

31.205 kDa

MDTFDVSDRNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQIVYRIGDQSFDNLPKLLTFYTLHYLDTTPLKRPACRRVEKVIGKFDFVGSDQDDLPFQRGEVLTIVRKDEDQWWTARNSSGKIGQIPVPYIQQYDDYMDEDAIDKNEPSISGSSNVFESTLKRTDLNRKLPAYARVKQSRVPNAYDKTALKLEIGDIIKVTKTNINGQWEGELNGKNGHFPFTHVEFVDDCDLSKNSTEIC