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CPXV209

Gene
CPXV209
Protein
Interleukin-1-binding protein
Organism
Cowpox virus (strain Brighton Red)
Length
326 amino acids
Function
Binds interleukin-1 and possibly interleukin-6. Could prevent these cytokines reaching their natural receptors. In consequence the inflammatory response would be diminished and virus replication enhanced.
Similarity
Belongs to the interleukin-1 receptor family.
Mass
36.79 kDa
Sequence
MSIPPVIFLPIFFYSSFVQAFNAPECIDKGQYFASFMELENEPVILPCPQINTISSGYNILDILWEKRGADNDRIIPIDNGSNMLILNPTQSDSGIYICITKNETYCDMMSLNLTIVSVSESNIDLISYTQIVNERTTGEMVCPNINAFIASNVNADIIWSGHRRLRNKRLRQRTPGIITIEDVRKNDAGYYTCVLKYTYGDKTYDVTRIVKLEVRDRMIPPTMQLPDGVVTSIGSNLTIACRVSLRPPTTDADVFWISNGMYYEEDDEDGDGRISVANKIYTTDKRRVITSRLKINPVKEEDATTFTCMAFTIPSISKTVTISIT