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CPI17

Gene
CPI17
Protein
Protein phosphatase 1 regulatory subunit 14A
Organism
Sus scrofa
Length
147 amino acids
Function
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Similarity
Belongs to the PP1 inhibitor family.
Mass
16.672 kDa
Sequence
MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELESEEERSRKIQGLLKSCTNPTENFVQELLVKLRGLHKQPGLRQPSPSGDGSLSPRQDRARTAPP