CLEC10A

C-type lectin domain family 10 member A

316 amino acids

Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.

35.446 kDa

MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGFQNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVSELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGLGQTSQESH

Clec10a

C-type lectin domain family 10 member A

306 amino acids

Recognizes terminal galactose and N-acetylgalactosamine units.

34.242 kDa

MTMAYENFQNLGSEEKNQEAGKAPPQSFLCNILSWTHLLLFSLGLSLLLLVVISVIGSQNSQLRRDLETLRTTLDNTTSNTKAELQALASRGDSLQTGINSLKVEVDDHGQELQAGRGLSQKVASLESTVEKKEQTLRTDLSEITDRVQQLGKDLKTLTCQLASLKNNGSAVACCPLHWMEHEGSCYWFSQSGKPWPEADKYCQLENSNLVVVNSLAEQNFLQTHMGSVVTWIGLTDQNGPWRWVDGTDYEKGFTHWAPKQPDNWYGHGLGGGEDCAHFTSDGRWNDDVCQRPYRWVCEMKLAKDS

Clec10a

C-type lectin domain family 10 member A

304 amino acids

Recognizes terminal galactose and N-acetylgalactosamine units. May participate in the interaction between tumoricidal macrophages and tumor cells. Plays a role in the recruitment of inflammatory monocytes to adipose tissue in diet-induced obesity.

34.596 kDa

MIYENLQNSRIEEKTQEPGKAPSQSFLWRILSWTHLLLFSLGLSLLLLVVVSVIGSQNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES