Protein
tRNA-splicing ligase RtcB homolog
Organism
Chlamydomonas reinhardtii
Function
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
Similarity
Belongs to the RtcB family.
Sequence
MHVPGTFYVNDALKGLLFEELQQAVVRGDHGGFLPAVKQLANVAALPGIVKRSIALPDVHSGYGFAIGNVAAFDMDNPEAVVSPGGVGFDINCGVRLLRTNLTEAEVGPVREQLAQALFDHIPVGVGSQGIIPTTAKDMESALELGMDWSLREGYAWAEDKEHCEEYGRMLNADPRYVSSRAKKRGLPQMGTLGAGNHYAEVQVVDEVYDAVAARRMGIDTPGQVVVMIHSGSRGLGHQVATDALVAMERAMARDGIITNDRQLACARINSEEGQAYLKAMSCAANYAWVNRSSMTFLARQAFAKIFKSTPDDLDMHVVYDVSHNIAKVEQHCVDGQHRRLLVHRKGSTRAFPPHHPLIPADYQLIGQPVLVGGTMGTSSYVLTGTEQGFTETFGSTCHGAGRARSRNNSRNKLDYQDVLDNLKAKGIAIRVASPKLVMEEAPESYKDVSEVVDTCHQAGISKKAVKLRPIAVIKG