CEP78

Gene

Cep78

Protein

Centrosomal protein of 78 kDa

Organism

Mus musculus

Length

790 amino acids

Function

May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.

Similarity

Belongs to the CEP78 family.

Mass

86.89 kDa

Sequence

MIDSVKLRRDCAADFFSHYEYLCALQDSVPLPAVRACLRDGVLDFNADRLRAVDWAPLLSTLRVNRDLPLVAIKSSFQPWLGETVLRSGGADTHRICRNRVPAVRSKDISFQLCKALRGCLSVSGVLRNLELNGLILRERDLTSLTKGLSKSTSLVHLSLANCPIGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGACHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSEGAKALLEALETNRTLVVLDIRKNPLIDHSMMKAVIKKVLQNGRSADSEYQWVTSPSSKEPSKTAKQRKKTIVLGSSRKGKATIRIGLATKKPSSNGRKQGLGKDCYAPNPLPPGASGFLPWRTAERAKRSRSSSLIKTRDLSNHLKKSDFPVTVTVESPSSSETDETEDSSESVQEAPQKTSIKEETLQEKLEECLRQLKEERVIRLKADKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFHLLGRPQMNSTVNTPIQEQKALEDETLHPKQTATGQMQDIRFQKITSDALIPLPLNTVQDPASAQEAVGASRDHLGVVGLEQQEGSAAGFIAKTGSPLAGGIPGGRSQREEEVLSKHSRSSSEKGSTASEPSRRPSAERHPRKDLLSDADPPGNSESKGPGDRRSLLNEPIKSESLKKCISIKKENRIVTVSSKTIKSKPNLLEHSESDTLGSDFELQERVHSSAHLT

Protein

Centrosomal protein of 78 kDa: Cep78

Gene

cep78

Protein

Centrosomal protein of 78 kDa

Organism

Xenopus tropicalis

Length

727 amino acids

Function

May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.

Similarity

Belongs to the CEP78 family.

Mass

80.582 kDa

Sequence

MIDSVRIRHQGSMDFLSHYEYLCALQDSVPIPAVKANIRHGSLSFNADRIKLSDWLPILNSLKINKSLLNVSIKSCHQPGLGEFGAEKYGIYFKRRIPPIRSKDMTFQVCKAITSCLSVSGSLKELELHGLPLRERDLRILAKGLAASSSVESLSLAYCSCGDEGLEIICQSVKNSPTIKTVNFTGCNLTWRGAEHIASIIKHQATRRHSEAWAESLRYRRPDLDCMAGLRRVTLNSNTLVGDRGAIALAEVIGEDLWLKALDLRQCGISNEGAQAFLNAFQTNTTLIILDIRRNPLIDRSLLKTIIERVLMNAHDTNSEYKWYTSPSSKDNGKVRQKWRSINNWNGRKGKNIVRVGFSTKKPMVIGRKYSSKELYCPDPRPPGAEGFLPWRTAERAKRHRDVSGEWASPGKADTAVKVIMDSETSSESEKSDNILSILDQEYAVPGSGEKKSVKNYKCLQLEFENTRLRQINHTLSESLHSRTATSVILEDEGVLDSIEKSFSKFHAFLDLLKDAGLGQLANLAGIDQSDFALPGDPQMSSTIDKIAQQAPMPHQDQQETFFIHQAQSRDKKGEHTGPSESNALTADTLPSSREADKYCTTSQKSKEGFDPDLKAREANVNSGRLPALENAQTYLYDKKGSRNECSASDSSRSQRSSLGQKSKASASEKERKPSSKRSHSSGTNKASQESIAARDEKAAARSNASISESEIQEKMNSSESMHSGSH

Protein

Centrosomal protein of 78 kDa: cep78

Gene

CEP78

Protein

Centrosomal protein of 78 kDa

Organism

Homo sapiens

Length

689 amino acids

Function

May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles (PubMed:27246242). May play a role in cilium biogenesis (PubMed:27588451).

Similarity

Belongs to the CEP78 family.

Mass

76.396 kDa

Sequence

MIDSVKLRRDSAADFFSHYEYLCALQNSVPLPAVRACLREGVLDFNADRLRGVDWAPLLSTLKINKDLPLVSIKSFFQPWLGDTGSDMNKFCRSRVPAIRYKDVTFQLCKALKGCLSISSVLKNLELNGLILRERDLTILAKGLNKSASLVHLSLANCPIGDGGLEIICQGIKSSITLKTVNFTGCNLTWQGADHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDIRKNPLIDHSMMKAVIKKVLQNGRSAKSEYQWITSPSVKEPSKTAKQKRRTIILGSGHKGKATIRIGLATKKPVSSGRKHSLGKEYYAPAPLPPGVSGFLPWRTAERAKRHRGFPLIKTRDICNQLQQPGFPVTVTVESPSSSEVEEVDDSSESVHEVPEKTSIEQEALQEKLEECLKQLKEERVIRLKVDKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFQLLGHPQMTSTVSNPPKEEKKALEDEKPEPKQNALGQMQNIQFQKITGDARIPLPLDSFPVPVSTPEGLGTSSNNLGVPATEQRQESFEGFIARMCSPSPDATSGTGSQRKEEELSRNSRSSSEKKTKTESH

Protein

Centrosomal protein of 78 kDa: CEP78