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CENPQ

Gene
CENPQ
Protein
Centromere protein Q
Organism
Gallus gallus
Length
283 amino acids
Function
Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May play an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Similarity
Belongs to the CENP-Q/OKP1 family.
Mass
32.203 kDa
Sequence
MKRHRASSGKRGETADGGRVKRPTKSHNQQGPTSQKRGTVGKGDKRAQKRKLVTQAVRREDEEHEDSSSAGEKGHSKKVKLSSAKVESWQPLSESSRKFLESVMDSGILSILCQQSKGKEDVQKHLNLLKERVLRVFKTLKVPLGKLSNLNNVLSFQVAQKQMLEMNETALVQLQEEINEAEKSAERTEETILRLQHDIQVLKSQLEEEEKKARKLCREGDTKELHLPELPKCSLQAPTLQEEILMVKNQKGLLEDMNTIQQSADMRNMLTFIEKIYEKVDLV

Gene
Cenpq
Protein
Centromere protein Q
Organism
Rattus norvegicus
Length
270 amino acids
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Similarity
Belongs to the CENP-Q/OKP1 family.
Mass
31.002 kDa
Sequence
MSGKANTSKKKSQRVKRNVKQRADKEDEELDSPENKVGNRAKRNRSHAGHLSSKEQTKCVHLKRVKISSNKRTAWQPLPKNTEEYLQSMMDSAILGILNKNIKRKEQIQYHLDQLKKRFLQQCATLKVPPGKLNYLRDMSKLLKVEREQERANEESLASLQEEIDKIVETTESMTENIESLKTKIEILTNEVEKEEEEMKEVFHIDSNKVLALPELSQKSLKAPILQKEILTLIPNQNALLKDLDVLQNSAPGKNMAAFIQEAYMKLNGS

Gene
CENPQ
Protein
Centromere protein Q
Organism
Homo sapiens
Length
268 amino acids
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (PubMed:16622420). Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores (PubMed:25395579).
Similarity
Belongs to the CENP-Q/OKP1 family.
Mass
30.595 kDa
Sequence
MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS

Gene
CENPQ
Protein
Centromere protein Q
Organism
Macaca fascicularis
Length
268 amino acids
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Similarity
Belongs to the CENP-Q/OKP1 family.
Mass
30.98 kDa
Sequence
MSGKANASKKNFEQLKRNPKRKKDNEEVVLSEKKVRNTVKRNKNHLKDLFSEGQTKHTNLKQIKIAPNKRKTWQPLSKSTRDYLQTMMESVLRTILSDRIKDKEEIQYHLNFLKNRLLQLCETLKVPPKKMEDLTNVSRLLNMERARGKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQIHQINTSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSHMKSMSTFIEEAYKKLNAS

Gene
Cenpq
Protein
Centromere protein Q
Organism
Mus musculus
Length
267 amino acids
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Similarity
Belongs to the CENP-Q/OKP1 family.
Mass
30.501 kDa
Sequence
MSGKARASRKKPQQVKRSLKQRANKEADLPENEVGNTAKRNRSHAKHLSSKVTGQATYVHLKRVKISSSKRTTWQPLPKDTEEYLQSMMESVILGILFNIKRKEEIQCHLNQLKKRLLQQCATLKVPPRKLNYLKDVSKMLKMEKAQERANEESLASLQEEIDKIVETTESMTESIQSLKNKIQILTSEVEEEEQEVKQVFHIDSNKVLALPELSQKSLKAPILQEEILALIPNQNALLKDLDVLHDSAPVKNVSAFIEEAYKKLDS