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CDX2

Gene
CDX2
Protein
Homeobox protein CDX-2
Organism
Homo sapiens
Length
313 amino acids
Function
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Similarity
Belongs to the Caudal homeobox family.
Mass
33.52 kDa
Sequence
MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGGVLNPTVTQ
Protein
Homeobox protein CDX-2: CDX2

Gene
CDX2
Protein
Homeobox protein CDX-2
Organism
Mesocricetus auratus
Length
313 amino acids
Function
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (By similarity).
Similarity
Belongs to the Caudal homeobox family.
Mass
33.56 kDa
Sequence
MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWSTAYGAPLREDWNGYPPGGAAAANAVAHGLNGGSPAAAMGYSSPADYHAHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATGAAEQLSPSGQRRNLCEWMRKPAQPSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQQQQQLASPPPQPSQPQPGSLRSVPEPLSPVSSLQGSVPGSVPGVLGPAGGVLNPTVTQ
Protein
Homeobox protein CDX-2: CDX2

Gene
Cdx2
Protein
Homeobox protein CDX-2
Organism
Mus musculus
Length
311 amino acids
Function
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
33.476 kDa
Sequence
MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAATANLDSAQSPGPSWPTAYGAPLREDWNGYAPGGAAAANAVAHGLNGGSPAAAMGYSSPAEYHAHHHPHHHPHHPAASPSCASGLLQTLNLGPPGPAATAAAEQLSPSGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQVKIWFQNRRAKERKIKKKQQQQQQQQQQQPPQPPPQPSQPQPGALRSVPEPLSPVTSLQGSVPGSVPGVLGPAGGVLNSTVTQ
Protein
Homeobox protein CDX-2: Cdx2