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CDX1

Gene
Cdx1
Protein
Homeobox protein CDX-1
Organism
Mus musculus
Length
268 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
28.436 kDa
Sequence
MYVGYVLDKDSPVYPGPARPSSLGLGPPTYAPPGPAPAPPQYPDFAGYTHVEPAPAPPPTWAAPFPAPKDDWAAAYGPGPTASAASPAPLAFGPPPDFSPVPAPPGPGPGILAQSLGAPGAPSSPGAPRRTPYEWMRRSVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPLPPTQLPLPLDGTPTPSGPPLGSLCPTNAGLLGTPSPVPVKEEFLP
Protein
Homeobox protein CDX-1: Cdx1

Gene
CDX1
Protein
Homeobox protein CDX-1
Organism
Homo sapiens
Length
265 amino acids
Function
Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Similarity
Belongs to the Caudal homeobox family.
Mass
28.138 kDa
Sequence
MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPPMAHDITATPAGPSLGGLCPSNTSLLATSSPMPVKEEFLP
Protein
Homeobox protein CDX-1: CDX1

Gene
CDX1
Protein
Homeobox protein CDX-1
Organism
Pongo pygmaeus
Length
265 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
28.318 kDa
Sequence
MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFPSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRRTPYEWMRRSVAAGGGGVSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPPTAHDITATPARPSLGGLCPSNTSLLATSSPMPVKEEFLP
Protein
Homeobox protein CDX-1: CDX1

Gene
cdx1
Protein
Homeobox protein CDX-1
Organism
Xenopus laevis
Length
263 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1. Binds to the PRKD1 promoter. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
29.201 kDa
Sequence
MYVGYLLDKDNNMYPNPVRHPGLNLNPQNYVPAPPQYSDFPSYHHVPGINSDPHHGQPGGTWSSYTPSREDWHPYGPGPGASSANPTQIAFSPSDYNPVQPPGSGLLPPSINSSVPPLSPSAQRADPYEWMRRTGVPTTTTTTNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAALGLTERQVKIWFQNRRAKERKVNKKKMQQQSQQASTTTPTPPSVGTTAGMGGLCSSSSSNSNLVSPSSMPIKEEYLS
Protein
Homeobox protein CDX-1: cdx1

Gene
cdx1
Protein
Homeobox protein CDX-1
Organism
Xenopus tropicalis
Length
262 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1. Binds to the PRKD1 promoter. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
29.201 kDa
Sequence
MYVGYLLDKDNNMYPNPVRHPGLNLNPQNYVPAPPQYSDFPSYHHVPGINSDPHHGQPGGTWSSYTPSREDWHPYGPGPGASSANPAQISFSPSDYNPVQPPGPGLLPPSLNSSVSPLSPSAQRRNLYEWMRRTGVPTSTNSNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVKIWFQNRRAKERKVNKKKMQQQSQQASTTTPTPPSVGTTAGMGGLCSSSSSNSNLVSPSSMPIKEEYLS
Protein
Homeobox protein CDX-1: cdx1

Gene
CDX1
Protein
Homeobox protein CDX-1
Organism
Gallus gallus
Length
260 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1. Binds to the PRKD1 promoter. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
28.844 kDa
Sequence
MYVGYLLDKDTNMYPSPVRHPSLNLNPQNYVPGPPQYSDFASYHHVPGINNDPHHGQPAAAWGSPYTPAKEDWHSYGTAAASAATNPGQFGFSPPDFNPMQPHAGSGLLPPAISSSVPQLSPNAQRRTPYEWMRRSIPSTSSSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAALGLTERQVKIWFQNRRAKERKVNKKKLQQQSQPTSTTTPTPPAVGTPGPMGTLCSGSAPSLVSSSPLTIKEEFMP
Protein
Homeobox protein CDX-1: CDX1

Gene
Cdx1
Protein
Homeobox protein CDX-1
Organism
Rattus norvegicus
Length
123 amino acids
Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Similarity
Belongs to the Caudal homeobox family.
Mass
14.3 kDa
Fragment
single
Sequence
KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQQQQQQPMPPTQLPLPLDGTPTPSGHPGSLCPTNAGLLGTPSPVPVKEEFLP
Protein
Homeobox protein CDX-1: Cdx1