Cdc6

Cell division control protein 6 homolog

562 amino acids

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.

Belongs to the CDC6/cdc18 family.

62.614 kDa

MPQTRSQTQATIGFPKKKLSNTLKKPNSRDCEVKLRNVQPVPTTPCVDVKLLPLSPRKRLGDDNLCNTPRLSPCSPPKLGKKENGPPRSHTWKGCRLVFDDEPTFKASPPKEQDRVRQHQIRSSSAQRSPESKADPEQKCPPEKESVCIRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKSILLNCMSLRSAQAVFPAIAQEIGREELCRPAGKDLMRKLEKHLTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPSESPVPKRVGLAHISQVISEVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTRRLKIKEVTLGKLYEAYSSICRKQQVTAVDQSECLSLSGLLESRGLVGLKKNKESRLTKVSLKIEEKEIEHVLNGKAFTGNILAAGLP

CDC6

Cell division control protein 6 homolog

560 amino acids

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.

Belongs to the CDC6/cdc18 family.

62.72 kDa

MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP

CDC6

Cell division control protein 6 homolog

539 amino acids

May be involved in the initiation of DNA replication. May play a role in endoreduplication. Could act as one of the factors that contributes to maintain endoreduplication competence.

Belongs to the CDC6/cdc18 family.

59.841 kDa

MPAIAGPSSSPQKHVVGSRSESIGGVRSAEVNTSRKRKLISDSAAEVSATVVLPVNSISTPMKWKSPRRCAVSIPKTSDEEIKEDSNEKLENPVISVCLEVKSKWNPKDDEQMKAVKEALHVSKAPSTVVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSLSMEKVRLQAEEWAKQAGLHCPETVSVNCTSLTKSTDIFSKILGNYESGKKANGSFSPLQQLQRLFSQKQQQSRSKMMLIIADEMDYLITRDRGVLHELFMLTTLPLSRCILIGTVFCVINVHFLKSVSYGQTSFKFKVRICPPGVANAIDLADRFLPKLKSLNCKPLVVTFRAYSKDQILRILQERLVALPFVAFQSNALEICARKVSAASGDMRKALCVCRSALEILEIEVRGSIDQEPKGPVPECQVVKMDHMIAALSKTFKSPIVDTIQSLPQHQQIIVCSAAKAFRGSKKDRTIAELNKLYLEICKSSMITPAGITEFSNMCTVLNDQGILKLSLARDDKLKRVSLRVDEADITFALKEIRFFRNCLL

CDC6

Cell division control protein 6 homolog

515 amino acids

May be involved in the initiation of DNA replication.

Belongs to the CDC6/cdc18 family.

57.223 kDa

MPTLRSATASASTAGTASPTAIATPRSAKRRLTSPRRAAGSPDASQFTSPHKSPNVGIVGTPKLLSASPRSSRKRLYGDFVAAEKPKWNPRGKSPESHFSRAQSSDWDLTKEFICSADPAQMQVVKEALHVATVPSCGLVCRDDEQSRVLEFCKGCVEQERSGSLYVCGCPGTGKTLSINKVKESVARWADETGMETPDALSINCTSLAKTHEIFSKILAKFQTRKKATCKLSPLQQLQTMFSHKESAPRRMLLVVVDEMDYLITRDRAVLHDLFMLTTYQFSRCILIGIANAIDLADRFLPKLESLNCKPLVVTFRAYSKDQISDIIKHRLKVLEYDVFEPLALEFCARKVAAASGDMRKALGVCRSAVEVFEARLQESSDQEFGLVTFDHMDIALSKAFKSPVVDSILCLPQHQQMVLCALANTFHHCKKKATTLGELNKSYIEICRSTQVPAVGMLEFSNMCMVLSDQGFMKLGQSKEDKLRRVMLQIDSSDITFAFKGNRFFQKCLEQQKF

CDC6

Cell division control protein 6

513 amino acids

Plays a crucial role in forming the pre-replicative complexes. Interacts with the origin recognition complex (ORC) and MCM2-7 helicase complex leading to the linking of those complexes and loading of the replicative helicase MCM2-7 onto the pre-replicative complexes. Required for the initiation of DNA replication and then actively participates in the suppression of nuclear division.

Belongs to the CDC6/cdc18 family.

58.037 kDa

MSAIPITPTKRIRRNLFDDAPATPPRPLKRKKLQFTDVTPESSPEKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPDGRLESVAVTSINCISLGEPSSIFQKIFDSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLPTIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGSLNSAQVPLTPTTSPVKKSYPEPQGKIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLILCTIIQSLKLNSDATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKKTKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFLH

cdc6

ORC1-type DNA replication protein

430 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

48.096 kDa

MPETEDPATGLFIKYLSNNRIFRDREVLRHSYRPQILPHRQPQIDTIASILAPSLRNETPSNILIYGKTGTGKTASVRYVGSELEKASSTMGTTCRIVHLNCEVIDTQYRVLAQIAKCIDDVDEASSDKAKIHIPMTGWPTDQVYSELKNQLDTGGGVLVIVLDEIDKLVKKSGDDTLYNLTRINSDLKNSKVSIIGISNDLSFKDFLDPRVLSSLSEEEIVFPPYNAPQLVDILTQRAAGAFLDGAIADGVIPLCSALAAQEHGDARRALDLLRISGELADRDESKQVTDVHVKQAQAKIETDSMIECIATLPTQSKLILFSMLTLEQLGQNIFTSGEVSRVYQDIAPEIQLDILTHRRITDLISELNMLGVINTRVVSRGRYGRTKEMWFDANTGKIREVVLKDPRLNGLKDLDINQMETKWLKTWFR

cdc6

ORC1-type DNA replication protein

427 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

48.091 kDa

MSDDKTSPMGLFKKYLTNRRIFKNREVLRHNYRPQILPHRKPQIDEIASILAPALTNETPSNILIYGKTGTGKTASVRYVGTELENASALAGTKCKIVHLNCEVIDTQYRVLAQIANGLDNADEHPSDSTRSHIPMTGWPTDQVYMELKNQLESSGGVMVIILDEIDKLVKKSGDDTLYNLTRINSDLKFAKVSIIGISNDLRFTDFLDPRVLSSLSEEEIVFPPYNAPQLCDILQQRAEMAFVEGALDETVIPLCAALAAQEHGDARRALDLLRVSGELADRENASGVAEKHVRMAQEKIETDSMVECISTLPTQSKAVLYAMLILEQMGKRIFTSGEVTVVYREIARIIDLDVLTHRRITDLISELNMLGVINTRVISRGRYGRTKEMWFDAATSKIEEVVTRDPRLDDERLKKLDVNRLRAMFR

cdc6

ORC1-type DNA replication protein

425 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

47.379 kDa

MDSEPYKSTGLFKKYINPNKIFQNREVLRHSYSPKELPHRMDQIDSIAEILAPALQGATPSNILIYGKTGTGKTATVKFVGTELENESSEFSPCRLVHLNCETIDTQYRVLAQIANHVSGHDLKASDKIKNTIPATGWHTDQVYSELKNVLEQAGGLQIIVLDEIDKLVKKSGDDTLYNLTRINSDLFSSRVCIIGISNDLTFKDFLDPRVLSSLSEEELVFPPYNADQLRDILHQRAEMAFFPDVVSDEVIGLCAARAAQEHGDARRALDLLRVSGELAEREGAEHVMVKHVNSAQENIETDTMSECVKTLPSQSKIVLCSMLLMAASGQKVFTSGSVINVYREVAAELDTEALSHRRVSDLINELNMLGIITTRVVSHGRHGRTTEIYFKSPTNDIRTVIMNDSRFQECGILHPLLKSHEKGD

cdc6

ORC1-type DNA replication protein

424 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

47.966 kDa

MTQDMNDSPGLFDKYLSENRIFRDREVLRHSYRPHILPHRKPQIDQIAAILAPALQTETPSNILIYGKTGTGKTASVRYVGSELESVSARRGTVCRVIHLNCEVIDTQYRVLAQISKLIMGEDETPSDKIKTHIPMTGWPTDQVYSELKNQIELNSGVFIIILDEIDKLVKKSGDDTLYNLTRINTDLNRSKVSIIGISNDLGFKTFLDPRVLSSLSEEELVFPPYNAPQLCDILQQRAVIGFAEDALEDEVIPLCAALAAQEHGDARRALDLLRISGELADRENGSKVTVEHVKKAQAKIETDSMVECIRTLPTQSKIVLYCMLLLHRAGQRIFISGDVTRIYKELTPFLEIDVLTARRISDLISELNMLGVINTRLVNRGRHGRTKEMWFDTNTDKIWEVIMEESDGRLAQVDEQIVVQILR

cdc6

ORC1-type DNA replication protein

420 amino acids

Involved in regulation of DNA replication. May play essential roles in origin recognition and cell cycle control of replication. Binds specifically to the oriC region, which alters the topological structure of the DNA and introduces localized melting of the DNA duplex. May recruit the MCM helicase onto the oriC region. Shows weak ATPase activity in the absence of DNA.

Belongs to the CDC6/cdc18 family.

48.247 kDa

MNEGEHQIKLDELFEKLLRARKIFKNKDVLRHSYTPKDLPHRHEQIETLAQILVPVLRGETPSNIFVYGKTGTGKTVTVKFVTEELKRISEKYNIPVDVIYINCEIVDTHYRVLANIVNYFKDETGIEVPMVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLRDILTQRAEEAFYPGVLDEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWKAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGDVYAVYRELCEYIDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTSYKIRNVLRYDYSIQPLLTISLKSEQRRLI

cdc6

ORC1-type DNA replication protein

419 amino acids

Involved in regulation of DNA replication (By similarity). Binds specifically to the oriC region.

Belongs to the CDC6/cdc18 family.

47.93 kDa

MSEGEQLHLDKLFERLLKARKIFKNKEVLRHSYTPKDLPHRHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIPVEVIYINCEIVDTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLEEGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWRAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGDLPANTGEVYSVYRELCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYAIQPLLTVSLKGGQRRLL

cdc6

ORC1-type DNA replication protein

419 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

48.094 kDa

MNEGEQLHLDQLFEKLLKARKIFKNKEVLRHSYTPKDLPHRHEQIETLAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSHKYNIPVDVIYINCEIVDTHYRVLANIVNHFKHETGIEVPLVGWPTDEVYAKLKQVIDMRERFVIIVLDEIDKLVKKSGDEVLYSLTRINTELKRAKVSVIGISNDLKFKEYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAEEAFYPGVLDDGVIPLCAALAAREHGDARKALDLLRVAGEIAEREGASKVTEKHVWKAQEKIEQDMMEEVIKTLPLQSKVLLYAIVLLDENGELPANTGEVYSVYRDLCEYLDLEPLTQRRISDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKIRNVFRYDYTIQPLLAISLKDSQRRLV

cdc6

ORC1-type DNA replication protein

415 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

47.636 kDa

MDDDYLSSIFEKYLHARKIFKNKEVLRHSYTPKELPHRHKQIDDLAHILVPVLRGETPSNVFVYGKTGTGKTVTVKFVTEELKKISQKYNIPVEVIYINCEIIDTHYRVLARIVNHFKEESGIEVPLVGWPTDEVYAKLKEVIDAKERFVIIVLDEIDKLIKKSGDDILYSLTRINSELSKAKVSIIGISNDLKFKEYLDARVLSSLSEEEVVFPPYDANQLRDILMQRAKEAFYEGVLDDAVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVMLDENGELPANTGEVYSIYKMLCDSLDVEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYMVKNIYRHDEQVRPLLTLSLSRQRRLF

cdc6

ORC1-type DNA replication protein

415 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

47.541 kDa

MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSNVFVYGKTGTGKTVTIKFVTEELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREESGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKLIKKSGDDILYSLTRINTELHRAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLDDGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVLLDENGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQLQTVLTISMSRQRRLL

cdc6

ORC1-type DNA replication protein

410 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

45.602 kDa

MSITLQKQETDQDPVDAILDTAENGKSVIRNREMLRFTYIPETIHHRDGEQRNVTHSLSPILKRSRPSNLLVYGKPGTGKTLVVKKILQKIQERVKRSDFPIKLVYTNAKDETTLYGLLVSFGRQLGLDEKELPPTGLAISEVFKRLIKAIDTGRTNAVFVIDEIDYLAHLVSKTRKDVLYQLTRANERIREGSLTIVGISNDLAFKERLDPRVLSALSEEEVVFANYSVDQIRMILEDRAGEAFVPGAVSSSALNLCAAMAGREHGDARRAIDLLRVAGEMAERAAADGVTEGHVRDAALKIEENKENTALRSYPLHEKLVILAVMRSKGSSTGEIYSTYRELCRLTGQAVLTQRRATQMLSDVELSGMVSGRITHQGIHGRTKKFKLTVPPATVREAFGDDLILADII

cdc6

ORC1-type DNA replication protein

408 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

46.246 kDa

MDNPFIKYSRSDDYIIGNLKTLSSSYIPDNLPHREQQIELMARSLSSIMHGGIASNILLYGQSGSGKTSSAINVTNMLRSAAGDRVSIHYINCEIYDSHYSIMVHMVNSFIGEEQIPNLGLPFDRIYYELVKRIKSRNLYTLIILDEIDRLLSKNGSDSLYVILKLLGDTEGSIIGITNDSSFINKLDMRVRSRLNAESIIFTPYNADELRDILKFRINGVIKNGFIEDSAINLCAAIGAQEHGDARKAIELLRIAIEYCIRENRERVTIDDIYMARERFEMNILKESVKTLPIHSKMVLLSAILTQEVSSDIAVTGEIYENYKNICAEIGLQPLSTRRISDLMSSLDDLGLIVTTTRSMGRYGRTKLIKVSQPVAIKNYILEDENFKNFQGSRIVRQSKLRTNYDDI

cdc6

ORC1-type DNA replication protein

404 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

45.905 kDa

MDNPFSKFTNSRTIQADLSLLEENYIPDSFPHREKQINDMVTILSSIMRNSRPSNIIVYGKTGTGKTSTTKYVTRMLQEATSNVEVIYVNCEIYDSPYSILVYVANFAGGEKIPELGWPVDRIYREAVDRINGTGKFFVIVLDEMDRLIKKSGGDSLYVLLKLMTDVENVKVSMIGITNDTTLLENLDSRIKSRLNQESIVFPPYNATEIRDIIASRLEKVFGPGVVDDTAINLCAAIGAQEHGDARKAIDLMRIAIEIAIRENRLKVTEKEVYEARDKYEMNVMHEAINTLPIHSKIVLLSAIVTQEIEPNSVITGEIYENYRRICEDLGFTPLTPRRISDLLTELSDYGLIVVDERNMGKYGRTRGFSVVKEIETIKKYLMEDENLSMFKTSKMTKQARFDS

cdc6

ORC1-type DNA replication protein

394 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

44.774 kDa

MADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNVLIYGLTGTGKTVVVKYVVSKLKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRVPHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREGDDLIYKLVRANEELSKAKIVLIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVISYCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLPLHQKLVLKKIVELVEAKESTTTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLIISEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA

cdc6

ORC1-type DNA replication protein

384 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

43.978 kDa

MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYGKTGTGKTAVTLYAKKQLEEVAAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRGWTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDGDNILYTLTRTDNVAITSISNYIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALAAKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKVLESITYLTKKREEITSGRLYEVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRGKGRTNIITLQCDIELIDKALIYKD

cdc6

ORC1-type DNA replication protein

364 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

40.743 kDa

MFEKRPRLFKNRDVLSPLFVPDTLQDRKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVTTKYVINELEKHTSDAVIEYIVADGTAYQVATSIARAPRRGLGFLNIVEKIRERASEGKMIIVMDEIDKTLSRDGDKLLYHLSREPNVCIVGLSNKLTVMDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQRNGDARYALDLLSFAADIAIRQLKGVVSESDVRMATDEVEVEFIRRSIEQLRDNQKILLYAVMTSHGGTPTEIYRKYNKMTEEQFGGNALTQRRLSQLLRELELYGLVEIEVVGRGRGRGVNWHVVPSSSIDPELMLEAIRRSL

cdc6

ORC1-type DNA replication protein

364 amino acids

Involved in regulation of DNA replication.

Belongs to the CDC6/cdc18 family.

40.662 kDa

MFEKRPKLFKNRDVLSPLFVPDTLQDRKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVTTKYVINELEKHTSDAVIEYIVADGTAYQVATSIARAPRRGLGFLNIVEKIRERASEGKMIIVMDEIDKTLSRDGDKLLYHLSREPNVCIVGLSNKLTVMDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQRNGDARYALDLLSFAADIAIRQLKGVVSESDVRMATDEVEVEFIRRSIEQLRDNQKILLYAVMTSQGGTPTEIYRKYNKMAEEQFGGNALTQRRLSQLLRELELYGLVEIEVVGRGRGRGVNWHVVPSSSIDPDLMLEAIRRSL