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CCL11

Gene
CCL11
Protein
Eotaxin
Organism
Equus caballus
Length
100 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3 (By similarity).
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
11.247 kDa
Sequence
MKVSAALLCLLLTTAAFSTQVLAQPVSISTVCCFNVASRKISFQRLQSYRKITSSKCPQKAVIFKTKQAKKICADPKQKWVQDAMKYLDENSRTTKYSSF

Gene
CCL11
Protein
Eotaxin
Organism
Bos taurus
Length
97 amino acids
Function
Attracts eosinophils in vitro but is not responsible for eosinophilia in the ovary.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.965 kDa
Sequence
MKVSAVLLCLLLTATLCSIQVLAQPASIPTICCFNMSKKKISIQRLQSYRKITSSKCPQKAVIFNTKQNKKICVDPQEKWVQNAMEYLNQKSQTLKS

Gene
CCL11
Protein
Eotaxin
Organism
Homo sapiens
Length
97 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.732 kDa
Sequence
MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP

Gene
CCL11
Protein
Eotaxin
Organism
Macaca mulatta
Length
97 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3 (By similarity).
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.855 kDa
Sequence
MKVSTTLLWLLLVAAAFSPQGLTGPDSVATTCCFTLTNKKIPLQRLESYRRIISGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDRKSPTPKP

Gene
Ccl11
Protein
Eotaxin
Organism
Mus musculus
Length
97 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.893 kDa
Sequence
MQSSTALLFLLLTVTSFTSQVLAHPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEICADPKKKWVQDATKHLDQKLQTPKP

Gene
Ccl11
Protein
Eotaxin
Organism
Rattus norvegicus
Length
97 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.851 kDa
Sequence
MQLSTALLFLLLTATSFTSQVLAHPGSIPTSCCFTMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTKLGKEICADPKKKWVQDATKHLDQKLQTPKP

Gene
CCL11
Protein
Eotaxin
Organism
Cavia porcellus
Length
96 amino acids
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.
Similarity
Belongs to the intercrine beta (chemokine CC) family.
Mass
10.753 kDa
Sequence
MKVSTAFLCLLLTVSAFSAQVLAHPGIPSACCFRVTNKKISFQRLKSYKIITSSKCPQTAIVFEIKPDKMICADPKKKWVQDAKKYLDQISQTTKP