CCC2

Copper-transporting ATPase

1004 amino acids

Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone ATX1 and incorporates it into trans-Golgi vesicles.

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.

109.829 kDa

MREVILAVHGMTCSACTNTINTQLRALKGVTKCDISLVTNECQVTYDNEVTADSIKEIIEDCGFDCEILRDSEITAISTKEGLLSVQGMTCGSCVSTVTKQVEGIEGVESVVVSLVTEECHVIYEPSKTTLETAREMIEDCGFDSNIIMDGNGNADMTEKTVILKVTKAFEDESPLILSSVSERFQFLLDLGVKSIEISDDMHTLTIKYCCNELGIRDLLRHLERTGYKFTVFSNLDNTTQLRLLSKEDEIRFWKKNSIKSTLLAIICMLLYMIVPMMWPTIVQDRIFPYKETSFVRGLFYRDILGVILASYIQFSVGFYFYKAAWASLKHGSGTMDTLVCVSTTCAYTFSVFSLVHNMFHPSSTGKLPRIVFDTSIMIISYISIGKYLETLAKSQTSTALSKLIQLTPSVCSIISDVERNETKEIPIELLQVNDIVEIKPGMKIPADGIITRGESEIDESLMTGESILVPKKTGFPVIAGSVNGPGHFYFRTTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNISANPPVAFTANTKADNFFICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFDKTGTLTTGFMVVKKFLKDSNWVGNVDEDEVLACIKATESISDHPVSKAIIRYCDGLNCNKALNAVVLESEYVLGKGIVSKCQVNGNTYDICIGNEALILEDALKKSGFINSNVDQGNTVSYVSVNGHVFGLFEINDEVKHDSYATVQYLQRNGYETYMITGDNNSAAKRVAREVGISFENVYSDVSPTGKCDLVKKIQDKEGNNKVAVVGDGINDAPALALSDLGIAISTGTEIAIEAADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNLFWALCYNIFMIPIAMGVLIPWGITLPPMLAGLAMAFSSVSVVLSSLMLKKWTPPDIESHGISDFKSKFSIGNFWSRLFSTRAIAGEQDIESQAGLMSNEEVL

CCC2

Cation-chloride cotransporter 2

994 amino acids

Probable cation/chloride cotransporter.

Belongs to the SLC12A transporter family.

109.326 kDa

MERGGFGGAGRHDEEAPAMRPAPQQRYRTVESHDRAVVQMAPMEFGSSADASASAGPRYIKPGTNLRTDARMHMASSNGRSSNGSQGDSKLELFGFDSLVNILGLKRMVGEQAQASASTRDGENAGIAIGHPKETETKLDTMMGVFVPCLQNILGIIYYIRFTWIVGMGGVWQSLVLVAFCGSCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGLCFFLGNAVAGAMYVLGAVETFLDAVPSAEFFQESVTVVTNTFVNGTAAGNATTISTPNLHDLQVYGIIVTILLCFIVFGGVKIINKVAPAFLIPVLFSILCIYIGVFIAPRPNASKWITGLSITTLKDNWSSDYQRTNNAGVPDPNGSIYWDFNALLGLYFPAVTGIMAGSNRSASLKDTQRSIPIGTLHATISTTMMYLLSVFLFGALSTREGLLTDRLLCAAVAWPSPAVVYAGIILSTLGAALQSLTGAPRLLAAIANDDILPVLNYFKAYEGSEPHVATLFTSFICISCVIIGNLDVITPTITMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKLHHWSLSLIGALLCIVIMFMISWTFTVVSLALASLIYYYVSLKGKAGDWGDGFKSAYFQLALRSLRSMGANQVHPKNWYPIPLIFCRPWGKLPEDVPCHPKLADFANCMKKKGRGMSIFVSIIDGDYHESAEDAKTACRQLSAYIDYRRCEGVAEIIVAPSTSIGFRSIVQTMGLGNLKPNIVVMRYPEIWRRENLTQIPSTFVSIINDCITANKAVVIVKGLDEWPNEYQRQYGTIDLYWIVRDGGLMLLLSQLLLTKESFESCKIQVFCIAEEDTEAEELKADVKKFLYDLRMQADVIVVTVKSWEADPDRSGGSKKDDPEVYRSAQSRIRTYISQLKEAAERERRPLMEGGKQVVVDEQKVEKFLYTMLKLNATILRHSRMAVVVLVSLPPPPLNHLAYCYMEYMDLLVENIPRILIVRGYRRDVVTLFT

ccc2

Copper-transporting ATPase ccc2

904 amino acids

Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone atx1 and incorporates it into trans-Golgi vesicles (By similarity).

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.

97.895 kDa

MYTTTLSVQGMTCTSCVASIQSMLEGVEGIEQFTISLLLERAIAVHDPSIISPDQIAEKIEDCGFDASVISSTEGEHGVMANYLLLSPMQAEQWTKVHNHINELQGVLSVNCSSSPDAAIRVIYDSEITGPRSIMKEILSMGVKCTFQPVDSSTSRILSLQRGSQIRVWKIRFIISISFSLAVMFLPQIFDSCDSMRAAFLVPHYFGICAGHIISLVLSLPVQFGVGRVYYSAAYHALKRGTANMDVLVSLGSTVAFAASIFFMILYSARHADNPAPIFFDTADMLLTFVTLGRYLESKAKGSTSAALSQLLSLAPSSATIIEDNEQIEILADLIERGDLILVKPGEIIPVDGTVVEGSSYVDESSVSGEPVPVHKTIDDELLSGTANGNGRLLVKATKSPRESQLAVIVDLVQRAQISHAPIQQFADRVAGIFVPVIVALSISTFTFWFLFTKYSSKYPSVFDDPMGKFAVCLKLTISVVVVACPCALGLSTPTAVMVGTGVGALNGIIIKGGEILERLNQVDTVVFDKTGTLTVGKLSVTDISIVDNLEELLDIPKNIFWAFVKASESSSEHPIGKAITEKASEFTDVSEIGIESFNAVPGEGVDVVLRWKERTFHALLGNSLLLEHNNVSIPDDFDSKLKLSSSSGLTCVRIAIDGQFVGFLGCMDQVRPDSYQTVSALKQLGKKVCLLTGDQKATARRVAQGLEIDFSDVYAEAVPSQKAEIIQKLKDQKHCVAMVGDGINDSPSLVLADVGIAPINGSGIALESADVILVRKGVLLDTAVSFDLSRVIVKRIKMNLVWACIYNFVMIPIAMGFFLPWGIYLNPMWASAAMMFSSLSVLASSLLLRRWKKPKSLIFSEADDVETESSTNSSVLQKVYTATRSIFGRNKSSNKYQPVANEV