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BRK1

Gene
BRK1
Protein
Protein BRICK 1
Organism
Arabidopsis thaliana
Length
85 amino acids
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Similarity
Belongs to the BRK1 family.
Mass
9.481 kDa
Sequence
MAKAGGITNAVNVGIAVQADWENREFISHISLNVRRLFEFLVQFESTTKSKLASLNEKLDLLERRLEMLEVQVSTATANPSLFAT

Gene
BRK1
Protein
Protein BRICK1
Organism
Zea mays
Length
84 amino acids
Function
Promotes multiple, actin-dependent cell polarization events in the developing leaf epidermis. Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Similarity
Belongs to the BRK1 family.
Mass
9.324 kDa
Sequence
MGRGGGMGNPVNVGIAVQADWENREFISNISLNVRRLFDFLLRFEATTKSKLASLNEKLDILERKLEVLEVQVGSATTNPSVFN

Gene
brk1
Protein
Probable protein BRICK1
Organism
Danio rerio
Length
75 amino acids
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
Similarity
Belongs to the BRK1 family.
Mass
8.731 kDa
Sequence
MAGQEDPVQREIHQDWANREYIEVITSSIKKIADFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT

Gene
BRK1
Protein
Protein BRICK1
Organism
Homo sapiens
Length
75 amino acids
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Similarity
Belongs to the BRK1 family.
Mass
8.745 kDa
Sequence
MAGQEDPVQREIHQDWANREYIEIITSSIKKIADFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT

Gene
Brk1
Protein
Protein BRICK1
Organism
Mus musculus
Length
75 amino acids
Function
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).
Similarity
Belongs to the BRK1 family.
Mass
8.761 kDa
Sequence
MAGQEDPVQREIHQDWANREYIEIITSSIKKISDFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT

Gene
brk1
Protein
Protein BRICK1
Organism
Dictyostelium discoideum
Length
68 amino acids
Function
Involved in regulation of actin and microtubule organization.
Similarity
Belongs to the BRK1 family.
Mass
8.198 kDa
Sequence
MSTKTNIQKDWEQREFIEDMSINIQKIVEFLNKFELSTRNKLSDLNEKLTILDRQVDYLEATFKTVQE