Protein
Apoptosis regulator BALF1
Organism
Epstein-Barr virus (strain GD1)
Function
May play a role in host B-cell survival by preventing host apoptosis. The survival of infected B-cells is a key step to induce host cell differentiation into memory cells, thereby assuring long term infection of the organism. May also play an active part in oncogenesis in Burkitt's lymphomy and nasopharyngeal carcinoma (By similarity).
Similarity
Belongs to the Epstein-Barr virus BALF1 family.
Sequence
MNLAIALDSPHPGLASYTILPRPFYHISLKPVSWPDETMRPAKSTDSVFVRTPVEAWVAPSPPDDKVAESSYLMFRAMYAVFTRDEKDLPLPALVLCRLIKASLRKDRKLYAELACRTADIGGKDTHVRLIISVLRAVYNDHYDYWSRLRVVLCYTVVFAVRNYLDDHKSAAFVLGAIAHYLALYRRLWFARLGGMPRSLRRQFPVTWALASLTDFLKSL