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Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila grimshawi
Length
1011 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
114.437 kDa
Sequence
MAESDDEYDRKRRDKFRGERDSYRPERRDDRRPMGGGAGNARDEWAERNPFRGSAAAGGGGGGGGVGGGGGARHRPDYSDYRGSGPRPRYGSPGREMPPAKRMRPDWGDGEMRANPRFGYDPYLVQAWNDHYQSLHSAYSHSGHAPSAREPPPSGISNSDTQTQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSDEQRGFLKRRTDVFLELLNNGTISNVKVDSSQADALVRVLDTCVIKLEGGTDEDLKILDEKPKDPAPVYERRSERSERSEATESVVVTKREPESPKHQTKSEKDDDDLPEVESPQRKNVRPVNSDDEDWDDDEEMPAAKSEQQSELAAEKPAKQLNDEESMQANIDKNQKKSKKRKRTSSDDESSSSSSSESDSDSDDEKLIEKYDVEEGLRADQKAEAEKDKEEEEERAATAAAKAKQLPPDSPTPDEDVDAAAVEEQKNEVVAIKTEVNDEESQKTEQPAAEEEKSEQPKDDPEASSKNGEENEEEKAEKSEADTATTKAAAAAADDDAMTETIDVDKLKDSLKPRALHRTSSIFLRNLAPSITKAEIETICTRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQIVRSDIKLCAKIAMNLDERFKLWSEVDNADNAELNPEELKEATNGSGSYGFNSKNPVLQNITDYLIEEASAEEEELLGLAGDSKDGEGEPIERDEPLIQVLDRLVLYLRVVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPMRVTSNDVQEYIKSYEGKLQQFLAKTVQLSDENIKELGAKNPEKEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSSKRTESESGRGSGGYRPPMYPPFSAMPYGFAPPMMGGGGRGGRNFPQARREMPVEHQRRLIGYHDLDAPVNSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila willistoni
Length
1000 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
113.364 kDa
Sequence
MADSDDEYDRKRRDKFRGERSDSYRTERRDERRPISSSGGARDEWNPFRGSSAAGGGGGGGARHRPDYSDYRSPGGGGPRARYGSPGREMPPAKRMRPDWPDEGMRSNPRFGGYDPYMMQAWNEHYQSLHYSHGGGHMPIARETSGPGIGNDTQTQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSDEQRGFLQRRSSVFVELLENGTIGSVKVDSSQADPLVRVLDMCVIKLEGGTDEDLKILDEKPKEPLVFERKIEPIQTTAALAAATATPKSPKKNENDNGVAVVVSPQKNDLKPVNSDEENWETDKKSDENDKNDNEQGDGDKKGGESSKKQLKKKKKTKKRKRKSSDDDDDESSSSDSESSSSSEEEEDEEELKKKYDVEDGLRTEQKAEQEKDKKEEEAIKAANVEEQPKAEEVQEKIEDEKEKVEEEPKPDVKTEAEAVAEPDAEPKKEEEEKAKEPEDEEKKPETEETSKMETENGESKEETKPTPEPAVESAPAADVIEMETETIDLDKVKDGPQPRALHRTASIFLRNLAPSITKAEIEAICNRSPGYLRVAIADPLVERRWYRRGWITFSRDVNIKEICWSLNNQRLRDCELGAIVNRDLSRRVRPTNGITAHKQVVRSDIKLCAKIAMNLDERFRLWVDEPAPAADGKGETATDATNGSSSGATTYGFNTKNPVLQNITDYLIEEASAEEEELLGLSGDQNDVEGEPIVRDEQLIAVLDRLLLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPMKVTSNDIQEYIKSYEGKLQQFLTKTVLLTDDDIKDLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQFFNNYLRDPKRPQLPEHPGTTKRPEFEPSRGAGGYRPAMYPPFGGLPYGFAPPMPMGGRGGGRGYQARRELPLEHQRRVIGYHDLDAPANSDRENAF
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila mojavensis
Length
980 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
110.954 kDa
Sequence
MADSDDEYDRKRRDKFRGERDSYRPERRDERRPMGGAANSRDEWSERNPFRGSSAAGGGGGGGGARHRPDYSDYRGSGPRARYGSPGREMPPAKRMRPDWGDSEMRSNPRFGYDPYLVQAWNDHYQSLHSAYSHAGHGPSVRETGPAGGGGVSGDTQTQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSEEQRGFLKRRTEVFLELLENGTIGSVKVDSSQADALVRVLDTCVIKLEGGTDEDLKILDEKPKDPPIVYERKSETTESAVVAKREPESPKTEKDDDLPGASSPQHKSLRPVNLDEENWDEDEPMEVHPQTGKDGEKSDDRRSKEPEDEESVKSDNEKKLKKKKIKKRKRNSSDDDSSSSSSSDSDTESDDEKVKAKYDVEEGLRADQKAEALKDKEEAATAAKEKLLAPESPQPEDVVDPKEALEIKSEASEESKQDKTEQPVGQTERPTTDNPAEKNGEEEGAKAEDKPEAGTQESTANEVTETIDLDKVKDGPHPRALHRTSSIFLRNLAPSITKAEIEAICKRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQIVRADIKLCAKIAMNLDDRFKLWCDSNRSDAEDAEKKAGQEATNGSGASSSPSYGFNSKNPVLQNITDYLIEEASAEEEELLGLAGDNKDGDGEPIERDESLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPMRVTSNDVQEYIKAYDGKLQQFLTKTVQLSDEEIKELGAKNPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVEEVRKEVQYFNNYLRDPKRPQLPEHPGSSKRTESESGRGSGYRPPMYPPFSAMPYGFAPPMMGGGGRGGRNFPPVRREMPLEHQRRIIGYHDLDAPINSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Anopheles gambiae
Length
967 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
109.612 kDa
Sequence
MGDSDDEYDRKRRDKFRGERSAGGGGDSYGRGADRPDRSRGRDDWPDRVRPRQDYRDYRPPPRDRGYSPAREGPTVKRMRGDTWGDEGRHRFGAHDGYGMYGYAHDHFGMHPTVGPYGHQHATHQREPVVSGDMQTQPCMMTLKQFLATQDDSISDSDAITKYNEYKLEFRRQQMNEFFVAHKDEEWFKIKYHPEESQKRKEEQLSFLKRRCEVFLELLKSKEIGKVSVDASNTDALLRLLDTVVIKLEGGTEEDLKVLDIKPSVVEAAARTPATLNEEKVKTESKVDATAKELAVKMEEDSSKQETETDVLSVPQSEEDARNGNSKIKEELSKSMDDGNENGDKSKSNDAQKSEKEIAEVEHEAHKHESEDRKKRSRSDSGSSSSSSSSSSSSESEEEKDERMNKEDNEDEENMRIPEEEKKSDSADTMDNINRDKEVDEGKPVCDAEDLNTADDRDDNADQNKEQNEFEETTKDKNSSDPVNDENKENSDKKSQQEGDSKAETIDLAKDPADGGSRALHRTSSIFLRNLAPSITKAEVEAMCRRYNGFLRVAIADPLLERRWFRRGWVTFKREVNIKEICWNLNNIRLRDCELGAIVNKDLSRRVRPVNGITCHKTVVRSDIKLGAKIAHNLDDKWGLWKETPTAASGTGEAGDKNGSEVQPEESFGLQSKNPVLQNITDYLIEEASAEEEELLGLSEDSKKVSEGELIERDPQLIEVLDRLILYLRIVHSVDFYNHCEYPYEDEMPNRCGIIHARGPPSQSKVMSNEIQEYIRTFEGKMASFLTRMVDIDETDMKKLGAKDAEAEVEKFITANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHAEKVEEVRKEVEYFNNYLKDSKRPQLPEHPGNAKKPGSEGATSATANASVGAGGYRNQPFGMSHSYAPMYASYAAASMMAPNPRGRAGFGRGGRMGGPDYRPVIHYRDLDAPREPDEFL
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila virilis
Length
963 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
109.044 kDa
Sequence
MADSDDEYDRKRRDKFRGERDSYRPERRDERRPMGGGANSRDEWSERNPFRGSSAAGGGGGGGARHRPDYSDYRGSGPRPRYGSPGREMPPAKRMRPDWGESEMRSNPRFGYDPYLVQAWNDHYQSLHSAYSHSSHPSSARESAPNVVNSDTQTQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSEEQRGFLKRRTDVFLELLENGTIGSVKVDSSQADSLVRVLDTCVIKLEGGTDEDLKILDEKPKETPVVYERKSESTEASVVAKREPESPKQTKSEKGADEEQPVVVSPQRKSLRPVNSDEENWDDENDEMAAPAKVQGDDDSIKSGSDKKLKKKKIKKRNRNSSDDESSSSSSFESDSDSDDEKLKAKYDVEEGLRADQKAEAQKDKEEAATVAKANPLPPDSPQPEGGTALQDAAAIKSEQSDEQQEKDAEQPAELQADEPAAAKNGEEPEKTEKNEVETKSTADDVTETIDLDKVKDGPQPRALHRTSSIFLRNLAPSITKAEIEAICTRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQIVRADIKLCAKIAMNLDERFKLWSEADSTQQQPDAESKPSADATNGSGGSSTTYGFNSKNPVLQNITDYLIEEASAEEEELLGLAGDNKDGEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPMRVTSNDVQEYIKAYDGKLQQFLTKSVQLSDDEIKELGAKNPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSSKRTESESGRGSGGYRPPMYPPFSAMPYGFAPPMMGGGGRGGRNFPPVRREMPLEHQRRLIGYHDLDAPVNSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila persimilis
Length
951 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.855 kDa
Sequence
MADSDDEYDRKRRDKFRGERESYRTERRDERRPIGGAGGGRDEWSERNPFRGGGAGGGGAPRHRPDYSDYRGPGPRARYGSPVRDMPPPKRMRSDWGDGDGRPGPRYGGYDPYLMQAWTDHYQSMHSAYHHASHPPPVRELPIIGGDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVNRSEEQRGFLRRRTDVFVELLENGTIGSVKVDSSHGDALIRVLDTCVIKLEGGTDEDLKVLDEKPKEALVFDRKPESVDPTTVVENTPKSPKKEKEEDELPLIVSPQRIALKPVNSDDENWDDAEVEDAPPKKPEEEEPKESEPIPEIKQKQKKEKKKKIKKRKRNSSSDEESSSSESESSSSSSEEEEEDDEKLKAKYDVEDGLRAEQKAEAEKDQAEAAKAKLGSVSPKEEISPEKSAADPEVEGEAKEDGKQAEKSPKSDDEKKQENGDAAKVESAAEPATGDAQGEVKPVTIDLDKVNPPRDMHRTSSIFLRNLAPSITKAEIEALCSRFSGYLRTAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCARIVMNLDEKFKLWSEGPLSKPSPASDSEATAANGSGSSYGFNSKNPVLQNITDYLIEEASAEEEELLGLSGDRKDGEGEPIERDEQLLSVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPSRVTSNELNEYIKSYEGKLLQFLTKTALLSEDQIKDLGAKNADTEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSVKRPETESVRGPGGYRPPMYTPMSGMPYSFGGHMMGGGRGGRHFPPARRELPLEHHRRLVGYHDLDAPSNSDIFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila pseudoobscura pseudoobscura
Length
951 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.827 kDa
Sequence
MADSDDEYDRKRRDKFRGERESYRTERRDERRPIGGAGGGRDEWSERNPFRGGGAGGGGAPRHRPDYSDYRGPGPRARYGSPVRDMPPPKRMRSDWGDGDGRPGPRYGGYDPYLMQAWTDHYQSMHSAYHHASHPPPVRELPIIGGDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVNRSEEQRGFLRRRTDVFVELLENGTIGSVKVDSSHGDALIRVLDTCVIKLEGGTDEDLKVLDEKPKEALVFDRKPESVDPTTVVENTPKSPKKEKEEDELPLIVSPQRIALKPVNSDDENWDDAEVEDAPPKKPEEEEPKESEPIPEIKQKQKKEKKKKIKKRKRNSSSDEESSSSESESSSSSSEEEEEDDEKLKAKYDVEDGLRAEQKAEAEKDQAEAAKAKLGSVSPKEEISPEKSAADPEVEGEAKEDGKQAEKSPKCDDEKKQENGDAAKVESAAEPATGDAQGEVKPVTIDLDKVNPPRAMHRTSSIFLRNLAPSITKAEIEALCSRFSGYLRTAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCARIVMNLDEKFKLWSEGPLSKPSPASDSEATAANGSGSSYGFNSKNPVLQNITDYLIEEASAEEEELLGLSGDRKDGEGEPIERDEQLLSVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPSRVTSNELNEYIKSYEGKLLQFLTKTALLSEDQIKDLGAKNADTEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSVKRPETESVRGPGGYRPPMYTPMSGMPYSFGGHMMGGGRGGRHFPPARRELPLEHHRRLVGYHDLDAPSNSDIFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila ananassae
Length
948 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.63 kDa
Sequence
MADSDDEYDRKRRDKFRGERSDSYRTERRDDRRPLGGSGSARDEWSDRNPFRGGASAGGGGGGARHRPDYSDYRGPGPRARYGSPGRDLPPAKRMRPDWGDGDVRPNPRFGGYDPYLMQAWNDHYQSIHSAYSHGSHMPPVRESGGSGGDSLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRAEEQRGFLKRRTDVFVELLENGTIGSVKVDSVQGDALIRVLDTCVIKLEGGTDEDLKALDEKPKETPVYERKHDPAPVKAVDEVKSPKKETEKEASPVIVSPQRKSVKPLNSDDENWDEEVAAPPKKDVEEEPKALESGSEDKSRRKKSAKRKRVNSGDDSSSESDSSSSSDDEDEEKLKKKYDVEDGLRSEQKAEAEKDKEMQDAKVIEAPESPKEATENSAEEVKASDAAETPAEEAEQEKPEVAEEVNRPKQDQENGDKITTEDGETKSDSEENKVMETETIDLDKVRDGQPRALHRTSSIFLRNLAPSITKAEIEAVCTRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIILNLDERFRLWPEPTSDDSIPFDRAGESSANGNTSTYGIKSKNPVLQNITDYLIEEASAEEEELLGLTGENKDAEGEPIERDEHLLAVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPSRVTSNDIHEYVKTYESKLQQFLTKTALLSDEETKDLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSSKRPESESGRGGGSGYRPPMYPPFSGMPYGFSPSMMGGGRGGRNFPPVRRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila erecta
Length
947 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.71 kDa
Sequence
MADSDDEYDRKRRDKFRGERSDSYRTERRDDRRPVGGSAGARDEWAERNPFRGGASAGGGGARHRPDYSDYRGPGARPRYGSPGRDLPPAKRMRPDWGDADLRPNPRFGGYDPYLMQAWNDHYQSMHSAYSHAGHAPPVRESIGGGGDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSDEQRGFLQRRTDVFVELLENGTIGSVKVDSSQGDALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVCERKAEPIESAKAVEKTINSPKEEKISEGDPLPAIVSPQRKTVKSVNSDEENWDDEDAENATPKKELGEDSKGTDSKPEDKQLNKKKTKKRKRNSTDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKADAEKDRHEATKAKQEPESPKLQELEGKEIVEPKELDSKSNTAENDDTLKSPEISPTPIKGTDNGDDNKVEEDEKKPSVDEIKVVETETIDLDKVKNGQPRALHRTSSIFLRNLAPSITRAEIETVCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNHRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDERFRLWAEVPTDDSHPSRADESTENGSGSTYGFNSKNPVLQNITDYLIEEASAEEEELLGLTGENKDTDGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPVRVTNNDVQEYIKTYESKLQQFLTKTVLLSDEEIKDLGAKDPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRTESESARGGGGGYRPPMYPPFSAMPYGFGPPMMGGGRGGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila sechellia
Length
947 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.857 kDa
Sequence
MADSDDEYDRKRRDKFRGERDSYRTERRDDRRPVGGSAGARDEWAERNPFRGAASAGGGGARHRPDYSDYRGPGARPRYGSPGRDLPPAKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHAGHAPPVRESIGGGGSDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTDYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRNEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEPMQSVKEVEKTINSPKDEISEADPLPAVVSTQRKPVGPVNSDEENWDDDNDAENSTPKKELAEDSKDSDSKPEEKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRTEQKIEAEKDRQEATKAKQEPQSPKLDEVEGNDTTEPKGLDSKINTVEIDDTLKSPEISSNPIKNTDNGDSSKVEEDEEKPSVGKDKVVETETIDLDKVKDCQPRALHRTSSIFLRNLAPSITRSEIEAMCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEVPKDDPNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRVTNNDVQEYIKMYETKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYRPPMYPPFSAMPYGFGPPMMGGGRGGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila simulans
Length
947 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.813 kDa
Sequence
MADSDDEYDRKRRDKFRGERDSYRTERRDDRRPVGGSAGARDEWAERNPFRGAASAGGGGARHRPDYSDYRGPGARPRYGSPGRDLPPAKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHAGHAPPVRESIGGGGSDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELFENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEPMQSVKAVEKTINSPKDEITEADPLPVVVSTQRKPVGPVNSDEENWDDDNDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRTEQKIEAEKDRQEATKAKQEPQSPKLDEVEGNDTTEPKGLDSKINTVEIDDTLKSPEISSNPIKNTDNGDSSKVEEDEEKPSVGKDNVVETETIDLDKVKDCQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFNGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEVPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRVTNNDVQEYIKMYETKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYRPPMYPPFSAMPYGFGPPMRGGGRAGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila yakuba
Length
944 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.503 kDa
Sequence
MADSDDEYDRKRRDKFRGERSDSYRTERRDDRRAVGGSTGARDEWAERNPFRGGASAGGGGARHRPDYSDYRGPGARPRYGSPGRDLPPAKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAFSHAGHAPPVRESIGGGGSDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFVELLENGTIGSVKVDSSQGDALIRVLDTCVIKLEGGTDEDLKVLDEKPKDLVVYERKTEPMESVKAMEKAISSPKEEKIREEDPLPAVVSPQQKTARSVNSDEENWNDEDAVTKKDLGEHSKDTDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKAEAEKDRQEAAKAKQEPESSKLEELVGKEITEPKELDSKINTVENDDTLKSPEMTPNPIKRTDNGNGNKVEDEEKPSVDENKVVETETIDLDKIKDGQPRALHRTSSIFLRNLAPSITRAEIEAVCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGLTAHKQVVRSDIKLCAKIALNLDERFRLWAEVPTDDSNSARADESSENGSGSTYGFNSKNPVLQNITDYLIEEASAEEDELLGLTGENKDTEGEAIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPVRVTNNDVQEYIKTYESKLQQFLTKTVLLSDEEIKDLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHDEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYRPPMYPPFSAMPYGFGPPMMGGGRGGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Drosophila melanogaster
Length
943 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha.
Similarity
Belongs to the ARS2 family.
Mass
107.222 kDa
Sequence
MGDSDDEYDRKRRDKFRGERESYRTERRDDRRPVGGSAGARDEWAERNPFRGGASAGGGGARHRPDYSDYRGPGARPRYGSPVRDLPPAKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHGGHAPPVRESIGGGGGDTLTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYRPPMYPPFSAMPYGFGPPMMGGGRGGRNFPPARRELPLEHQRRLIGYHDLDAPANSDMFD
Protein
Serrate RNA effector molecule homolog: Ars2

Gene
Ars2
Protein
Serrate RNA effector molecule homolog
Organism
Aedes aegypti
Length
937 amino acids
Function
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex (By similarity).
Similarity
Belongs to the ARS2 family.
Mass
107.294 kDa
Sequence
MGDSDDEYDRKRRDKFRGERSAGESYARGADRADRSRGRDEWAERGRPRQDYRDYRPPPRDRGYSPTREGPPMKRMRGDGWGDDARPRFGGHEPYGMYGGYNHDHFGMHPAGPYGHPGGLHPREQQSAGDMQTQPCMMTLKQFLATQDDSISDSEAIQKYNDYKLEFKRQQLNEFFVAHKDEEWFKMKYHPEESLKRKEEQFGFLKRRCDVFVELLDHGDISKVSVDTSNTDPLLRLLDTVVIKLEGGTDEDLKVLDEKPVEIVKILPEKPKVEVKKEPTLEDTIKKEKISIKEEKVEEADKPKEEKDDDKEKPAAEGEEPEGEKNDAEKEVTAEREDMDAEPAAKEPEPEEEPSRKKDRRKRSRSDSGSSSSSSSSSSSSDSEDEKEKEKEDKEEEEEKKETEEEAAPKSPKPVEEGEKEPQEEVENNGHKSGDEEEATKKDQAEPEKMDTDEAVVENNKESEEAEKEKDTSKDEEEANKESNEDKQESEKTETIDLVKDTTVGNSPRALHRTSSIFLRNLAPSITKAEVEAMCKRYNGFLRVAIADPLLERRWFRRGWVTFRRDVNIKEICWNLNNIRLRDCELGAIVNKDLSRRVRPVNGLTCHKTIVRSDIKLCAKIAHNLDDKVGLWKEQEDNGEKNGESFGLQSKNPVLQNITDYLIEEASAEEDELLGLSTEAAKKSNDGELVERDTQLIEVLDKLILYLRVVHSIDFYNHCEYPYEDEMPNRCGIIHARGPPPQNKVTSNEIQEYIRTFEGKMGSFLARAVDLEEEEMKKLGAKDAEAEVEKFIQANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHNEKVDEVRKEVEYFNNYLKDTKRPQLPEHPGNTKKAPSDAAPPTAGYRPPYGMAHAYAPMYAPYAQPMMAPAGRARPGFGRGGREPMGEIRRPIIAYSDLDMPNFSDSFL
Protein
Serrate RNA effector molecule homolog: Ars2