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Arc2

Gene
arc2
Protein
Actin-related protein 2/3 complex subunit 2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
317 amino acids
Function
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).
Similarity
Belongs to the ARPC2 family.
Mass
36.974 kDa
Sequence
MLSLDYNNIFIYELLTERFSSENPSSIDQVVTDFDGVTFHISTPEEKTKILISLSMKCYPELVNYGTLDLLKQIYGAYVHEPEMGYNFSILIDLQQLPATDEEKEQLAMSISMLKRNVLAAPFHRAFTKQAELADLARKDPENAPMLDKQATSQELMAIHYRDEETIVLWPEHDRVTVVFSTKFREETDRIFGKVFLQEFVDARRRPAIQTAPQVLFSYRDPPLEIRDIQGIQKGDDFGFVTFVLFERHFTPQNREDCISHIQVFRNTLHFHIKASKAYMHQRMRKRVADFQKVLNRAKPDVELERKTATGRSFVRA

Gene
ARC2
Protein
Arcelin-2
Organism
Phaseolus vulgaris
Length
265 amino acids
Function
Seed storage. This carbohydrate-binding lectin has toxic effects on bean bruchid pests. Antibiosis properties of legume lectins are proposed to be due to the lysis of epithelial cells of the intestine by binding to the carbohydrate moieties of these proteins.
Similarity
Belongs to the leguminous lectin family.
Mass
29.275 kDa
Sequence
MASSNLLTLALFLVLLTHANSSNDASFNVETFNKTNLILQGDATVSSEGHLLLTNVKGNEEDSMGRAFYSAPIQINDRTIDNLASFSTNFTFRINAKNNENSAYGLAFALVPVGSRPKLKGRYLGLFNTANYDRDAHTVAVVFDTVSNRIEIDVNSIRPIATESCNFGHNNGEKAEVRITYYSPKNDLRVSLLYPSSEEKCHVSATVPLEKEVEDWVSVGFSATSGSKKETTETHNVLSWSFSSNFINFEGKKSERSNILLNKIL

Gene
Arc2
Protein
Activity-regulated cytoskeleton associated protein 2
Organism
Drosophila melanogaster
Length
193 amino acids
Function
Self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer. Arc2 protein is released from cells in extracellular vesicles that mediate the transfer of mRNA into neighboring cells.
Similarity
Belongs to the ARC/ARG3.1 family.
Mass
22.622 kDa
Sequence
MTQMSDEQFRIFIETIKSLGPIKEEPPSKGSFSNCTVRFSGQRDHDAVDEFINAVETYKEVEGISDKDALKGLPLLFKSIAVVWWKGVRRDAKTWSDALQLLRDHFSPTKPSYQIYMEIFETKQSYDEVIDSFICKQRALLAKLPEGRHDEETELDFIYGLMQPKYRESIPRHEVKTFRELLDRGRTVERTRH