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ATG17

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
557 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
61.445 kDa
Sequence
MSSSESSSASGGGPPDAEPSQTEQQTMPQLDTLISHLVAAKRSLSSINHVWRANEIVTTARAALEESVVVSARTGFLRRGLNNQLRLLYSVRTEVEEISLRGRSEFAAVLKDLDAADARLRRTLELLRETIVHGGFRPEGEQPRSLHDFVDERGVEELHAALKNSIDRTNGAQAQLDSSNHAFDDELLSIKEALGNYRAVAKLASSRSSSSPSSSSASNSSLPSMSSMPSMLHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAAKSITGDMHVGVNASGRIGPNIEEGINANLNAPLDPLSDSEYREMVHVLIKDATEAEDVVMEIHDRIGEMESSLENVLAQRDALRSIYNATIDVFQHLSSLASTRLPGYIAQAHDFTRVWHEENDRIAGGLDDLAHLNSFYDGFLDAYDGLIIEVARRRHVRQRVEKVLRDAKHKLDQLYEEDVNAREAFRVEKGDYLPSDIWPEVGREPMRIEFRRILGGKVKGAVSEQANDEEPTAGEREQRGGGQENHLSAVGDNTEVDEVIPELPRDLVEQVFARIQTRVKSTT

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
557 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.607 kDa
Sequence
MSAVDSSTSSGHPEREAQHETGLPPLETLISHLVAAKRSLSAINHVWRANEIVTSARSALEESVVVSARTGFLRSGLNNQLRLLYNVRAEVEEISLRGRSEFANALKSLDAADARLKKTLGLLRETIVHASFRPEGEEPKSLHDFVDERGVEELHSTLKSSIDRTNAAQADLDASNNAFDVELQSIKQALSTYRATTKLASSRGSVSSSGSQSGSSSSLPSISSMPSMVHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAAQSITGDMPAGVMGSHPGPGHGAGTGPTIEGDFNANPNAPLDPLSASEYREMVSVIVNDAAEAEDVVMEIQDRIGEMESVLETLTAQRDSFAAIYNATKEVFSYLSSLASTRLPGYIAQAHAFTAVWNDEHDRIKGGLADLSDLNALYDGFLDAYDGLIIEVARRRHVRHRVEKILRDARNKLDALYEEDVNARETFRVEQGDYLPSDIWPGLSREPMRVEFHRISGGPLKGVLQSPDQAQSPQPNEGEQLGHQDPQNPGDADSRFGEVIPDLPQELVEQALARLKSKRQR

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
Length
554 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.713 kDa
Sequence
MASSQSSSSSIRPQAGLNEGDHQSLPQLDTLISYLLGAKRSLSSITHVWRANEIVTASHSALEKSVVLCSRTGFLRRGLNGQLRLLYDVRSEVEQISYRGRDEFSIALKNLDAADARLKHTLDLLRGTIVHASFRPGDEEQKSLHDFVDERGVEELHASLKASIDRTNTARAELDTSNHEFDDELQAIKKSLRHYHTATKLASSRLSITSSSSSASDSGLLTLSSMPGQIQSLEAHAQEMATLLEALVRHFDLCVTAVKHTDGGGAVARSITGDMPAGVDGSNDGMPNIGAEINANLNAPLDPMTDAEYQEMVAVLIKDAPEADDVVMEIQDRINEMESIFEQVQAQRDALLSISKATIEVHSHLSSLASSRLPRYISQAHNFTRVWLEENDRINSGLVELSDLHSLYDGFLNAYDSLMLEVARRRHVRQRVEKVLRDTRHKLDQLHDEDAAARETFRAEQGDFLPSDIWPGVGLAPMQVQFTRLSGGQLDGGPIGQKPLEEPSGGEYAGAAKAGVSDGSAEGEQIPDLPRHLVEEAYARVKARNKVASQLHTV

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
551 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.95 kDa
Sequence
MSSSESSSVSGGGRPDAGRLPGEEQAMPRLDTLISHLVAAKRSLSSINHVWRANEIVTAARAALEECVVVSARTAFLRRGLNNQLRLLYSVRTEVEEISLRGRSEFAAVLKDLDDADTRLRRTLELLRETIVHPAFRPEGEDPKSLHDFVDERGVEELHAALKSSIDRTTAAQAQLDSSNHAFDDELLSIKEALGTYRTAAKLASSRSSSSASSSSTSNSSLPSISTMPSMLHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAAKSITGDMPVGVPVSGRMGSNIEEEINNNLNAPLDPLSNSEYQEMVNVLFKDAAEAEDVVMEIQDRIGEMESVLENVLAQRDALRSIYNATTDIYQHLSSLGSTRLPGYIAQAHNFTQVWHEENDRISGGLADLSDLNSLYNGFLDAYDGLIVEVARRKHVRQRVEKVLRDTRHKLDQLYEEDVTARETFRVEKGDYLPSDIWPEIGREPMRIEFRRISGAKVQAVNLQSPNEQEAITDEQKTANRLAPVESKDGDEIIPDLPRELVEQAFARLKARAKDAT

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
550 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.647 kDa
Sequence
MSSSESSSASGGGRPDAGQPPSEEQAMPRLDTLISHLVAAKRSLSSINHVWRANEIVTAARAALEECVVVSARTGFLRRGLNNQLRLLYSVRTEVEEISLRGRSEFAAVLKDLDDADTRLRRTLELLRETIVHPAFRPEGEDPKSLHDFVDERGVEELHAALKSSIDRTTAAQAQLDSSNHAFDDELLSIKEALGTYRTAAKLASSRSSSSASSSSASNSSLPSMSTMPSMLHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAAKSITGDMPVGVPVSGRMGSNIEDINDNLNAPLDPLSNSEYQEMVNVLFKDAAEAEDVVMEIQDRISEMESVLENVLAQRDALRSIYNATTDIYQHLSSLGSTRLPGYIAQAHNFTQVWHEENDRISGGLADLSDLNSLYDGFLDAYDGLIVEVARRKHVRQRVEKVLRDARHKLDQLYEEDVTARETFRVEKGDYLPSDIWPEIGREPMRIEFRRISGANVQAVNLQRPHEQEAITGEQEAANRLAPVESSDGDEIIPDLPRDLVEQAFARLKARVKGAT

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
550 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.484 kDa
Sequence
MSDSESSAISNNASDLNPSPGQENSMPQLETLISHLVAAKRSLSSINHVWRANEIVTAARSALEESVVVSARTGFLRRGLNNQLRLLYSVRTEVQEVSLRGRSEFATVLKSLDVADARLRKTLDLLRDTIVHASFRPEGEESKTLHDFVDERGVGELHTTLKRSIDRTNAAQADLESSNRAFDDELQSIKEALGNYRAATQLASSRTSASSSSPSTSNDSLPSLSSIPSMLHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAARSITGDVPATVHVNGRVGPNIEEGINANLNAPLDPLSNSEYQEMVSVLIKDAAEAEDVVMEIQDRIGEMETVLENVLAQRDSVLSVYNATTSVFKHLSTLASTRLSGYIAEAHSFTRVWHEEYEQIQSGLADLSDLNTLYDGFLEAYDGLILEVARRRQVRHRVEKVLRDAKQKLDQLYEEDVNARETFRVEQGDYLPSDIWPGIGREPMRIEFRRISGGNLKGIAAEPPDQDAAAAEPKQEARAVSSGDVGEDGEVIPELPKALVEEAIARFNARMRHLP

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Length
550 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
60.296 kDa
Sequence
MSASESSATSSVAPHDHGSSQVETSIPQLETLISHLVAAKRSLSSINHVWRANEIVTSARSALEESVVVSARTGFLRKGLNNQLRLLYSVRAEVEEVSVRGRSEFAGVLRSLDAADARLRKTLNLLRETIVHASFRPEGEEPKSLHDFVDERGVEELNSALKSAIDRTNAAQTELETSNCAFDDELQSIKEALGNYRAVTKMASSRTSASSSSSSASNASLPSMSGVPSMLHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAARSITGDMPAGMNVSGRGGPNIEEGINANLNAPLDPLSNSEYREMVNVLIKDAAEAEDVVMEIQDRIGEMESIYENILGQRDAVLAVYNATTSVFEHISSLASARLAGYIAQAHTFTRVWNDEHEHIQGGLSDLSDLNTLYDGFLEAYDGLILEVARRRHVRQRVEKVLRDAKHKLDQLYEEDVNARETFRVEQGDYLPSDIWPGIGREPMRIEFRRISGGTLKGVQDQHPDEDTAPPSDPKDVANHTTDENRDEGETIPALPKALVEEALARLKARNRQAT

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Length
546 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
59.779 kDa
Sequence
MSASASLSAGSDASGPGSPAGDQGNALPQLDSLISHLVAAKRSLSSINHVWRANEIVTSARSALEESVVISARTGFLRRGLNNQLRLLYSVRSEVEEVSLRGRSEFASVLKSLDTADARLRKTLDSLRDTIVHASFRPEGEEPRSLHDFVDERGVEELRAALKSSIDRTNEAQAELDTSNSAFDDELQSIKQALGNYREATKLASSSSSSSSASNSSLPSLSSMPPMLQSLEMHAQEMANLLESLVQHFDLCVTAVKHTEGGGAAARSITGDMPAAVTVSGRGVPNIEQGIHDNLNAPLDPLSESDYQEMVNVLIKDAAEAEDVVMEIQDRIGDMESILENILSQRDVLLSIYNATIGVFRHLSSLATARLPGYIAQAHSFTRVWGEEHDRINGGLADLSDLNTLYDGFLEAYDGLILEVARRRHVRQRVEKVLRETKHKLDQLYEEDVNARETFRVEQGDYLPSDIWPGIGREPMRIEFRRISGGILKGAPPEQPDAQDQPAAEPNEPQSGPSETTEEGEIIPHLPKSLVEEALHRLKARNRQAM

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
519 amino acids
Function
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation (By similarity). Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity (By similarity). Plays particularly a role in pexophagy and nucleophagy (By similarity). With ATG13, is required for ATG1 activation by autophosphorylation (By similarity). Recruits ATG9 to the pre-autophagosomal structure (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236). Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
Similarity
Belongs to the ATG17 family.
Mass
58.016 kDa
Sequence
MASSSATSLRQGSSGASSGHSHPQSTSLSRHSNSNSNSSRSRSFTHQDVDPNAPSISIDTLVNHLLVAKRSLSSMTLVLRANEIANAARQSHEDVAILAAQAGFLKESILDQTTILVRVRRSLQGTYDWGKRDFKKLIRSMDLVDGGLEQTMEMLRDTSVEGVFRPEGEERRSLLDFIDEGGVHGVREAMKKSIQELQSFDGDLLRFDTDIRNLRKIITDTPALTHDDTHFPTFELLEGLVDHSANMAQLLVSLTHHFDMCVTAIRTTEGGVALARRRAAEVTQTQGNDGVSISGVIAEQESNVSDLEPNTAKDRAEMLKVVVQDAGEVNDVVQEIQERLTAMEQDYLVLQEQHDISKQAYSNMLEAYAVLGEIGDRLADYLAAEGDFKSRWDMEKESVFSKLQEMQQLKEFYERYASAYDSLIIEVERRRAVDDKVKNIWRKAQDSVDKLLDADRASRETFRQDVGEYLPTDLWAGMQGSAKKWTVVPDGEGEDVKGPALRRSVVEGARERLGRVERR

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
504 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
55.292 kDa
Sequence
MPSSSSARSSQSLRSSAAAAVSTSSGAADQPSVPIEILVEHLLAAKRSLSSMTLVLEANDLTTQARSVHEDSVVLAARTAFLRAGIAQQIHTLERIRRGLARTYDVGRRDFEQLIKVLDDAGERLTRTMNVLHNTIVDPVFRPAGEEPRSLMFFVDEGNVDRLTKSLKESIAELKAAETSYDGDLLRFDNDIRSVKKHLLAAPGLPSPSNSVFSRPMADLVRTLTNHSHAMAENLSSLTRHFDLCVTAVRASEGGAALALRKAAEDGPSTISISGVIRGDGTDADDQDIKTMSARERDEMLRVVMQDATEVGEVVRDINSGLEEMQALGALVEQQAAHVRTAHECTLDAFRRLEEVEARLGSYVAAEREYVDRCEVEKDAIHERLAQAEDLVVFYEGYAGAYDGLVLEYERRRNVEDKIRALWRKAAAAVEKLEEQDAAARDSMRKDVGDYIPGDLWVGMDDPVRKWKVVAVDEGEGGSGEIEGSSVRLKKGTVEAARERVHGR

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Botryotinia fuckeliana (strain B05.10)
Length
500 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
56.338 kDa
Sequence
MASSPNAPGSHSHTSISTVNPPPPAHTNQGLEIPLETLVSHLLASKRSLSSISTVWRANEIVTSAKNALEESAILQAKTRFLQSGINEQMKTLLKVRKTVEFVYNDGQEDFSNVLHNLDAADARLESTMNMLRSTMVDAAFRPAGEEPRNLLDFVDEQGVEKMRDGLKELIDESKEAEAAFGTSILSFDSDIRSLKSGFKNSKRKTSSYSPIPNHLYTLEGHAQEMASLLSSLSSHFDLCLNAIRHTEGGYAAVRNAASNPPPGAEPVSVSGVMSNSHDDINEAPLTEHEREEMFSILEKDAAEVEDVVMELHDRQNEMEAKHDAILDHVSHLAEQFRHTASVYKTLEGVYQRLPRYILAGHDFRARWEDTKVHINEQMNELEGMRLFYENYLSSYDGLILEVHRRTVAEEKARSIAKKAMEQINKIYDIDVKERNDFKFDVGDYLPVDLYPGISEAPPKWDFRLVEDEEGGSSTPLLERSVVKESFKRDRERHRNSKDN

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
Length
492 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
55.103 kDa
Sequence
MASPTNAPGSQSQTSVSSANHPDPIIHGREILETLVSHLLASKRSLSSISTVWRANEIVTSAKTALEESVILNARTGFLQSGINEQMKVLMKVRNSIECVYNDGQKDFKNVLHTLDAANARLESTMDVLRSTMVDAAFRPAGEEPRSLLDFVDEQGVEGMRDGLKELIRESKETQKEFDTSLLSFDDDLRSLRSGFKNTKVSPPSYSPIPSHLATLEGHAQEMAALLSSLSSHFDLCLNAIRHTEGGYAAVRNAASNPPPGAEPVSVSGVMNTSHDDINEEPLTEHEREEMLFVLEKDAAEVEDVVMELRDRQNEMEIKHDAILDHVSHLTEQFKQTTSIYKILEGVYERLPGYIIAGQDFRARWEDTKAQICGQMDDLEGMRLFYENYLSSYDGLILEVRRRKVAEEKAKTIAKKAMEQISKIYDADMKERHDFKHDVGDYLPVDLYPGINAAAPRWEFRLMEDEEAVNSSPSLERELVEVSSKRDGEAQG

Gene
atg17
Protein
Probable autophagy-related protein 17
Organism
Dictyostelium discoideum
Length
488 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
57.014 kDa
Sequence
MDFSSKSLELCKSHSNQTDQLLKISKQTYEKYDNSLSKLHLIIRELNKQLIILKETSTQFNDRYNTFINDFTSLSNQKQSLFTSIENKLEILKKKYLDKGLVFKNNNNNNNNNNNNNNNNNNNSNKSTEDDNNENNNNNDVNKNNNNNNNNNLNTLYDFIDIESLELIKNQFLSELSGLNEICDKSKQIYKSTNESNLEMENRFLEIQKQYNKQIEESNSLSDLLTQQNNLYKTIQNQLINVASQCDFITFYKPSPSPLSPSPSPSSSSSSSSPSPSSPQQQHDFNINNKKEQIQLLLTSSLENIQLMSKNVKDIENQFKESCSIYTLVYLLNEKLSFGNDFSENWETFERFNCIFEQRLAGANYFIGELYSLGKWYDLFDESYDNLLEEVKRRQKEYLRQKTIAEQFNEELKHNYNQEIQNRLKFYDSYGKYLPVSLFSTISDQPISFQVKQIIEESVIDYSFNPLNLKRSSPINQQQQQQQPPPNS

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
487 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
56.482 kDa
Sequence
MSSGVDRDTVISWSEQAQTTLQEAKKMCTRAQASLQSTTYQLVTQLPERLQFVTFMVDALKQQHELLTSIVESQSRIRKESVSQFNVQVERDLTPALAELDDILARLAKAKVPSYLINNVVHELEVHIDTLVEDRNLCDFISMDDIKLLTTNIEIYKANCTKLHGLLEKTMNESVIEPYQIIALKKYHNIMKQYKELMPVQLGMNLAPDVSPYKLNNLINTILKENSSLEHELVPMLEMMTNHYDQCVQGTLFFNTKNPKDPSGDVNFEVLRNDALELPDVLKELNTVYDIIVNNEVRTKKLLSSEFSRIDSLISMIKDLLEFYTDYKATHLSKYMILVLSCDEIFGKCSIAMNSNQTPLEAYIETITSLSYHYTQFLSIYKSEYLTELFYEQYTYPRKYLAKLTDFLNNDMFHLQQEEYERRKNWLARYGEFIPNEFKLPGELNQPSIIQVVTEGLDDVQKDYNDGKFNESAEEINLSDLIKTMKL

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
483 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
55.71 kDa
Sequence
MHATVDRATVTAWAKQAQSTLEKAQTLCTNAQTSLHATSYQLTSHLPDLLEEANVLYESLKTQHELLAKISESLRRSIRDQLLNTLEKQQSTLLQPALNNLDDIVGHLSATIVPSFLIEKDEAENRTLADFISTDSINLLRRNIQIYTNNHEKIRQLLNNKLQDVILSPFHEIGSKKFNKTVKLYEEITPLQLKLKAITSNIAPLDSSNVVATLLKENAALENELVSILEMLTNHYDQCTQGVQILYSGGSQQVNLEILKNDAQELPDVLKELHTVYDIIVNNEARAQKFINAHSPSIEVVIATMKDQLSFYRSFKSKNIPEIMVLFTVCEEILMKSPIEDPGGPEQTPIEKFTDTVNQLVYHYTQFLNVFKSQYLRELHHEQFSYPRKFLSKLTNFLNDELYKMQIEEKERRRAWLTKYGDFIPKEFRLPGEYNQPVITQVVTEGLEDVQKEGADAERHITQEKELLELLRKMEELNRERRY

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
476 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
55.407 kDa
Sequence
MTNEINSATVTQDEVIKWSREAQSTLEKTQKICTDAQSSMQKTAQELTILIPDKLQAIEFLFKSYREQYDSILKQIETTKIYLHTNIDKVFNDIKDLLDPSLARLNNILLELKKTRVPSIVVEGTSEGKTLFDFTSIQSINLLKENIGIFKSNCSKIKNLLDLEVKEKLNIEQDRMNSRWNKSVKMYDLIAPLQLELRALIHGASNESNSFMGTILRENQALENELVSILEMQTNHFDQCMKAVELISSGNGCDMNLGVLKNDAQELPEVFKELTTIYDIILRNEERSKKFLATHMPNIEKISDIVKEELAVFRKFKTEEIPRYTFLIAECENKLKECSMPVKSDQSPSQVYTQTLQELTEHYVKFINIYKTKYLAELHHQQFTYPRKFLKKLTEFLNEDIYRIQIEESERRRQWTSRYGEFIPSEFKLPGEHELPVIVQIITEGLEYIQKEDGQEEEPNIGNEKELMDMITGSNK

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Pichia angusta
Length
429 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
49.398 kDa
Sequence
MAIPIAQWVADARANLAHAEQVCNDANMYLTSTSEKLRRREMKVPKLIYYLDALKQQLRLLEIIRDSLVLNLNGVMEKRAALQSQLLKDVDRLHQTIDTLKNTVVVFDGQTTLYEYISESGVEELFNGVSQNLKDIQTLIKGNRTDALLIRLTSDLDHLSNELNALDSKFRDMRLVDTQSSSIDPISKLLEINAELEHDMVAILTSFNNHYDQCEKGEAILKDPAVPQDEKDELVSVLQNDVEELPEAQRSLTSNAEIIKKNCKEVMKILDIFEDYFQRVETYVCELQEYGESKLRVQLKEFSDINTEVSRKLEIAQTHQDELVQYNSDFQQFVRSYYSLILELDRRMRVNEHISSAIDNFRSTISNIVEKDHEKRMEFLQKHGDFIPQNLVDSSVINSGTPQISINFDQEPLPAISKEVVQLAKKMQK

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
423 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
49.864 kDa
Sequence
MSDAATTIPSDEIDKLWNKARNQLVEAQVECEESLKILSKVRTEMDSSQKSRFKLKFILNCLVNQVEFFKNIMLEKCISTELIDNEWSKLVLVEIVNDVSYWQNEITTKMKILQGTKYDLTDDHSSLSDFICMDHVDILQQKIDEIPIIKQQVTNIRQHYKSIKDRIENQLVAVKLKKLRTYFDSHFSRDSKNNLFKLLESDYVTELNEFENELADFLRSITDHFDKCTILKEQQIPLPDLKELFQIVKKDDTQLENIRELVFETGLEVKAFSKKVNETISEIMDKIGGFHLLASKIVTELEKCEEYLSIFQKIANLVFVYKESCIKKIEQVQQLCEFYDKFKLGYKNLLRERDRRKATALQMEKILKECQEKLQALSDADLDQRQQFLLENGDYLPENIWPGYIDDMESMYSFEYSIHNVPN

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
Length
421 amino acids
Function
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation (PubMed:26442587). Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity (By similarity). Plays particularly a role in pexophagy and nucleophagy (By similarity). With ATG13, is required for ATG1 activation by autophosphorylation (By similarity). Recruits ATG9 to the pre-autophagosomal structure (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
49.638 kDa
Sequence
MSYHYDGIPDIEIDLYWNKARNHLLKAQVECEESLKLLSTIRSEMDSCQKSRLKLQFILNCLVNQVEFFSSVILEKCIAVELLDNEWSKVVLVGVVKDLNYWQDEITNKINALKNTKYDLNAEYKSLADFICEDHVEILQQKLDEVPFIKKQVSNIRQHYKSIKEGVQYQLKAGKVKKLKKYYETHFSRDNHLFELLEGEYLTKLNSYESELTDYIRSITDHFDKCSILKADGLPPQDLKDLFEVVKNDDAELEHIRELIYESDAEITQFYKNVEGTITSIKENVADFYGLSTKIMVELEKCEEYVSIFQDIAKLVSVYKESCIRKIEQVQELCEVYDKFKKAYFNLLKERERRKSVAIQMKSILDECKGKLMALNEDDLDHRQQFLHENGDYLPENIWPGKIDDMTPLYSLEYTIYNEQK

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
417 amino acids
Function
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity. Plays particularly a role in pexophagy and nucleophagy. With ATG13, is required for ATG1 activation by autophosphorylation of 'Thr-226'. Recruits ATG9 to the pre-autophagosomal structure. Plays also a role in regulation of filamentous growth (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
48.639 kDa
Sequence
MNEADVTKFVNNARKTLTDAQLLCSSANLRIVDIKKKLSSWQLSISKLNFLIVGLRQQGKFLYTILKEGIGTKLIQKQWNQAVLVVLVDEMKYWQYEITSKVQRLDGIVNELSISEKDDTDPSKLGDYISRDNVNLLNDKLKEVPVIERQIENIKLQYENMVRKVNKELIDTKLTDVTQKFQSKFGIDNLMETNVAEQFSRELTDLEKDLAEIMNSLTQHFDKTLLLQDKKIDNDEREELFKVVQGDDKELFNIFKTLHEVIDDVNKTILNLGQFLQAKIKEKTELHSEVSEIINDFNRNLEYLLIFKDISNLIDSFKNSCTQDIQTTKELCEFYDNFEESYGNLVLEAKRRKDVANRMKTILKDCEKQLQNLDAQDQEERQNFIAENGTYLPETIWPGKIDDFSSLYTLNYNVKNP

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
417 amino acids
Function
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity. Plays particularly a role in pexophagy and nucleophagy. With ATG13, is required for ATG1 activation by autophosphorylation of 'Thr-226'. Recruits ATG9 to the pre-autophagosomal structure. Plays also a role in regulation of filamentous growth.
Similarity
Belongs to the ATG17 family.
Mass
48.656 kDa
Sequence
MNEADVTKFVNNARKTLTDAQLLCSSANLRIVDIKKKLSSWQLSISKLNFLIVGLRQQGKFLYTILKEGIGTKLIQKQWNQAVLVVLVDEMKYWQYEITSKVQRLDGIVNELSISEKDDTDPSKLGDYISRDNVNLLNDKLKEVPVIERQIENIKLQYENMVRKVNKELIDTKLTDVTQKFQSKFGIDNLMETNVAEQFSRELTDLEKDLAEIMNSLTQHFDKTLLLQDKKIDNDEREELFKVVQGDDKELYNIFKTLHEVIDDVDKTILNLGQFLQAKIKEKTELHSEVSEIINDFNRNLEYLLIFKDISNLIDSFKNSCTQDIQTTKELCEFYDNFEESYGNLVLEAKRRKDVANRMKTILKDCEKQLQNLDAQDQEERQNFIAENGTYLPETIWPGKIDDFSSLYTLNYNVKNP

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
Length
413 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
48.447 kDa
Sequence
MKIERFVNASRKTLVEAQVLCQDANSRISNARSSFSHWERSISKIRFLLNCLKNQGSFIKNCILKVGIEENLIEKEWTQSILVDLAKELKYWNSKINEQVRVLDSIENILDEDTKSESKNLGYFVSRDNLDILEKRLKEIPNVKYHIDNIRGQYNTMFKKVSNYLINKRLKSVQEYFLTNFENDSDDIKKLTTTLPSKLVSLEHDLADYLSSITNHYDQSKLLQTLKPADPDYTDLLEVVKNDNSELDGIVTLLRETVDEVDETLKTFLGIFNEIELKQKECNKLLFGVIEEFKINHEYLLIFNDISSLIDNFKETCIEDINNTRSLCIFYQKFEIGYQNLLFEIERRKTVAQKMTDIIKNCELELSKINEEDQKNRSEFLKLNGDYLPENIWPGKIDDFSPLYSLEYSIKEI

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
413 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
47.998 kDa
Sequence
MSSSNQVKGFYFNAQRRLSRAQALCQNSQDTLHNMQLLLVRWQRTVSKLQFTIHCICNQTVFLAECILKKTVGQQLIETEWKRMLLDELQGEMQRSQEEITGKIDALRRTKNELDGSGATLADFISMENIFLLGDKLKDVPVVQEQVEHIKVQYESLVDKVVEQLQNNRVRKLEADFAAAFRSGKNDFNAFSMKYLQKIRQLETDLADILKSLTDHYDKCSLLKAGDLPAAEQAELFEVVKNDDQELDSIMGVLEVIVRDIKSLAKNVSIRLRQKERDKQQLKNAMGKAHSELLKYEEHLTVFQGIDDLIRNFKASCLHNVSKVRELCEFYDNFLNSYQVLLREVERRRRVAKQMEDILQACEGQLMALSDTDLKQRQQFLMRHGDYLPENIWPGNIDDLSPLYDLEYRIKKV

Gene
atg17
Protein
Autophagy-related protein 17
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
411 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
47.062 kDa
Sequence
MELLQQWTQQAKAALTQARQLCGDAHKFNEDAKTDLRNSIKQHQQLKELAKLTASQCTRLDSSTALIKQLLDLVQNYPTFNQLNVLHDRLESSLKRLRDCTLDPALGSEYTNLYAFVDDTALEDLKTRLRGVTDGVWNAFEKLAGLLEEDLCANYHKRLEAVSLDFLPPAYNDTAEELADLLLQVAQHYDQCSEALNIYDTLSDAEKKDLQEVLQSDSNHVPSVLTELRSGLDQTIHYFNAVQSYKSKVDSATSILEALAEELNKNQLTNQRHEAAHELMRAQTGLEIPQLAQELVQLERHYTHFAKAYTALLQEIHRRQTYENCVRSIVDEFVGRLEKEQQAEAKCRIDFFNQYGDYLPQTLWGAVTDPPLHFEIIEHQYTELPNVKVIPDKNDKKSKQREKSSTTASKR

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
409 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
47.978 kDa
Sequence
MPESLAERARSTLLKAQVLCREVESRIAEVKDRLSQWEKNRHTLRFLVSCLEHQLGFLEQCALRQGIGRALIETEWSQVVLVDLVNEMKLWYDKIQLRLERLDQVENILVADNKHLSHYISQEQALVLKKRLDEVPIIRPQIENIQTQYDTMCKRVRQKLINKRLTEIKTIFDSQFGDELTETAELTEVKPRDLDSIELELVDYINSLTDHFDKCQALEKGLFNDSNEYDELLKIVSADDSQLDDIMKHLLNTIDSTNHQIDKVYEILDIKTKQKTILHGKINELIANCTKYSEYLAIFKGIATSIEKFKEGCMQDIQLTKELYKFYDEFENSYNKLLQEVQRRRALSQKMLGIIKNCENELKTLHDEDQKLRTHFLSENGAFLPETIWPGEIDDLSPLYALDYHIKEI

Gene
ATG17
Protein
Autophagy-related protein 17
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
408 amino acids
Function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Similarity
Belongs to the ATG17 family.
Mass
46.433 kDa
Sequence
MEQLFREAQDALAAAGPLCQESQDVLARARQNLEVAVHLGIRTQFLAKAHAHQWTLASKFYSNALTRTKKSLETVTRQQTRFQAARGALEEALGELAATPVQLRVNNGAHNLREFVDEDLISAQVQGKGWNEVHEEALNVFRVLLPEIQRHGDIVNRSKKEFEREKAEQTELLIHQTSDSGIYDLLNSAEACSEDMANLLQSLARHYDLCERGQDLSTGAIEAEDVNELGELRAVLENDAQQLPDVLDELQERLDEVKQGCQGVHNHMTQMYHSYSLEVRQLEGIQAVEKTMDATLEICETQQRDTKEYLLKVQRYVSETSAVVTHYQTFLNSYKALLHEAERRNAAEAKMKDYVTEVNAKLAQMSIQETNRRQDFVAQQGDYLPADIWDELLLPSRRFEARELDGEL