Protein
Mitochondrial glycine transporter
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Function
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Sequence
MSNNAAYLAPQVKTTSTSSKTTFHFAAGLCSGLTSSILLQPADLLKTRVQQSQQTAALLPTLKTILSSPHPIRSLWRGTLPSALRTGFGSALYFTTLNALRQPLAQSAVLTGSNGSANKGTKSSSALPKLSNWANLGTGAVARVAAGFVMMPVTVIKVRYESDYYAYRSLYGAGRDIVRTEGFRGLFSGFGATAARDAPYAGLYVLFYEQLKRHLAGLKHSGTADQPLAATSSSSINFISGGLAAGLATTITNPFDAVKTRLQLMPGKYGNMMRAVKLMIQEDGVRSLFGGLGLRITRKALSSALAWTVYEELILRAEIRWAEKAHAHV