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ARP4

Gene
ARP4
Protein
Actin-related protein 4
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
534 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
56.97 kDa
Sequence
MPGVYGGDEINALVIDAGHSSSRVGWAGEDAPRVVLPSYYGHTSITDDAIAELESQAAFATSSSSTVEPTERAEPVDGDETMADGQALSTSNGNGGAAATQEASDHRLRQARAKSASKTLRFSVDREKKRRRFVGDNELNLYRTNLEIAPIFDDDGMLADASAFAQLCSFGLDSLSCDASEHPLLLTEPAWNSRESREKLTELAFETLGSPAFYLANRSVLSSFAAGKPSSLVIDVGSTNVSTIPIVDGFILRKGIYRHNNGGEAINRALLYSLHHGRGATFAGVTPQYVIKSRSSVDPGTPANVVLRQERVQGASSSFRSYHINRVVNDFKESVAQVLEVPWDDQQAQFRSGRMYEFPDGYNDAFGVERLRAAEVLFTPALWNGVSSSESFGAVLHASSQPSSEAGAVNGGSVSAAGATSVAGGKAAIGLADMVLSSINAVDVDSRPSLYGNIVLVGGSSLIQGLSDRLSYELGVKAPNQKIKIHSPGNTTERRHSSWLGASILASLGTFHQLWISKQEYEEHGAAIVHARCK

Gene
ARP4
Protein
Actin-related protein 4
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
520 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
57.976 kDa
Sequence
MSNPALQVYGGDEINAIVIDPGSFVTNIGYSGTDCPQSIMPSSYGNVETDGDTKRIFNEQPLLFPRAGMEIKPIVENSTIVDWDRAQEQWEYALNTDLKFESNKGTPVLLTEPIWNSEASRKKSLEILLESMEFEACYLAANSSAVSFAMGRPTCLVVDIGHDVSTVSPVIDGMTLSKSSTRNYVAGKYLNHLIAKNLKPREIVPIFQVLKKKPDFVKRTLSFDVNESVINFANERQFFQEFKETLLHIAPKSLSSFKDELATQTKRSLEAPWGEELIFDADTRYSFAEQLFRPVKEDFPEGWPASTDGIVKTWHNDYVPLKRTKPGTSTNTKEKENTAESTPVPASTEQEAVDSPSQEPNENGKRPVENKEDSSNNEQNSNEIKNEDANSNESSAKATVPSNGIQAKGEDEVAGIVDLINKSMMEADVDLRATLAHNVVLTGGTSKIPGLSDRIMHELNKSLPALKFRMLSSGHLRERQYQGWLGGSILASLGTFHQLWVGREEYEEVGPERLLKDRFR

Gene
ARP4
Protein
Actin-related protein 4
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
493 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
55.187 kDa
Sequence
MSNSALQVYGGDEITAVIIDPGSYTTNIGYAGTDCPQSILPSSFGEIHEAEESTSEDNTEKTRKTRKVFSEQSIPIPRPDYEVKRVVENGQVCDWDSAVEQWSWALRNELHIESNRGIPAMLTEPLWNSKENRSKSLEILLEGMEFEACYLTATSTAVSFATGRPNSLIVDIGHDIASVTPVIDGMSLSKSTRCNHFAGRFLNKLLTDYLKPREIIPLFEVEQRKPEFKRRSFSYSVADSLYDYANSRGFFQECKETIFQVATTPIAQEKNNQATSTGRTIESPWNEVIEFESNDRYQFAEQLINPLKESVPDDWPVNVAGVVETWRNDYVPMKRNKVGSGNNKEKEGTKESTPLDSNTATPLPESSSTTNENGKRTAEDIKREELPGIVDLISSSISSCDVDIRASLAHNLVITGGSSTIPGLSDRILNELNMKFPALKFRVLATGQSIERQYQSWLGGSILSSLGTFHQLWIGKKEYEEVGSERLLHDRLR

Gene
ARP4
Protein
Actin-related protein 4
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
492 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
55.665 kDa
Sequence
MSSSGNNASVYGGDEINAIVLDSSSFHTRIGYAGDDFPKIITPSSYASPNEDAMELDNKKKNGKSKSSKIFGESINIPRSNHNVSPILKDSVIIDWEAAIEQYHYYFDDVLTLNYKEQPILITEPVWCTPQYRQTLLETFYENFDFPALFLAKSPTCISFQQGRPNCLVVDIGHDSVSVTPVIDGISLLKNSMKTNYGGQYLNDQIEDMLTHKFSGVNFENRYRIKSKTPTVYPEESKYTVRDLSENITQSFDDYQRQNIWHEFKETMLEVPEKKFNTSNTSQANSLKEIYSQDSNKRLFELPTGQSLELCLERFQLADSLFDPQSYKFNNPDLATKYPPSNGELSLTNSYDDYKPLKRARKAESNQSTPPPSDAKKPSSKTSQIRGLTHLITHTLSTIDIDLRSSVAHNIIVTGGVSLIPQLTERLYSELSNSNPGLKIRLHAVGNSSERFNQAWIGGSVLASLGTFHQMWVSKQEYEEAGAERILNQRFR

Gene
ARP4
Protein
Actin-related protein 4
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
489 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. ARP4 recognizes H2AS128ph (gamma-H2A) and is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to gamma-H2A as a response to DNA damage.
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
54.832 kDa
Sequence
MSNAALQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQSIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPKEIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQLWVGKKEYEEVGVERLLNDRFR

Gene
ARP4
Protein
Actin-related protein 4
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
479 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
53.866 kDa
Sequence
MSNSALQVYGGDEITAVVIDPGSFTTNIGYSGTDCPQAILPSCYGKYTEGEKDELFSEQSIGLPRKDYEIHNIVQNGEVVDWEKAEKQWDWAIRSELRFETNSGMPALLTEPIWNSEENRKKSLEVLLESMDFSACYLVPTATAVSFAMGRPTCLVVDIGHDVTSVCPVVDGMTLSKSSMRSYIAGSLLNELIRSQLAPRKVIPLFQVAQRRPVFMERKFDYEIHPSLQKFVNERQFFQEFKETMLQVAPTSISKFKSEIETTSKRSIEAPWGEELVYDSLQRLEFAEQLFTPDLSQFPEDWPISKDGVVETWHNDYVPLKRNKPGTNVKDKEGTLDATPVPDENSVTSADQPNDNGKRNLEETTPDQKNEVSGLADLIYSSIMSTDVDLRTTLSHNVVITGGTSSLPGLMDRISAELNRSLPALKFRMLTSGQLRERQYQGWLGGSILASLGTFHQLWVGKQEYAEVGADRLLKDRFR

Gene
arp4
Protein
Actin-related protein 4
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
472 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
51.437 kDa
Sequence
MNASVPPSAAEYGGDEVSAIVLDPGFSTTRAGFAGEDTPKSLVPTYYGKYSFEGQEKLIFGDDVFVTPRPSLSVGNPMGRDGVVEDWDMAEKLWEYSFTSRLTGAKPSNPLHNGLNDLVEGELPTEMEGVETNEKPLADSPLLMSECSWNPTKAREKTIEIAMEKWGTPAFYLARNGVLASFAAGKASALVVDIGASNISVTPVHDGMVLKRGVQHSPLGGDYISSQIRALFKTNTPQPITITPHYLISSKTAVEAGQPPQAKYKTFPPEKAPDASYRSLLEERTLTEFKECVVQVWPGPTKLSAPGPNGVPNEEMARSTPGRPFEFPDGYNQVFGVDRYRVVESLFDAKATILDPDSQFPAPTPAQTIPELIKAALNGVDVDLRPHLLANVVVTGASSLLYGFTDRLNQELMQLYPGPRVRISAPGNTSERRFSSWIGGSILASLGTFHQMWISKKEFDEHGPNIVEKRCK

Gene
ARP4
Protein
Actin-related protein 4
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
471 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
52.433 kDa
Sequence
MAQQPLSSSAQPTDIYGGDEVSALVLDPGYCSTRAGFAGEDVPKSILPSFYGHVTGDNSRDLFGDECLIPRENYEVRNYMNKDSVVEDWDVAARIWENMLVNRLQPERQTPPSKNGLNDDPRPEGQDGEGDVAMDDAEAESMEKPLGENPLLVTEAPWNTPKAREKAIEIIMENWGCPAFWMSRTPVLAAFAAGKATSLVIDVGGANTSVTAIHDGMVLKRSIQKSPVGGIWLSSQIRSLFETSEPQVELTPTFMIENKTPVDALSSPSVRLRNFPYSITDSFRAYEEERVLTEFKESVVEVWRGPGRYSVPGNEEFVKTQPGRVFEMPDGYNQMWREQRFRVTEGMWDENAGYPIPEADRLNKTQTIPELIRAALNAVDVDLRGNLLANVVVTGSTSLINGFNDRLNTELMAMYPGLKIKIHAAGLTSERRFGAWIGGSILASLGTFHQMWISRKEYEENGPNVVEKRCK

Gene
ARP4
Protein
Actin-related protein 4
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
468 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
52.658 kDa
Sequence
MATASTTTVYGGDEINAIVLDPGSYTTRIGYAGDDFPKVITSSYYGQVKNDKKKIFGESINVPRANYDIKPILKESIIVDWDAAIEQYQYYFDQQLKVVGPEQPILITEPIWTETSYRQQLVETFFENFEFSGIYLAKSPTCVSFQQGRSNCLVVDLGHDSVSVTPVIDGICLLKSSMKTNYGGKFLSNEIQDYLIDTKKVVMEPSFKIKSKIPTTYPDPPKYELKNNNTIPTSSSSSLSQSFLEFQNEKIYHNFKEILEVPEKNSSSGTTTTTTTTNKDSSRLFELPTGQSIVIDRFKIAESIFDPTIYKFTNSKLSFPPNNGEISITQANEYRPLKRVRKNDDEEEDSNQSTPKPEVNIRGISQLISHTLSNIDIDLRASLANNIIVTGGVSLISQLTERLYLELSNNNPGLKIRLHAVGNSTERINQAWIGGSVLASLGTFHQMWVTKEEYNEVGVDRILNQRFR

Gene
arp4
Protein
Actin-related protein 4
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
466 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
50.692 kDa
Sequence
MLIAICVQDEISAIVLDPGFSTTRAGFAGEDTPKSVIPTYYGKYTYEAQEKLIFGDDIFVTPRPGLSIHNPMGRDGVVEDWDMAEKVWEYSFTSRLTGPKAGNPFQNGLNDVANGELPSEMEGVETEEKPLADSPLLMTECGWNPTKAREKTVEIAMEKWGTPAFYLARNGVLAAFAAGKASALVVDVGASNISVTPVHDGMILKRGVQHSPLGGDYISSQLRALFKTNSPQPITITPHYLVASKTAVDAGQPAQAKYKTFPPDKAPDASYRTLMEERTLSEFKECVVQVWPGPNKLSATGPNGVSNEEVAKSSPGRPFEFPDGYNQVFGIDRYRVVESLFDAKAAIPDPESVFPAPTQAQTVPELIKAALNGVDVDVRPHLLANVVVTGASSLLYGFTDRLNQELMQSYPGPRVRISASGNTAERKFGSWVGGSILASLGTFHQMWISKKEYDEHGPNIVEKRCK

Gene
ARP4
Protein
Actin-related protein 4
Organism
Oryza sativa subsp. indica
Length
443 amino acids
Function
Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure.
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
48.494 kDa
Sequence
MYGGDEVSAIVIDVGSYSCKAGYAGDDTPKAVFPSVVGSIEQTGETDEAKADKEAEAASDSKNGAKPMDVDKAKTKRKLYVGQELEFRRDHMEVISPMKDGTVTDWDIVDNIWNHAFRQRLLINPEEHPMLIAEPSTNTGQQREKAAELMFEKYKVPALFLAKNAVLTSFASGRATSLVVDSGGGSTVVAAVHDGYVLQKSVATSPIGGEFLTDCMMKSLESKGVVIRPRYSFKKKEVGPGEYKVVDLDLPNTTESYKLYCMRAIASDIKESVCRVPDTAFDEVAYANVPTTSYELPDGQTIEVGADRFKIPDILFNPSLSQTIPGVDGFADSMSVRGLPRMVIDSVNRCDVDIRKELLSSILLSGGSSSILQLKERLEKEVLEESSGNTRVKVLASGNSVERRFSVWIGGSILASLGSFQQMWFSKAEYEEHGVSYIQRKCP

Gene
ARP4
Protein
Actin-related protein 4
Organism
Oryza sativa subsp. japonica
Length
443 amino acids
Function
Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure.
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
48.494 kDa
Sequence
MYGGDEVSAIVIDVGSYSCKAGYAGDDTPKAVFPSVVGSIEQTGETDEAKADKEAEAASDSKNGAKPMDVDKAKTKRKLYVGQELEFRRDHMEVISPMKDGTVTDWDIVDNIWNHAFRQRLLINPEEHPMLIAEPSTNTGQQREKAAELMFEKYKVPALFLAKNAVLTSFASGRATSLVVDSGGGSTVVAAVHDGYVLQKSVATSPIGGEFLTDCMMKSLESKGVVIRPRYSFKKKEVGPGEYKVVDLDLPNTTESYKLYCMRAIASDIKESVCRVPDTAFDEVAYANVPTTSYELPDGQTIEVGADRFKIPDILFNPSLSQTIPGVDGFADSMSVRGLPRMVIDSVNRCDVDIRKELLSSILLSGGSSSILQLKERLEKEVLEESSGNTRVKVLASGNSVERRFSVWIGGSILASLGSFQQMWFSKAEYEEHGVSYIQRKCP

Gene
ARP4
Protein
Actin-related protein 4
Organism
Arabidopsis thaliana
Length
441 amino acids
Function
Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure.
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
48.937 kDa
Sequence
MYGGDEVSAIVVDLGSHTCKAGYAGEDAPKAVFPSVIGAVDGVEAMDVDVDSTKTNSNSEDSKTESEKEKSKRKLYVGSQAMSYRRDHMEVLSPIKDGIVSDWDLVDNIWEHAFKSCLMIDPTEHPMLLAEPPLNTQQQREKAAELMFEKYKVPALFMAKNPVLTSFATGRATSLVVDCGGGSTTISPVHDGYVLQKAVVSSPLGGEFLTDCLLKSLESKGIKIRPRYSFKRKEVRAGEFQVEDVDIPDTTESYKLFCQRMIVGDIKDSICRVPDTPYDDKSYSNIPTTSYELPDGQTLEIGADRFKVPDVMFNPSIVQTIPGMEKYAEMIPSVRGLPHMVMESINKCDVDIRRELYSSILLAGGTSSMQQLKERLEKDLIEESPHSARVKVLASGNTTERRFSVWIGGSILASLGSFQQMWFSKSEYEEHGASYIQRKCP

Gene
ARP4
Protein
Actin-related protein 4
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
432 amino acids
Function
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Similarity
Belongs to the actin family. ARP4 subfamily.
Mass
47.043 kDa
Sequence
MTTTAPAPQVYGGDEVATLVIDTGSSYTRVGYAGEDTPKLVVSTECGLMADEDVEMEDDTSNTTKKLNKYKVGDSANLPLPNMEVLHPLTDGIVADWDAVQNIWEYSLARLNADTKTHPLMLTEPCWNTQANKLKALEIAFESLEVPASYLVKDAVASAFAAGKGNALVLDVGSEVASVTPVIDGLVLYKPARRSQYAGDYLDRQIKKVLVSRGIDLTPRFEIKNKKAVEMGEPPVFTKRELPNVTHSFTDLQVSRILSEFKDSMCQVNDVPLTPEISGEAADRVFEFPTGYSTTFGADRLSTSESLFKPSEYPFDGETVPDTARGLSEMVVDTINASNVDVRAHLANNIVITGGGSLVQGLSDRVSKDVTQALSGLKVRVAAASNQEERRHGAWIGGSVLGSLGSFHQLWVSKQEWQEKGGDYLVEKKRFK

Gene
arp4
Protein
IgA receptor
Organism
Streptococcus pyogenes
Length
386 amino acids
Function
Binds IgA of both subclasses, and also binds polyclonal IgG weakly.
Similarity
Belongs to the M protein family.
Mass
43.837 kDa
Sequence
MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAAEIKKPQADSAWNWPKEYNALLKENEELKVEREKYLSYADDKEKDPQYRALMGENQDLRKREGQYQDKIEELEKERKEKQERQEQLERQYQIEADKHYQEQQKKHQQEQQQLEAEKQKLAKDKQISDASRQGLSRDLEASRAAKKELEAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADLAALTAEHQKLKEDKQISDASRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGMLALKRKEEN