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ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)
Length
1589 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
175.153 kDa
Sequence
MVKFEKVPILGKESIHVGYDIHTDMVQTIINDCRSSTYVVVNDTNLSKVPYCQDFVQELRSSLPEGSRLLQYAVKPGEANKTRSTKADIEDYLLSKGCTRDTVIIAIGGGIIGDMVGFVAATFMRGVRVVQVPTSLLAMVDSSIGGKTAVDTPLGKNFIGAFWQPQFVLVDVKWLETLPRREFINGMAEVIKTACIWNGLEFERLESNAELFLRVVNGSKVIKVNGLSTGEVNDIHYTNIEAMLEHTFKLVLESIKVKAEVVSSDERESSLRNLLNFGHSVGHAYEAILTPQALHGECVSIGMIKEAELSRYLGILSPTQVSRLTKILAAYGLPISPEEKWFKDLTLQKKTPLDVLLQKMSIDKKNDGSKKKVVILESIGKCYGKSAHYVNDEDLKFVLTDETLVYPFSNIPQEQAKTIVPPGSKSISNRALILAALGKGTCKIKNLLHSDDTKHMLTAVQELKGASITWEDNGETVVLEGHGGETLTASADPLYLGNAGTASRFLTTLAALVNSSSKQDYVVLTGNARMQQRPIGPLVDSLRTNGTKIDYLKSEGSLPLKIYTSTPFKGGRIELAATVSSQYVSSVLMCAPYAENPVTLALVGGKPISQLYVDMTIKMMEKFGIKVEVSTTEPYTYHIPKGQYTNPPEYIIESDASSATYPLAFAAMTGTTVTVPNIGYESLQGDARFAIEVLRPMGCKVEQTANSTTVTGPPTGSLRPLKHVDMEPMTDAFLTASVVAAVAHDNDTDSANVTTIEGIANQRVKECNRIEAMSTELAKFGVATKELPDGIQIHGINSLDLLQLPSNSTGPIGIESYDDHRVAMSLSLLAGMVNYSKSHPAADIKPVRILERRCTGKTWPGWWDVLHTELGAHLDGAEPLGYLSGKKTKRSVVLIGMRAAGKSTLGRWCSQILGYELCDLDVLFEKQYAKGTVKDFVAEHGWDKFREAEANLFKETVEQYGDGGYVFSAGGGLVENEVSREHLKKYASDGGVVLHLHRDIEETIVFLQSDPTRPAYMEEIRDVWERREKWYNECSNFAFLAPHCSNEKEFQHLRKSFANYITAITGNREVQVPNKRSAFVCLTFGDLTEKASVLPSIVRGCDAVELRVDHLAKYDSQFVSKQLSTLRTATNDLPIVFTLRTKKQGGKFPDEDYTGMARLFDVALKACVEYIDLELTLPIDVQYKVSNTKGYTKIIGSHHDFGAKYPWKDPEWENRYNQALSLDVDVIKFVGTATKFEDNLALERFREEHKSKPLIAINMGEIGKISRVLNPILTPITSEHLPNSSAPGQLTLAQINKIFASMGGITSKKFFVVGNPVSHSRSPVLHNTGYKLNGLPHHFDRFETDSAQVVKETLLDGEPSLGGLAVTIPLKLDIMKYMNQLTDAARVIGAMNTVIPLGNHHFKGDNTDWIGIKHSLTSNGVPEKVSNVAGLVIGAGGTSRAAIYSLHNLGCHRIFVINRTVSKSIELRDSFPQEYNVVAAETTQQIDHLNEHIGIAVSCVPADKDLDTELLAKLERFLHKGKHNSFVPTLLEAAYKPDVTPVMKLAHDKYQWQVVPGRELLVHQGVAQFEIWTGAKAPFQEIFNAVTRD
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Saccharomyces cerevisiae (strain JAY291)
Length
1588 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
174.834 kDa
Sequence
MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDTNLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDTVMIAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNGAKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLPVSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALIIAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTSLAALVNSTPSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDSVFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFGINVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVAAISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGYKLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREEWYKECSNFSFFAPHCSAEAEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTEQTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTKKQGGNFPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSRSPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMDELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGVAVSCVPADKPLDDELLSKLERFLVKGAHAAFAPTLLEAAYKPSVTPVMTISQDKYQWHVVPGSQMLVHQGVAQFEKWTGFKAPFKAIFDAVTKE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
1588 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
174.807 kDa
Sequence
MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDTNLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDTVMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNGAKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLPVSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTSLAALVNSTPSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDSVFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFGINVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVAAISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVATPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGYKLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWYKECSNFSFFAPHCSAETEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTEQTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTKKQGGNFPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSRSPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMDELTDAAKIIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGVAVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWHVVPGSQMLVHQGVAQFEKWTGFKAPFKAIFDAVTKE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)
Length
1588 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
174.739 kDa
Sequence
MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDTNLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDTVMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNGAKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLPVSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTSLAALVNSTPSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDSVFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFGINVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVAAISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGYKLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWYKECSNFSFFAPHCSAEAEFQALRRSFSKHIATITGVREIEIPSGRSAFVCLTFDDLTEQTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGNFPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSRSPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMDELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGVAVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWHVVPGSQMLVHQGVAQFEKWTGFKGPFKAIFDAVTKE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1588 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
174.755 kDa
Sequence
MVQLAKVPILGNDIIHVGYNIHDHLVETIIKHCPSSTYVICNDTNLSKVPYYQQLVLEFKASLPEGSRLLTYVVKPGETSKSRETKAQLEDYLLVEGCTRDTVMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNADEFTRLESNASLFLNVVNGAKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPTQVARLSKILVAYGLPVSPDEKWFKELTLHKKTPLDILLKKMSIDKKNEGSKKKVVILESIGKCYGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQKVVIPPGSKSISNRALILAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGSTLSACADPLYLGNAGTASRFLTSLAALVNSTSSQKYIVLTGNARMQQRPIAPLVDSLRANGTKIEYLNNEGSLPIKVYTDSVFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYVDMTIKMMEKFGINVETSTTEPYTYYIPKGHYINPSEYVIESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSGPPVGTLKPLKHVDMEPMTDAFLTACVVAAISHDSDPNSANTTTIEGIANQRVKECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAMSFSLLAGMVNSQNERDEVANPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTSKKNSKKSVVIIGMRAAGKTTISKWCASALGYKLVDLDELFEQQHNNQSVKQFVVENGWEKFREEETRIFKEVIQNYGDDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQSDPSRPAYVEEIREVWNRREGWYKECSNFSFFAPHCSAEAEFQALRRSFSKYIATITGVREIEIPSGRSAFVCLTFDDLTEQTENLTPICYGCEAVEVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGNFPDEEFKTLRELYDIALKNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVTSDLLPNSAAPGQLTVAQINKMYTSMGGIEPKELFVVGKPIGHSRSPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFGGAAVTIPLKLDIMQYMDELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTAGLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEIKEHVGVAVSCVPADKPLDDELLSKLERFLVKGAHAAFVPTLLEAAYKPSVTPVMTISQDKYQWHVVPGSQMLVHQGVAQFEKWTGFKGPFKAIFDAVTKE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
1579 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
174.232 kDa
Sequence
MLVKVPILGRETIHVGYGVRSHIVETIVGLKSSTYVVINDSNVGRVPYFQELLSDFEAQLPAGSRLLRYVVKPGEANKTRATKEQIEDYLLSEGCTRDTVIVAVGGGIIGDMIGYVAATFMRGVRVVQVPTSLLAMVDSSIGGKTAVDTPLGKNFIGAFWQPEFVLVDIKWLQSLPKREFINGMAEVIKTACIWNADEFQRLETHADEFLHVVNTPKISEKEGFQLYDTDIESIKEHIFKLVLESIKVKAEVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYLGILSATQVARLSKILVAYGLPVSKDEKWFRELTLNKKTPLDTLLKKMSIDKKNDGSKKKVVLLETIGKCYGKSAHVVSDEDLRFVLTDETLVYPFNNIPRDQNKTVTPPGSKSISNRALVLAALGKGTCRIKNLLHSDDTKHMLTAVQELKGANISWEDNGETVVLEGQGGSTLVACENDLYLGNAGTASRFLTSVAALVNSTSQKDHVILTGNARMQQRPIGPLVDSLRNNGIKIDYVKNEGCLPLKVHTDSVFKGGRIELAATVSSQYVSSILMCAPYAENPVTLALVGGKPISILYVEMTIKMMEKFGIKVEKSTTEEYTYIIPKGHYVNPAEYVIESDASSATYPLAFAALTGTTVTVPNIGSASLQGDARFATDVLQPMGCSVTQTATSTTVTGPPVGHLKPLKHVDMEPMTDAFLTACVVAAVAHDNDPTSKNTTTIEGIANQRVKECNRIEAMCTQLAKFGVRTNELPDGIQVHGLHSINDLKVPSIGNEAVGVCTYDDHRVAMSFSLLAGMVNSEQPNSSNPTPVRILERHCTGKTWPGWWDVLHTELGAQLDGAEPLELNSMKNAKKSVVIIGMRAAGKTTISRWCAAALGYKLVDLDTLFEERYGHGMIKDFVSQHGWEKFREEEARIFKEVIENYGDAGYVFSSGGGLVESSESRRILKSFSKSGGYVLHLHRDIEETIMFLQKDPTRPAYVEEIREVWNRRESWYKDCSNFSFFAPHCNSEVEFQNLRRAFTKFIRTITGVTTVDIPTRRSAFVCLTFENLTEYTNSLKAITYGCDAVEVRVDHLSNMDEDFVSKQISILRASTDGLPIIFTVRTKKQGGKFPDEDYETLQKLLITALKVGVDYIDLELTLPIGIQYKVLNMKRNTKIIGSHHDFASAYPWDHSEWENRYNQALAMDVDIVKFVGMAKSFEDNLMLERFRDSHTTKPLIAINMGAHGRVSRVLNTILTPVTSEHLSEVAAPGQLTVAEINRIYTEMGGITKKDFFVVGSPIGHSRSPVLHNTGYSVLGLPHHFDKFETTSAEEVKKHLLDNKANLGGLAVTIPLKLDIIKYMDELTESAKVIGAVNTVIPLGNSKFKGDNTDWLGIRNSLVSNGVPESVSGLSGLVVGAGGTSRAAIFALHKLGCQKIFIVNRTTEKLEELVKFFPEEYNIVPIKEAEEAEAVNETIGVAVNCVPADKPLDAKLESLLERLLLKSSHTHFVSTLVEAAYKPSVTPVMKLAKDKYQWRVVPGAQMLVHQGVAQFETWNNCRAPFKAIYDAVTEI
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
Length
1579 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
172.764 kDa
Sequence
MKVELSKVPILGKDVVHVGFDIADHIVDTIFQSCPSSTYVVINDTNVEKIPHYVDLCGELQAKLKSGSRILQYSVKPGEAHKTREQKAAIEDYLLSEGCTRDTVIIAVGGGVIGDMIGYVASTFMRGVRVVQVPTSLLAMVDSSIGGKTAVDTPLGKNFIGAFWQPQFVFVDIKWLETLPKREFINGIAEVIKTACIWNAEEFARLEENADLFLQVVNGSKTTQVSVQGQVHELSLTNIDAMLEHVYRLVLESIKVKTHVVSSDEREAGLRNLLNFGHTIGHAYEAILTPQALHGECVSIGMIKEAELSRYLNILSPTQVARLTKILAAYGLPISPDQKWFKDLTLNKKTPLDVLLKKMSIDKKNDGSKKKAVLLETIGKCYGTSAHVVSDEDIRFVLTDETLVYPFKTLENGQEKTIVPPGSKSISNRALILAALGEGTCKIKNLLHSDDTKHMLHAVQQLKGATITWEDNGETVVLKGHGGSTLQATAEPLYLGNAGTASRFLTSVAALVNSTSSQKSVVLTGNARMQERPIGPLVDSLRENGISIDYLNKEKSLPLKINTDSNFKGGRIELAATVSSQYVSSILMCAPYAEEPVTLALVGGKPISKLYIDMTIKMMEKFGIYVKASTEEPNTYHIPKGHYVNPPEYVIESDASSATYPLAYAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCSVTQTETSTTVTGPPVGGLKPLKHVDMEPMTDAFLTACVVAAVAHDGKEGSRNTTTIEGIANQRVKECNRILAMVDELAKFGVEANELPDGIQVHGLSSIDKLKVPEAIHSYDDHRVAMSFSLLAGMVGATKDALSEPVRILERSCTGKTWPGWWDVLHTQLGAKLDGSEPLQSAVKKNSNSSIVIIGMRAAGKTTVSSWCANALGFKFLDLDTVFEEQYKKGSVKEFVAEHGWDAFRATETKIFEESVKKYGEGYVLSTGGGIVEGAASRKSLKQFASQGGIVLHLHRDIDETIKFLNSDPTRPAYNEDIRNVWERREEWYKECANFTFYAPHCTSSTQFNQLRKTFETFIRTISGKREVKIPTNRSSFVCLTFDDLAAHKEKIPDITAGCSAVELRVDQLKSYDLDFVAKQLSILRLASSSLPIIFTIRTKSQGGQFPDDDKSTLGSLLSLALEVGVEFVDMELTLSSELQYSLVNNKRNTKIIGSHHDFDAKFDWNDSEWENRYNQALSLDVDVVKFVGTAKDFEDNLKLEQFRLQHTAKPLIAINMTDVGKMSRVLNTVLTPVTSSLLPSASAPGQLTLSQINEIYTLLGGFSAKNFYVVGSPISHSRSPVLHNTGYKILGLPHKFEKFETSSASEVKDKLLSKCKLGGLAVTIPLKLDIMEFMDELSESAKLIGAVNTVIPLGDGKFKGDNTDWLGIYNSFLANGVPENVRGNSGFVIGAGGTSRAAVYALHQLGCSDIHLVNRTVEKPHDLKKSFPSEYNLHVLEDSQQAEGISGSVALAVSCVPADKPLDDNLLARVRAVLAKAQGTSFKPTLLEAAYKPAVTPMMKTASDEFSWHIIPGSQMLVHQGVAQFQLWTGFRAPFNAIYSAVTEEQA
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
1578 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
173.789 kDa
Sequence
MSVELAKVSILGKECVHVGYQIHEHIVKSTLEHCKSSTYVIINDTNVSKVPYYHDLVSLFEKSLPEGSRLLRYDVKPGEAHKSRETKADIEDYLLLEGCTRDTVIIAVGGGVIGDMIGFVASTFMRGVRVIQVPTSLLAMVDSSIGGKTAVDTPLGKNFVGAFWQPQFVFVDIKWLETLPQREFINGIAEVIKTACIWNGEEFARLEANAETFLSVVNNSQTVSVFSPHHNETVELTYTNIESMLEHTYKLVLESIKVKAHVVSSDERESGLRNLLNFGHTIGHAYEAILTPQALHGECVSIGMVKEAELSRYMNILSATQVARMVKILAAYGLPISVNEKWFKELTLNKKTPLDVLLKKMSIDKKNDGSKKKVVILEKIGKCYGTSAHVVSDEDLRFVLSDETLVHPFNNIPEGQNKVITPPGSKSISNRALILAALGKGTCKIKNLLHSDDTKHMLNAVQQLKGATISWEDDGETVVVHGQGGSTLTAPSEALYLGNAGTASRFLTTVAALAKKDGKNDHVILTGNARMQERPIGPLVDSLRSNGLKIDYLNRQGSLPLKINTETNFKGGKIELAATVSSQYVSSILMCAPYAEEPVTLSLIGGKPISQLYVDMTIKMMDAFGIKVTTSTTEPFTYHIPKGNYINPAEYTIESDASSATYPLSFAAITGTTVTVPNIGSASLQGDARFAVDVLRPMGCEVTQTATSTTVTGPPRGQLKPLKHVDMEPMTDAFLTASVVAAICNNGTTNTTTIEGIANQRVKECNRIEAMVTQLAKFGVRANELPDGIQIHGVNSISELRQPSDAGIETYDDHRVAMSFSLLAGMVNSDKKDDESSVRILERQCTGKTWPGWWDVLHSQLGARLDGAEPSTTKSSEVKKSVVIIGMRAAGKSTVSKWCAESLGYRLLDLDEEFERQYGKGTVKDFVAESGWDEFRKEETRIFQEAVDKYGDKGYVLSSGGGIVERSESRQALKRFAESGGIVLHLHRDIEETIVFLKSDPTRPAYIEEIRDVWERREKWYHECSNFTFFAAHCSNEIEFRNLRHVFSNFIRRVLGAEKIPVPSRRSAFVCLTFEDLSDHLSKLDEITYGCEAVELRVDHLSSFSSDFVTKQISLLRAATKSLPIVFTVRTVSQGGKFQDDDYDLLESLLKVALKNAVEYIDLELTLPNNILYNVLNKKSNTKIIGSHHDFAAKFPWDDAEWENRYNQALSLDVDIVKFVGTAVSFDDNLALEKFRSTHTLKPLIAINMTETGKLSRVLNNILTPVTSKLLPSAAAPGQLTLAEINQLYHQIGGLPAKKFFVIGSPIGHSRSPILHNTGYELLGLPHHFDKFETEDIEVVKKELLTREDLGGLAVTIPLKLDIIDSMFELSEAAKTIGAVNTVIPLGKNKFRGDNTDWLGIKNSLVSNGVPSSVSGSAGLIIGAGGTSRAAIYALKQIGCDTIYMLNRTTEKLQKLKSEFSEEYKIVVVESAEQTESIKEQVSVAVSCVPADKPLDPELLNKLERLLAKGTNSSFKPTLLDAAYKPSVTPIMKLARDKFNWNIVPGAEMLVHQGVEQFSKWTGAKPPFKAIFDAVTQE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
1577 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
173.764 kDa
Sequence
MASVGLEKVNILGRDSIHVGYDLRAHIARTVFESCVSSTYVVVSDANVARVPYHEALCAALEEGLPARSRMLRYVVQPGETYKTRETKGEIEDFMLAEGCTRDTVVLAVGGGVIGDMVGFVAATFMRGVRFVQVPTSLLAMVDSSIGGKTAVDTPAGKNFIGSFWQPEFVFVDVKWLETLPRREFINGMAEVIKTACIWNAAEFMRLEMHASMFLQVVNSSKQVKVDTKGGPTSLSYTNITQILDHVFQLVLESIKVKAHVVSSDERESGLRNLLNFGHSIGHAYEALLTPQALHGECVSIGMVKEAELSRYLNILSPTQVARLTKVLSAYGLPTSVNEGWFRELTLGKRTPLEVLLRKMSIDKKNDGSNKKVVLLETIGKCYGTSAHVVSDTDLRFVLTDEALVYPFTDVRSSTGHTIVPPGSKSISNRALILAALGKGKCRIRNLLHSDDTKHMLEAVQQLNAATISWEDNGDTVVIDGHGGRTLTASDLPLYLGNAGTASRFLASVASLVCPEGNRDSVILTGNARMQERPIGPLVESLRLNGVRVDYLNREGSLPIKVHAESKFRGGRINLEASISSQYVSSILMCAPYAEEPVTLSLDGKPISELYIEMTIRMMEKFGIKVEKSNDELYTYHIPRGQYVNPAEYVIESDASSATYPLAFAALTGTTVTIPNIGHDSLQGDSRFACDVLKPMGCTVQQTATSTTVTGPEPGTLKPLEHVDMEPMTDAFLTACVVAAAAHSPESKCKNIITITGIANQRVKECNRILAMVTQLSKFGVTAEELPDGIQVHGVEQLSQLKVPDAVETYDDHRVAMSFSLLAGMVNYGQAPSSCRPIKILERRCTGKTWPGWWDVLHSRLGATLDGNEPLPEKENDIRKSVVLIGMRAAGKSTVGRWCAEALGYKLLDLDDEFQTYFGMGTVKEFVAQNGWESFRSKETDLFGHVLNKYSRSGYVISTGGGIVETASSRKLLQDFAATGGVVLHLYRDIDETIKFLRTDPTRPAYIEEVRGVWDRREKWYHLCSSYSFFSPHCSTTAEFEGLRRVFSKFIRRITGMLPVEVPVKRSTFVCLTFQNLLPEMERIKEAVYGCEAVEVRVDHLENYSQDFVLKQLTALRLATDSLPIVFTIRTKKQGGKFLDNDYSTLEDLLTVGLKAGVEFLDLELTLPSPIHQRILNKRYKTRIIGSHHDFSGEFSWEHPEWEHRYAQALAMQVDAIKFVATAKGFGDNLSLEEFRSKHTDKPLIAINMRECGKLSRVLNTILTPITSDVLPQAAAPGQLTLRQINELYASIGGLRPKKMFVVGSPIGHSRSPILHNTGYNSLGLPYTFDKFETDSAEIVKKSLLSREDLGGIAVTIPLKQDIMQYLDELTDSAKCIGAVNTIIPKKDGRFIGHNTDWLGIKNSLIANGVPEHVNTAGLIVGSGGTARAAAYAFHEMQCSTIYMINRTTSNLTELQKSFPQEFNIHVIESLEQIEQLSEPVGIAVSCVPSDKPLDDALSQKLSAFLSRPSATNFIPTILDAAYKPLVTPVLKLASEVHGWRPVSGAQMLVHQGVAQFEIWTGFKAPFAPVYDAVTQE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Clavispora lusitaniae (strain ATCC 42720)
Length
1568 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
171.942 kDa
Sequence
MSQVEKVSILGSDSIHVGYGIQDHIVEETLTNLKSSTYVIITDSNMEATAPYQTLSSKFEAGLKEFRPESRLFYYAVSPGENNKSRETKAQVEDFLLQKGCTRDTVIIAVGGGVVGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSIGGKTAVDTPLGKNFVGAFHQPKYVFVDVSFLTTLPTRQFINGMAEVVKTAAIWNEEEFTRLENFAKTFIAVVTSDNIDLATIKDDLVKTVLESIRVKADVVSADEKESSLRNLLNFGHTIGHAIEAIVTPQALHGECVAVGMVKEAELARYWGVLSPVAVARLVNCIAAYNLPTSVGDKIFVQRIGHKRHFIQINTLLEKMAIDKKNDGSKIRTVILEAIGKCYQLKAHEVSKQDLSFVLTDETLVHPFQEETTPKENVVIPPGSKSISNRALILAALGKGTVRIKNLLHSDDTKHMLAAVAALKGAEISTEDNGDTIVVKGNGGNFITCDEQLYLGNAGTASRFLTTVASLVNVNEQSNDYTVLTGNARMQERPVGPLVNALRANGSEIEYLNNEGSLPLKIKAGKGLKGGRVELAATISSQYVSSILMCAPYAEKEVTLALVGGKPISQLYIDMTIAMMKDFGISVTRDPHEEHTYHIPKGVYSNPGVYEVESDASSATYPLAFAAMTGTSCTVPNIGSSSLQGDARFAVDVLKPMGCTVEQTSTSTTVRGPSKGSLKPLTHVDMEPMTDAFLTASVVAAIANSSVPTQITGIANQRVKECNRILAMVDELAKFGVRAEELPDGIEIYGIDYKNLKVPSLENRGVCTYDDHRVAMSFSLLAGMCPEPVLITERSCTGKTWPGWWDVLHTKFGVELEGYEEPKDLNDPALLVNKEVNGDKSIVVIGMRAAGKSTLSRWIADFMGFELIDLDTVFEQTHGDIREYIKANGWGRFRELEAGIMKEYLTKCSSRHVISTGGGIVESEESRDILKSYTKTGGIVLHLHRDLDETIVFLSSDTTRPAYVSEIKDVWARREKWYHECSNYHFYSSHCGTEEEFKKLRHSFVSYLKTITGAGLSPVPKGRSFVLSLACSDLNDIAENLEDIVAGCEAIELRVDLLKDYSPSFVADQTAVLRKFVNLPIIYTIRTKGQGGNFPDEDVQALEQLSYLGIKLGVDYLDVQLSNSEKFVKSIIEKKAFTKIIATHIDLAGLPWTRAEWDNKYNQGISLNADVIQLVGFAHAFQDNIDLEQFRANHTITPLIAFNAGEHGKLSRVLNRTLTPVTSELLSNVSGNGQLTVGEINRCFSEIGGLSRRNFYIVGNPISHSRSPQLHTAGYEKLNLPHRFSKFETDYAQKVYEEVMTKPGFGGLAVTIPLKLDIMKYVSELSESAKIIGAVNTVTPLDGQPGKFYGDNTDWYGITQSFVRHGVPSFGNSSVNGMVVGGGGTSRAAAFALHQMGCKKIYMVNRTTSKLHEIKSSLPSDFNIEVLETVDQVEAADPVSLVVSCVPADKPLDSELLNKVERILYHGKNQEKRSFVPTLLDAAYKPRVTPIMKIAEEKFGWAVVPGVEMLVNQGVLQFKVHTVFTPPYKNVYEAVVDDNV
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
1551 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
169.396 kDa
Sequence
MSIEKVPILGKETIHVGYGIADHIVREVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSEKRPESRLLTYCVSPGENNKNRATKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKNDGSKIRCVLLEKIGKCYQLKAHQVSKQDLSFVLTDEVLVHPFTNPPKENIIVPPGSKSISNRALILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGNLVTSGEELYLGNAGTASRFLTTVASLVGKSQASDDVILTGNARMQERPIGPLVDALGSNGSEIEYLNKQGSLPLKISAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEEYTYHIPKGTYKNPSEYVIESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDAKFAVDVLKPMGCKVEQTTTSTTVTGPPRGHLKPLPHVDMEPMTDAFLTASVVAAVAKGGSSTSITGIANQRVKECNRIEAMVTELAKFGVPANELPDGIEIHGIDIEDLKTPEISKRGVSSYDDHRVAMSFSLLAGLCKEPVLILERSTTGKTWPGWWDILHSKFKIELDGYEPPFNTDKHVDKSSDKSIIVIGMRGTGKSTLSEWLASFLGFKMLDMDKYLEEKLGTGIKSLIKAKGWEYFRQEEAIVAKECFTKFSKGYVLSTGGGIVEGEDARQQLKSYADNGGIVLHLHRDLDETVTFLAADTTRPAYSSEVQEVWLRREKWYHECSNYHFYSSHCSTEDEFNHLRRSFVNYIKLITGAERPVVPAGRSAAVVLTSPDLNEVVGDLESITIGADAVELRVDLFKDTSAEFVAAQIAVIRKHADLPIIYTVRTVSQGGKFPDENVDELKSLLLLGIRLGVAYVDLQLTAPNELIEEISSKKGFTRVIGTYQDINGELKWNNVEWKNKYNQGVSMNADIVRLVGKANSIQDNLDLENFKKQNTLKPLIAFNLGSQGKLSQVLNGTFTPISHKLLPNDEEFLTIGELNQTYFDIGGFTAKKFWVIGSPIEHSRSPNLHNAGYKALNLPYQFGRFEATDVDVVYDNLINKPDFGGLAITMPLKLDIMKFATKLSDAAETIGAVNTLIPIEGGYFGDNTDWVGISNSFIRAGVPPKSSSNGLVVGAGGTSRAAIYALHQMGCAKIYLVNRTAAKLEELVKSFPKDYNLEIVETEQQADKASKVSLAVSCIPADKPLDGEVLKKIERILSNGSEQSAGFKPTLLEASYKPRVTPIMKLTEEQYKWKVIPGVEMLVNQGDRQFKLHTGFTAPYEIIHRAVVEE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Candida tropicalis (strain ATCC MYA-3404 / T1)
Length
1551 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
169.663 kDa
Sequence
MSIEKVPILGKETIHVGYGIQDHIVTEVVDNLASSTYVIVTDTNVEKTPQFSKLTNDFTKVLNEKRPDSRVLTYSVPPGENNKNRATKAAVEDFLLQQGCTRDTVIIAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPQYVFIDVSYLESLPTRQFINGMAEVVKTAAIWNEEEFTRLENFSKQFLSVVTAKNPDLLSIKEELVKTVLESVRVKAEVVSSDEKESSLRNLLNFGHTIGHAIEAIVTPEALHGECVSIGMIKEAELARYLGILPPVAVARLSKCLVAYGLPVTIDDKLFLQRVGPKRHNIEIDLLLKKMSIDKKNDGSKIRSVILESIGKCYQLKAHEVSKQDLTFVLTDEVLVHPFKQPPQENVITPPGSKSISNRALILAALGTGTVRIKNLLHSDDTKHMLAAVAALKGAEITTEDNGETIVLKGNGGDLVTCDEELYLGNAGTASRFLTTVASLVGKSESNDHVVLTGNARMQERPIGPLVDALRSNGSEVQYLNKEGSLPLKITAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEDYTYHIPKGTYKNPAEYVIESDASSATYPLAFAAMTGTSCTVPNIGSSSLQGDARFAVDVLKPMGCKVEQTATSTTVTGPPRGQLKPLPHVDMEPMTDAFLTASVVAAVAQGDSSTTITGIANQRVKECNRIEAMITELAKFGVKADELPDGIEIHGIDIADLKTPSIEKRGVCSYDDHRVAMSFSLLSGLCKEPVLILERSTTGKTWPGWWDILHSKFNIELDGYEPPFGTDKEGTKASDKSIIIIGMRGTGKSTLSEWLASFMGFKSLDMDVYLEEKLGNDIKSLIKEKGWEYFREQEAAIAKECFSKFSKGYVLSTGGGIVEGAENRQRLKDYITAGGIVLHLHRDLEETVSFLSVDTTRPAYTSEVKEVWLRREQWYDDCSNYHFYSSHCNTEEEFDHLRKSFVNFIKIITGTEKASIPSGRSAALSLTVPDLNAISSQLGDIAVGAEAVELRVDLLKETSSSFIADQIAVIRKHIDLPIIYTVRTESQGGKFPDNKVEELRNLLLLGVKLGVAFIDVELTAPVEVIEEIIIKKGYTRVIASYNDIAGKLGWSNVEWTNKYNQGVSINADIVKLIGRASSLQDNLELEVFRKQNTLKPLLAVNLGSQGKLSQVLNTIFTPITQESLPNEDGLLTIKEINQIYFDIGGLTAKKFWVIGSPIQHSRSPNLHNAAYKALNLPFTFDRFESTDADQVYKELINKPDFGGLAITMPLKLDIMKYATELSDAAQKIGAVNTLVPLEGGYLGDNTDWVGITSSFTRAGVPPNPRVNGLVIGAGGTSRAAIYALHQIGCEKIYLANRTTSKLNEIKDSFPKEYNLEVLETEDQAEKAQNVGLAVSCVPADKPLDESLLQKVEKILANGEKSSNGFKSTLLEASYKPRVTPMMKIADEKFKWRAIPGVEMLVNQGDRQFQIHTGFTAPYDVIHRAVVEE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)
Length
1550 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
169.361 kDa
Sequence
MSIERVPILGKETIHVGYGIADHIVNEVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSKKRPESRLLTYCVSPGENNKNRVTKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKNDGSKIRCVLLEKIGKCYQLKAHQVSKQDLSFVLTDEVLVHPFTNPPKENIIVPPGSKSISNRALILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGNLVTCGEELYLGNAGTASRFLTTVASLVGKSPASDDVILTGNARMQERPIGPLVDALRSNGSEIEYLNKQGSLPLKISAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEEYTYHIPKGIYKNPTEYVIESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDARFAVDVLKPMGCKVEQTATSTTVTGPPRGHLKPLPHVDMEPMTDAFLTASVVAAVAKGGSTSITGIANQRVKECNRIEAMVTELAKFGVSANELPDGIEIHGIDIKDLKTPEISDRGVCSYDDHRVAMSFSLLAGLCKEPVLILERSTTGKTWPGWWDILHSKFKIELDGYEPPFNTDKHVIKSSDKGVIVIGMRGTGKSTLSEWLASFLGFKMLDMDKYLEEKLGTDIKSLIKAKGWEHFRKEEAIVAKECFTKFSKGYVLSTGGGIVEGEDARQQLKSYADNGGIVLHLHRDLDETVTFLAADTTRPAYSSEVQEVWLRREKWYHECSNYHFYSSHCSTEDEFNHLRKSFVNYIKLITGAERSVVPTGRSTAVVLTLPDLNNVAGDLESITIGADAVELRVDLLKDTSAAFVAAQIATTRKHADLPIIYTVRTVSQGGKFPDENVDELKSLLLLGIRLGVAYIDLQLTAPNELIEEISSKKGFTRIIGTYQDINGELKWNNVEWKNKYNQGVSMNADIVRLVGRANSIQDNLDLEDFKKQNTLKPLIAFNLGTQGKLSQVLNGTFTPISHQLLPNDDGLLTIGEINQTYFDIGGFTAKKFWVIGSPIEHSRSPNLHNAGYKALNLPYQFGRFEATDVDVVYDNLINKSDFGGLAITMPLKLDIMKFATKLSDAAETIGAVNTLIPVEGGYFGDNTDWVGISNSFIRAGVPPKSSSNGLVVGAGGTSRAAIYALHQMGCTKIYLVNRTVAKLEELVKSFPKDYNLEIVETEQQADKVNKVLLAVSCIPADKPLDSDVLKKIERILSNGSEQVAGFKPTLLEASYKPRVTPIMKLAEEQYKWKVIPGVEMLVNQGDRQFKLHTGFSAPYEIIHRAVVEE
Protein
Pentafunctional AROM polypeptide: ARO1

Gene
ARO1
Protein
Pentafunctional AROM polypeptide
Organism
Komagataella phaffii (strain GS115 / ATCC 20864)
Length
1545 amino acids
Function
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Similarity
In the C-terminal section; belongs to the shikimate dehydrogenase family.
Mass
170.055 kDa
Sequence
MSGLIEKVSILRNDSIHVGYNMSSHIVDEILTKKASSTYVLITDSNIVKMGHLQTFVDEFNRLIPSKRPGSRILTYVVPPGEANKNRATKAAIEDYLLEKGCTRDTFILAIGGGVIGDMIGYVAATFMRGVRFVQIPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPDYVFVDVAFLETLPEREFINGMAEVVKTAAIWNEQEFSRLETYSKRFLKVIRDRRVDDSVDLTSLKEHIIKLVLESIKVKAEVVTLDEREGGLRNLLNFGHSIGHAIEAILTPQALHGECVSIGAVLEAELSRYLGILSPVAVSRLYKCFAAYGLPVSIADKLVQKRTNGKKCPVDVLLQKMAIDKKNDGSKKKVVLLSKIGKCYEPKASYVNDEDLRFVLTDEVLVKDFNSAPSTAVVVPPGSKSISNRALILAALGKGECKIKNLLHSDDTEHMLNAVAALKGADISFDDNGETVVVTGNGGNFTATDAEIYLGNAGTASRFLTSVASIVKPDSNTTHVILTGNARMQERPIGPLVDALRTNGSDIEYLNREGSLPLKIKSGNGLKGGRIELAATISSQYVSSVLMCAPYASEPVTLSLVGGKPISLLYVDMTIAMMKSFGIEVTKSTTEPYTYHVPQGHYVNPAEYVIESDASSATYPLAFAAMNGTQVTIPNIGSSSLQGDARFAVDVLKPMGCKVEQTATSTTVQGPTKGTLKPLPLVDMEPMTDAFLTASVVAAIANDTNQSTSIVGISNQRVKECNRIEAMITQLAKFGVRAKELEDGIEVFGIDYHHLKTPSDGVYTYDDHRVAMSLSLLAGLAESPVLIQERHCTGKTWPGWWDILHTTFNVELDGHEAVVETTTAKANEDKSIIVIGMRAAGKSTLSHVIAQTLKGFKVVDLDDVFVEKYGDIREFIKENSWELFREKEAMIAKEAFKNYSKNTVISTGGGIVETEASRKLLKQQMKDGHIVLHLHRDIEETVVFLSQDKTRPAYVDEINQVWERRKNLYKECSNYFFFSPHCQTEREFFTLKKTFSKFINRITGGAVPSIPNGRSAFVCLTYEDLAPVSSKLTRVTNGCDAVELRVDLLKQHDSHFISNQIGILRNQTSVPILFTIRTKSQGGRFPDDSYEDIERLLNLAIKLGVEYVDLELSLPESLLDSVASKRQFTKIIGSHHDFSGTVKWNNVEWENKYLLALKLNVDIIKFVGTATSLNDNWELEHFRSLHTDKPFIGINMGPLGKVSRVFNTILTPVTHKDLPSSAAPGQLTLKEINEYFGQFGGSSRKKFYIVGKPISHSKSPELHKTFYDEFGLSHTFDKFETDDAAKVFNDLVKGNDELGGCAVTIPLKIDMLKYVNELTDSAKSIGALNTIIPIGDGRFIGDNTDWIGIRDSLHQAGCEIAPESSVGLVVGGGGTSRAAVYALHQMGCSKIYMLNRTPSKLSEIKNHFPSNYNIHIVDSLDAIDEDDKLDAAVSTVPGDKPLDDQLISLLKKLLEKKRGHAVLLEAAYKPRETPIMALAFSRGWKVVPGSKMLVNQGIEQFYKWTGYQFSSHIDL
Protein
Pentafunctional AROM polypeptide: ARO1