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ARL8B

Gene
ARL8B
Protein
ADP-ribosylation factor-like protein 8B
Organism
Bos taurus
Length
186 amino acids
Function
Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.511 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFQSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Gene
ARL8B
Protein
ADP-ribosylation factor-like protein 8B
Organism
Homo sapiens
Length
186 amino acids
Function
Plays a role in lysosome motility (PubMed:16537643, PubMed:25898167). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (PubMed:15331635).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.539 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Gene
ARL8B
Protein
ADP-ribosylation factor-like protein 8B
Organism
Macaca fascicularis
Length
186 amino acids
Function
Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.581 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRYRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQYSKSRRS

Gene
Arl8b
Protein
ADP-ribosylation factor-like protein 8B
Organism
Mus musculus
Length
186 amino acids
Function
Plays a role in lysosome motility (PubMed:30174114). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (PubMed:30174114). May play a role in chromosome segregation (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.539 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Gene
ARL8B
Protein
ADP-ribosylation factor-like protein 8B
Organism
Pongo abelii
Length
186 amino acids
Function
Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.587 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAAYREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Gene
Arl8b
Protein
ADP-ribosylation factor-like protein 8B
Organism
Rattus norvegicus
Length
186 amino acids
Function
Plays a role in lysosome motility (By similarity). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
21.539 kDa
Sequence
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Gene
ARL8B
Protein
ADP-ribosylation factor-like protein 8b
Organism
Arabidopsis thaliana
Length
184 amino acids
Function
(Microbial infection) Component of tomato mosaic virus (ToMV) RNA replication complexes. Required for tobamovirus multiplication, especially for efficient negative-strand RNA synthesis and viral RNA capping.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.404 kDa
Sequence
MGLWDALLNWLRSLFFKQEMELSLIGLQNAGKTSLVNVVATGGYSEDMIPTVGFNMRKVTKGSVTIKLWDLGGQPRFRSMWERYCRSVSAIVYVVDAADPDNLSVSKSELHDLLSKTSLNGIPLLVLGNKIDKPGALSKEALTDEMGLKSLTDREVCCFMISCKNSTNIDQVIDWLVKHSKSSN