AQP7

Aquaporin-7

342 amino acids

Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (By similarity). The channel is also permeable to urea (By similarity). Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity).

Belongs to the MIP/aquaporin (TC 1.A.8) family.

37.196 kDa

MVQTSRHRRSTRGSKMVSWSVMAKIQEILQKKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGHISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYTLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNAALPGTQALVIGILVVIIGVSLGMNTGYAINPSRDLPPRVFTFIAGWGKEVFSEGENWWWVPVVAPLLGACLGGIIYLVFIGSTTPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVRPAPPLHESMALGHF

AQP7

Aquaporin-7

315 amino acids

Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis (PubMed:23761966).

Belongs to the MIP/aquaporin (TC 1.A.8) family.

34.796 kDa

MAHNEKDPSSVEPIKRKRFSNEYVRLFLAEFLGTFILIVFGCGTVAVTILSKHQSQDFFSVNVGFFLGIAFGVFIAGGVSGGHLNPAVTLAFAVINKCKWRKVPVYMAAQYLGAWVGSAILTAIYYDALHNHDQGNRTIETAGIYASYPQEFLTWQGGLADQIFATLLLMMGILALTDERNMVGPTGRAYVPLLVGLLVLAIGLAFGFNCGYPINPARDFGPRLFTAMAGWGTQVFSEPRGTYNWWWIPIIGPHVGAIIGALAYNFFIGYHWPKERDDVQLQSPSSPIVIVKNDAYQPLRPSRSVYSEELRITTS

Aqp7

Aquaporin-7

303 amino acids

Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (PubMed:15591341, PubMed:15746100, PubMed:16009937). The channel is also permeable to urea (By similarity). Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids (PubMed:15591341, PubMed:16009937). Mediates glycerol export from adipocytes (PubMed:15591341, PubMed:15746100, PubMed:16009937). After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia (PubMed:15591341). Required for normal glycerol reabsorption in the kidney (PubMed:15998844, PubMed:17077387).

Belongs to the MIP/aquaporin (TC 1.A.8) family.

32.667 kDa

MAPRSVLETIQSVLQKNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWWWVPVVAPLLGAYLGGIVYLGLIHPSIPQDPQRLENFTARDQKVTASYKNAASANISGSVPLEHF

Aqp7

Aquaporin-7

269 amino acids

Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (PubMed:9252401). The channel is also permeable to urea (PubMed:9252401). Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity).

Belongs to the MIP/aquaporin (TC 1.A.8) family.

28.882 kDa

MAGSVLENIQSVLQKTWVREFLAEFLSTYVLMVFGLGSVAHMVLGERLGSYLGVNLGFGFGVTMGIHVAGGISGAHMNAAVTFTNCALGRMAWKKFPIYVLGQFLGSFLAAATTYLIFYGAINHYAGGELLVTGPKSTANIFATYLPEHMTLWRGFVDEVFVTGMLQLCIFAITDKLNSPALQGTEPLMIGILVCVLGVSLGMNTGYAINPSRDLPPRFFTFIAGWGKKVFSAGNNWWWVPVVAPLLGAYLGGIVYLGLIHAGIPPQGS