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AP3S1

Gene
AP3S1
Protein
AP-3 complex subunit sigma-1
Organism
Bos taurus
Length
193 amino acids
Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
Similarity
Belongs to the adaptor complexes small subunit family.
Mass
21.732 kDa
Sequence
MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Gene
AP3S1
Protein
AP-3 complex subunit sigma-1
Organism
Homo sapiens
Length
193 amino acids
Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Similarity
Belongs to the adaptor complexes small subunit family.
Mass
21.732 kDa
Sequence
MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Gene
Ap3s1
Protein
AP-3 complex subunit sigma-1
Organism
Mus musculus
Length
193 amino acids
Function
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Similarity
Belongs to the adaptor complexes small subunit family.
Mass
21.732 kDa
Sequence
MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK

Gene
ap3s1
Protein
AP-3 complex subunit sigma
Organism
Dictyostelium discoideum
Length
171 amino acids
Function
Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
Similarity
Belongs to the adaptor complexes small subunit family.
Mass
19.94 kDa
Sequence
MIKSILIINNHGKPRLIKFYEHYSEEKQQQIIRELFLLVSKRTERSCNFLEIGNNSNIFDKDTKIIYRHYATLFFIFCVDSSESELSIIDLIQTFVESLDKCFENVCELDLIFHIDKVHYILDEMVMGGLVLETNPTIIFSNYEIQNKLEKAENPLLSGLAGVMQTIKPNK