Function
Binds tightly to placental ribonuclease inhibitor and has very low ribonuclease activity. Has potent angiogenic activity. Angiogenin induces vascularization of normal and malignant tissues. Abolishes protein synthesis by specifically hydrolyzing cellular tRNAs.
Similarity
Belongs to the pancreatic ribonuclease family.
Sequence
QNDAYRGFLRKHYDPSPTGHDDRYCNTMMERRNMTRPCKDTNTFIHGNSDDIRAVCDDRNGEPYRNGLRRSRSPFQVTTCRHRGGSPRPPCRYRAFRANRVIVIRCRDGFPIHLEENFIPPRP