Protein
Low-salt glycan biosynthesis hexosyltransferase Agl5
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Function
Hexosyltransferase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1.75 M instead of 3.4 M). Participates in the formation of the tetrasaccharide present at 'Asn-532' of S-layer glycoprotein Csg, consisting of a sulfated hexose, 2 hexoses and rhamnose. Together with Agl6, mediates the addition of sugars 1 and 2 to dolichol phosphate in the tetrasaccharide.
Similarity
Belongs to the glycosyltransferase group 1 family.
Sequence
MGQDSGGLPHYTAELANSMSEYARVTVLKPNETSADEVLRDEITVINAFKPTDISMQNLFDLKLDVLDSIRGLFSFWNIKLINQIDPDIVHDPTDEFPQVNLFSWVHSVYEDRPYVVTSHETKHGGAGGVLRVVNPLLSLVPDFEKSAAIVHSADQRELLLNNHKAVDEVHVIPHGVYSFFRELDYDEQKEEDKHALFFGSLIPPKGIEYLIDAVPKVSEEVPGFSLTIAGSGSIPDECADVVEQYSDVINIRNEFIPNEEVGTLFSRAQVVVLPYRRGWQTGHSGTLSIAFAFGKPIITSEVGDFPELVGESGAGIVVEPESPEAIADGLIEVFSSDSALDQMSNASSRVADRLSWEKIAEQHFEVYQNLL