Afmid

Kynurenine formamidase

305 amino acids

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.

Belongs to the kynurenine formamidase family.

34.229 kDa

MAFPSLSAGQNPWRNLSSEELEKQYSPSRWVIHTKPEEVVGNFVQIGSQATQKARATRRNQLDVPYGDGEGEKLDIYFPDEDSKAFPLFLFLHGGYWQSGSKDDSAFMVNPLTAQGIVVVIVAYDIAPKGTLDQMVDQVTRSVVFLQRRYPSNEGIYLCGHSAGAHLAAMVLLARWTKHGVTPNLQGFLLVSGIYDLEPLIATSQNDPLRMTLEDAQRNSPQRHLDVVPAQPVAPACPVLVLVGQHDSPEFHRQSKEFYETLLRVGWKASFQQLRGVDHFDIIENLTREDDVLTQIILKTVFQKL

AFMID

Kynurenine formamidase

303 amino acids

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.

Belongs to the kynurenine formamidase family.

33.992 kDa

MMDVSGVGFPSKVPWKKMSAEELENQYCPSRWVVRLGAEEALRTYSQIGIEATTRARATRKSLLHVPYGDGEGEKVDIYFPDESSEALPFFLFFHGGYWQSGSKDESAFMVHPLTAQGVAVVIVAYGIAPKGTLDHMVDQVTRSVAFVQKRYPSNKGIYLCGHSAGAHLAAMMLLADWTKHGVTPNLRGFFLVSGVFDLEPIVYTSQNVALQLTLEDAQRNSPQLKVAQAQPVDPTCRVLVVVGQFDSPEFHRQSWEFYQTLCQGEWKASFEELHDVDHFEIVENLTQKDNVLTQIILKTIFQ

afmid

Kynurenine formamidase

294 amino acids

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.

Belongs to the kynurenine formamidase family.

32.682 kDa

MSRWKDMNKDELERQFSPSQWSHRMSADDVIKSHVTALKEGTERARGLAQTLLNVPYGEGEGEKLDVYVPTTTSLDVPLVIYLHGGYWQFLSKEESGFMAVPLVHKGVVVVAVGYDIAPKGNMDVMVSQVRRSVVSVIQQYSHISGLYLCGHSAGAHLAAMILSTDWSQYSVTPQIKGAFLVSGIYDLLPILSTYVNEPLKMTEEVALRNSPSQLVPQLKLSSSNCDIVVAVAQNDSPEFRKQSEDYYKALESTEGLKVTLEDVPNTDHFNIIEQLVDGDYHLTQLLLKMMGKS

afmid

Kynurenine formamidase

293 amino acids

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.

Belongs to the kynurenine formamidase family.

32.412 kDa

MSDWKSMSKDELELQYSPSRWSPRMSADDVIRAHVSALKSGTERARSVTQTLMDVPYGEAEGEKLDVYLPSSSSPDVPLVIYFHGGYWQFLSKDESGFLAVPLVQKGAVVVAVGYSIAPKGDMDLMVSQVRRSVVSVIQQYSHISGLYLCGHSAGAHLAAMVLSTDWTQYDVSPKIKGAFLVSGIYDLQPILSTYVNEPLKMTEEVALRNSPSRFLSQLKVSSASCDITVAVAQNDSPEFRKQSEEYYKALESAGLKVSFEDVSETDHFSIIEQLVDENYLLTKLLLKMIGKS