Afm

Afamin

608 amino acids

Functions as carrier for hydrophobic molecules in body fluids. Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier.

Belongs to the ALB/AFP/VDB family.

69.379 kDa

MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTTYLAIIAFSQYVQEASFDEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFPRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLHLYMYEVARRNPFVFAPVLLAVAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINVAVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVVNHICSKQDSISSKIKVCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSRRHPDLSTPELLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECKQFQELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLGELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYELPSVSALVSALHTDWCQPRKEDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDESQATEKQR

Afm

Afamin

608 amino acids

Functions as carrier for hydrophobic molecules in body fluids. Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier.

Belongs to the ALB/AFP/VDB family.

69.335 kDa

MRHLKLTGFIFFLLSLTESLALPTKPQDVDHFNATQKFINENVAYLTIIASAQYVQEASFEEVEMLVKVMLDYKDRCLADSTLPECSKIANDAIQDMLCDMKGLPQKHNFSHCCRQAGFQRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLNLYMYEVARRNPFAFAPVLLNVAARFEEAATTCCEQQQKATYFQDKAAPITQYLKALSSYQRNVCGALLKFGPKTLNSINIAVFSKKFPKIGFEDLTSLLEDVSSMYDGCCEGDVVQCIRSQSQVMHHICSKQDSISSKIKACCEKKLPERADCIINANKDDRPEDLSLRTPKFTDSENVCQERDSEQDKFFAEFLYDYSRRHTELSTPELLRITKVYKDLLEDCCNRKNPLSCYRHAEDKFNETTERSLAMVQQECKQFQELGKDALQRHFLVKFTKAAPQLPMEELVSLSKEMVAALATCCTLSDEFACVDNLADLVLGELCGMNKNRTINPTVDHCCRADFAFRRPCFEHLKADTTYALPSVSALVSALRADWCQPLKEDLQNKRHRFLVNLVKWMPEITDEERLCLFTKFTAAGEECGNIQKPEACFSPESSKTGDVSQDAEKQR

AFM

Afamin

604 amino acids

Functions as carrier for hydrophobic molecules in body fluids. Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720). Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier (By similarity).

Belongs to the ALB/AFP/VDB family.

69.562 kDa

MKQLKLTGFVIFFFFLTESLTLPTQPQDVDDVRITQKFIDDNIGYITIIAFAQYIQEASFEEVEMLVKAMTEYRDKCLADRTLPECSKLANEVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFFHNKKADIGLLPPLPTLDPEEKCQTYKNNRESFLNNYVYEVSRRNPFVFAPTLLTVAARFEEMTKTCCEEQEKANCFQTKAEPFIYYLKALSSYQKNACRALMKFGRQILQSINIAILSQKFPKIGFKQLTSLLEDVSSKYDGCCEGDVVQCIRGRSKVMSHICSKQDSISSKIKDCCEKKIPERGECIIYSNKDDRPNDLSLREAKFIESDNVCEKRDADQANFMAEFLYEYSRRHPELSTPELLRIAKVYKDLLKECCNMENPPECYRHAENRFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLINLTKLAPQLSTEELTFLGKEMVMALTTCCTLSEEFACVDNLVDLVLGELCGINENRNINPAVDHCCKTNFAFRRSCFESLEADKTYVPPSTSQGLFTFHADLCQAHNEELQRKKDRFLVNLVKLKPELAGEELWSLLADFTNVVEKCCKAQEPEACFKEESPKLAAKSQAA

AFM

Afamin

599 amino acids

Functions as carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720). Binds vitamin E (PubMed:15952736, PubMed:12463752). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed:15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed:19046407).

Belongs to the ALB/AFP/VDB family.

69.069 kDa

MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN