Protein
Actin-depolymerizing factor 1
Organism
Arabidopsis thaliana
Function
Actin-depolymerizing protein. Stimulates F-actin depolymerization. Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables (PubMed:11402164). Severs actin filaments or bundles and promotes actin cytoskeleton disassembly (PubMed:21570971). Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin (PubMed:17538023).
Similarity
Belongs to the actin-binding proteins ADF family.
Sequence
MANAASGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVVVEKVGQPIQTYEEFAACLPADECRYAIYDFDFVTAENCQKSKIFFIAWCPDIAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVFRSRAN