About Products Protein Database Contact

ABM

Gene
ABM
Protein
Jasmonate monooxygenase ABM
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
215 amino acids
Function
Monooxygenase that converts the endogenous (and likely the host) jasmonate (JA) to its hydroxylated derivative 12-hydroxyjasmonate (12OH-JA), also known as tuberonic acid, a compound that attenuates or disables jasmonate-based host innate immunity and which is essential for proper initiation and elaboration of the blast disease in rice (PubMed:26258762). ABM, together with a polyketide synthase MGG_04775 and the esterase MGG_04774, share the secondary metabolism gene cluster with ABC transporter ABC3, and therefore may also be involved in the synthesis of other important metabolites such as the ABC3 transporter efflux substrate (ATS) and/or additional polyketides (Probable).
Mass
24.042 kDa
Sequence
MFAVIFETRPQPSQFDTYLTIAKSLRPELANIDGFIENIRYKSLSRPGWILSLSFWRDEKSLVRWRTTATHHMAQEKGRDGVLEDYHLRVGQVTASVRSNEVKRVETVDAREQDDVTAVGAAKTVQLVRFQMDRGAGIDAAAGKLGLNPEEPRGLLAWDIMEAVLSPGDMILLASWETGSSSVSIPGADSDEVQVLRDYGKYDRREAPQFYPPAS