Protein
Transcript termination protein A18
Organism
Cowpox virus (strain GRI-90 / Grishak)
Function
DNA helicase which seems to act as a postreplicative transcription termination factor. Involved in ATP-dependent release of nascent RNA. Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).
Similarity
Belongs to the helicase family. Poxviruses subfamily.
Sequence
MSLLKMEYNLYAELKKMTCGQTISLFNEDGDFVEVEPGSSFKFLIPKGFYSSPSVKTSLVFETLTTTDNKITSINPTNAPKLYPLQRKVVSEVVSNMRKMIELKRPLYITLHLACGFGKTITTCYLMATHGRKTVICVPNKMLIHQWKTQVEAVGLEHKISIDGVSSLLKELKTQSPDVLIVVSRHLTNDAFCKYINKHYDLFILDESHTYNLMNNTAVTRFLAYYPPMMCYFLTATPRPANRIYCNSIINIAKLSDLKKTIYVVDSFFEPYSTDNIRHMIKRLDGPSNKYHIYTEKLLSVDEPRNQLILNTLVEEFKSGTINRILVITKLREHMVLFYKRLLDLFGPEVVFIGDAQNRRTPDMVKSIKELNRFIFVSTLFYSGTGLDIPSLDSLFICSAVINNMQIEQLLGRVCRETELLDRTVYVFPNTSIKEIKYMIGNFVQRIISLSVDKLGFKQESYRKHQESDPTSACTASSREERVLNRIFNSQNR