Protein
Phage tubulin-like protein
Organism
Pseudomonas phage 201phi2-1
Function
Tubulin-like protein that forms filaments during the lytic phase, which are required for positioning the phage DNA at the center of the bacterial host cell for optimal viral replication (PubMed:22726436). The filaments have a three-stranded achitecture and form a spindle-like cytoskeleton within the infected cell (PubMed:24631461). Displays GTPase activity (PubMed:22726436).
Sequence
MPVKVCLIFAGGTGMNVATKLVDLGEAVHCFDTCDKNVVDVHRSVNVTLTKGTRGAGGNRKVILPLVRPQIPALMDTIPEADFYIVCYSLGGGSGSVLGPLITGQLADRKASFVSFVVGAMESTDNLGNDIDTMKTLEAIAVNKHLPIVVNYVPNTQGRSYESINDEIAEKIRKVVLLVNQNHGRLDVHDVANWVRFTDKHNYLIPQVCELHIETTRKDAENVPEAISQLSLYLDPSKEVAFGTPIYRKVGIMKVDDLDVTDDQIHFVINSVGVVEIMKTITDSKLEMTRQQSKFTQRNPIIDADDNVDEDGMVV